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NCT06423768 · ClinicalTrials.gov registry record
fMRI in CardiaC arrEst With Uncertain Prognosis
A clinical trial of Cardiac Arrest, sponsored by Brigham and Women's Hospital.
- Active
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT06423768: Active study of Cardiac Arrest, sponsored by Brigham and Women's Hospital.
NCT06423768 is a study of Cardiac Arrest that is active but no longer recruiting, run by Brigham and Women's Hospital. The registered enrollment target is 50 participants, below the 1,478-participant average among 31 other Cardiac Arrest trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06423768, a study of Cardiac Arrest, is active but no longer recruiting, sponsored by Brigham and Women's Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this observational study is to determine whether specific advanced MRI measures are associated with functional outcomes in patients who are comatose after cardiac arrest. The main question\[s\] it aims to answer are: Aim 1: Determine if stimulus-based functional MRI (fMRI)-measured activations are independently associated with favorable neurological outcomes after cardiac arrest Aim 2: Determine if resting state functional MRI (rs-fMRI)-measured functional network connectivity is independently associated with favorable neurological outcomes after cardiac arrest. Aim 3: Determine if diffusion tensor imaging (DTI)-measured white matter integrity is associated with favorable neurological outcomes after cardiac arrest. Participants will undergo advanced MRI sequences at time of clinical MRI, and will be followed for 6 months post-arrest.
Primary Outcome
A standardized scale describing a patients overall level of independent function. Ranges from 1 (asymptomatic) to 5 (death). Levels 1-2 reflect patients who are functionally independent in their iADLs.
Conditions Studied
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2024-05-16 |
| Est. Completion | 2027-12-01 |
What the registry record for NCT06423768 still lists
NCT06423768 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,478-participant average among 31 other Cardiac Arrest trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Cardiac Arrest appearing as the primary indexed condition, and to 0 interventions.
NCT06423768 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06423768 about?
NCT06423768 is a clinical study titled "fMRI in CardiaC arrEst With Uncertain Prognosis". The goal of this observational study is to determine whether specific advanced MRI measures are associated with functional outcomes in patients who are comatose after cardiac arrest. The main question\[s\] it aims to answer are: Aim 1: Determine if stimulus-based functional MRI (fMRI)-measured acti...
What is the current status of trial NCT06423768?
This trial is currently active not recruiting. The enrollment target is 50 participants. The study started on 2024-05-16. Estimated completion is 2027-12-01.
What conditions does trial NCT06423768 study?
This clinical trial studies the following conditions: Cardiac Arrest.
Who is sponsoring clinical trial NCT06423768?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06423768 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiac Arrest
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06423768's enrollment target sits among peer trials
50 20th of 31 higher than 10 of 31 other Cardiac Arrest trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiac Arrest trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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