Nationwide Children's Hospital

239 total trials 196 currently recruiting 32 completed

Trial Pipeline

RECRUITING Early Phase 1

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

NCT06333899

RECRUITING Phase 2

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

NCT06838676

RECRUITING

Observation Study in Patients Age 0-5 Years With LAMA2-related Congenital Muscular Dystrophy

NCT06503367

RECRUITING Phase 1

Phase 1 Study of Locoregional Injections of Ex Vivo Expanded Natural Killer Cells

NCT04254419

RECRUITING NA

Pediatric Cochlear Implant Remote Programming and Assessment

NCT07035873

RECRUITING NA

Preparing for Life and Academics for Young Childhood Cancer Survivors

NCT06769334

RECRUITING Phase 2

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

NCT05843253

RECRUITING

Targeted Pediatric High-Grade Glioma Therapy

NCT05839379

RECRUITING Phase 2

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

NCT05096481

RECRUITING NA

Applying Directly Observed Therapy to Hydroxyurea to Realize Effectiveness

NCT06264700

RECRUITING NA

GERD Infant Feeding Therapeutics Trial (GIFT Trial)

NCT06114836

RECRUITING NA

Improving Status Epilepticus Treatment Times

NCT06194747

RECRUITING NA

αβT Cell/CD19+ B Cell Depletion for Alternative Donor Allogeneic Hematopoietic Cell Transplantation (HSCT)

NCT06082947

RECRUITING

DOSC and Association With Neighborhood Opportunity: Phase II

NCT05939570

RECRUITING Phase 2

MEKTOVI® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma

NCT05286788

RECRUITING NA

Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants

NCT05547165

RECRUITING Phase 2

ACTEMRA® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma

NCT05233397

RECRUITING Phase 1

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

NCT05278208

RECRUITING Phase 1

A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue

NCT05634369

RECRUITING Phase 1

NK Cells Infusions With Irinotecan, Temozolomide, and Dinutuximab

NCT04211675

RECRUITING Phase 2

A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors

NCT05135975

RECRUITING Phase 2

Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

NCT05267821

RECRUITING Phase 1

Safety and Efficacy of Expanded, Universal Donor Natural Killer Cells for Relapsed/Refractory AML

NCT05503134

RECRUITING Phase 1

Pilot Study of Haploidentical Donor Adenovirus Specific T-lymphocytes to Treat Refractory Adenovirus Infections

NCT04722029

RECRUITING Early Phase 1

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

NCT04655404

RECRUITING Phase 2

Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts

NCT04467671

RECRUITING

Early Predictors of Necrotizing Enterocolitis in Neonates

NCT03210831

RECRUITING NA

Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease

NCT03622359

RECRUITING

Genetics of Congenital Heart Disease

NCT01192048

ACTIVE NOT RECRUITING

Metabolomic Profiling of Racial Disparity

NCT06266429

ACTIVE NOT RECRUITING NA

Regional Anesthesia EMG Study

NCT06287151

ACTIVE NOT RECRUITING NA

VR-PAT for Pain and Anxiety Management During Pediatric Dermatologic Laser Procedures

NCT05645224

ACTIVE NOT RECRUITING NA

Evaluating an Intervention to Prevent Overdoses in Rural and Urban Counties

NCT05463341

ACTIVE NOT RECRUITING

Natural History Study of Patients With VCP-related Disease

NCT04823143

ACTIVE NOT RECRUITING

Early Prediction of Spontaneous Patent Ductus Arteriosus (PDA) Closure and PDA-Associated Outcomes

NCT03782610

ACTIVE NOT RECRUITING Phase 4

GM-CSF for Reversal of immunopAralysis in pediatriC sEpsis-induced MODS Study

NCT03769844

ACTIVE NOT RECRUITING Phase 1

A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma

NCT03605550

ACTIVE NOT RECRUITING Phase 1

Haploidentical Hematopoietic Cell Transplantation for Children With Hematologic Malignancies and Myelodysplasia

NCT03431090

ACTIVE NOT RECRUITING

Characterization of Clinical Skeletal and Cardiac Impairment in Carriers of DMD and BMD

NCT02972580

ACTIVE NOT RECRUITING Phase 2

MIBG Therapy for Patients With MIBG Avid Tumors

NCT02378428

COMPLETED

Preoperative Survey to Evaluate Patient Allergy

NCT05670756

COMPLETED Phase 3

Baclofen for Children With Rumination Syndrome

NCT05975684

COMPLETED NA

An Immediate Functional Progression Program for Adolescent Athletes With Spondylolysis

NCT05505981

COMPLETED

Parental Perceptions on Prescription Opioid Use

NCT05344118

COMPLETED NA

Decreasing Antibiotic Duration for Skin and Soft Tissue Infection Using Behavioral Economics in Primary Care

NCT05226260

COMPLETED Phase 2

VR for Burn Dressing Changes at Home

NCT04548635

COMPLETED NA

VR for Pain Management During Adult Burn Dressing Change

NCT04545229

COMPLETED

Comparison of Blood Pressure Measurements in Upper and Lower Extremities in Children Under General Anesthesia

NCT03220906

COMPLETED Phase 3

Impact of Intraoperative Fluid Management on Electrolyte and Acid-base Variables

NCT03054922

COMPLETED NA

Feasibility of Using Functional Progression to Guide the Treatment of Adolescent Low Back Pain

NCT02861456

COMPLETED NA

Evaluation of a Treatment Algorithm for Patients With Patellofemoral Pain Syndrome

NCT02461095

COMPLETED

Rest Before Physical Therapy in Adolescents With Active Spondylolysis and Spondylolisthesis

NCT02332200

COMPLETED NA

Qualitative Sweat Distribution During Tilt Table Procedure

NCT02329548

COMPLETED

Virtual Temporal Bone Surgery: Defining and Translating Metrics

NCT01493765

COMPLETED

Neuronal Ceroid Lipofuscinosis and Associated Sleep Abnormalities

NCT01966757

COMPLETED Phase 4

Tranexamic Acid in Adolescents With Heavy Menstrual Bleeding

NCT01846507

COMPLETED NA

Pilot Trial of Phototherapy for Acute Depression in Hospitalized Cystic Fibrosis Patients

NCT01822197

COMPLETED NA

Abdominal and Lower Extremity Compression During Tilt Table Testing in Adolescent POTS Patients

NCT01795469

COMPLETED NA

Effect of Vitamin D on the Honeymoon Period in Children and Adolescents With Type 1 Diabetes

NCT01724190

COMPLETED

Changes in Tissue Oxygenation Following Regional Anesthesia

NCT01418690

COMPLETED NA

Sedation During Muscle Biopsy in Patients With Duchenne Muscular Dystrophy

NCT01645098

COMPLETED

Accuracy of Using the CPAP Technique to Eliminate Air Leak and Prevent Excessive Endotracheal Tube Cuff Pressures

NCT01384318

COMPLETED NA

Use of a Multimedia Presentation for Informed Consent

NCT01955070

COMPLETED

CNAP™ Monitor Study

NCT01356082

COMPLETED

Retrospective Femoral Nerve Block Study

NCT01293136

COMPLETED NA

Impact of Using a Cuffed Endotracheal Tube on Limiting the Risk of Airway Fire

NCT01285804

COMPLETED Phase 2

Dexmedetomidine Versus Fentanyl Following Pressure Equalization Tube Placement

NCT01188551

COMPLETED

Masimo CO-Oximeter Study

NCT01184521

COMPLETED Phase 1

Repeated Infusions of Mesenchymal Stromal Cells in Children With Osteogenesis Imperfecta

NCT01061099

COMPLETED Phase 1

Reducing Antipsychotic-Induced Weight Gain in Children With Metformin

NCT01231074

COMPLETED

Use of an Ambulatory Capsule to Characterize Gastrointestinal Pressure Patterns in Children

NCT01026922

COMPLETED Phase 2

Measures to Lower the Stress Response in Pediatric Cardiac Surgery

NCT00848393

Phase Distribution

PhaseTrial count
Phase 1 70
Phase 2 66
Phase 3 2
Phase 4 2

What the Pipeline for Nationwide Children's Hospital Shows

According to the ClinicalTrials.gov registry, Nationwide Children's Hospital is linked to 239 US clinical trials across every stage of research activity. Of those, 196 studies are currently recruiting — about 82% of the sponsor's indexed portfolio — and 32 are already marked complete, representing roughly 13% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for Nationwide Children's Hospital reports 4 late-stage studies (Phase 3 and Phase 4 combined) and 136 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for Nationwide Children's Hospital is High Grade Glioma with 8 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial