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Hypertension: full-pipeline trial registry
152 of 472 indexed Hypertension trials are currently recruiting.
Corpus placement: #8 of 28,707 conditions by registered trial count.
472 US clinical trials · 152 currently recruiting · #8 of 28,707 conditions by registered trial count
Hypertension: 472 US clinical trials tracked, 152 recruiting.
Hypertension is the subject of 472 registered US clinical trials on ClinicalTrials.gov, 152 of them currently open to new participants. 65 are in Phase 3-4 (later-stage) and 64 in Phase 1-2 (earlier-stage). The most active sponsor is Johns Hopkins University, running 15 of these trials.
Enrollment posture brief
Registry condition hypertension
OPEN 152 | RECR 32% | LATE 65 | EARLY 64 | RANK #8 | SPON 15
Volume-matched condition peers
Nearest open-share peer: Leukemia, Myeloid, Acute (32% recruiting · 31 trials)
Hypertension lists 152 open slots (32% of 472 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Hypertension on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Hypertension is recruiting below its size-band peers.
152 of 472 indexed trials (32.2%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Hypertension trials is spread across many organizations.
Johns Hopkins University accounts for 15 of 472 trials (3.2%). 195 distinct sponsors appear on at least one study for this condition label.
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Typical Hypertension enrolment sits around 168 participants.
Median target enrolment is 168 among the 471 trials that report a genuine target (sentinel values excluded). 170 of those (36.1%) plan for fewer than 100 participants.
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Hypertension research is mostly interventional.
407 interventional and 65 observational studies make up this index (86.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
472 total, page 1 of 10
Social Needs Screening and Chronic Diseases Study (WE CARE)
University of Massachusetts, Worcester
NCT06903897
Examining Digital Health Care Delivery Models Through Medicaid Collaborative
OSF Healthcare System
NCT05555095
Improving Hypertension Control in Safety-Net Settings: The Boston Hypertension Equity Alliance in Treatment
Boston Medical Center
NCT06948838
Precision Nudging for Hypertension Management: Observational Study
Lirio
NCT06354192
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Boehringer Ingelheim
NCT07064473
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
Alnylam Pharmaceuticals
NCT07181109
Community Park-Based Programs for Health Promotion: Fit2Play Prospective Cohort Study
Duke University
NCT06595251
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Duke University
NCT04278404
Study of the Progression of Chronic Cardiovascular Conditions
Prolaio
NCT07420907
Preventing Cognitive Decline by Reducing BP Target Trial
University of Texas Southwestern Medical Center
NCT05106036
Childhood-Onset Essential Hypertension Natural History Study
National Human Genome Research Institute (NHGRI)
NCT06778239
Community Intervention to Reduce CardiovascuLar Disease in Chicago
Northwestern University
NCT04755153
Diabetes and Heart Disease Risk in Blacks
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00001853
Penn Medicine Healthy Heart
University of Pennsylvania
NCT06062394
'Ai Pono Cooking Demonstrations
University of Hawaii
NCT06526650
Colorado Community Engagement Alliance
University of Colorado, Denver
NCT07440316
Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions
Massachusetts General Hospital
NCT06557005
Comparing Healthcare Visit Recording and Open Notes to Improve Chronic iLlness Care Experience in Older Adults
Dartmouth-Hitchcock Medical Center
NCT05955339
Blood Pressure Lowering Strategies to Eliminate Hypertension Disparities (BLESSED)
Tulane University
NCT06133322
Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT03374215
Community Park-Based Programs for Health Promotion: The Fit2Lead Prospective Cohort Study
Duke University
NCT06596265
Longitudinal Real-world Clinical Outcomes Study on Symplicity Renal Denervation
Medtronic Vascular
NCT07174622
Addressing Cardiometabolic Health In Populations Through Early Prevention in the Great Lakes Region Project 1 - Epidemiology (ACHIEVE P1-EPI)
Wayne State University
NCT06593496
Community Park-Based Programs for Health Promotion: Active Older Adults Prospective Cohort Study
Duke University
NCT06604650
The RADIANCE CED Study
ReCor Medical
NCT07231757
Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage
Zeenat Qureshi Stroke Institute
NCT06402968
Global Paradise System US Post Approval Study
ReCor Medical
NCT06297291
A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening)
Eli Lilly and Company
NCT06948422
SMBP Study: Improving High Blood Pressure in Older Adults With Multiple Chronic Diseases
Korey Kennelty
NCT06932029
Church-based Health Intervention to Eliminate Racial Inequalities in Cardiovascular Health
Tulane University
NCT06065098
Addressing Hypertension Care in Africa Program
Johns Hopkins University
NCT06986590
Bridging the Evidence-to-practice Gap
NYU Langone Health
NCT03713515
Community Engagement Alliance Against Disparities
Johns Hopkins University
NCT06607341
Military Health and Nutrition Examination Study
Pennington Biomedical Research Center
NCT06380322
Mobile Cued Adherence Therapy (mCAT) for Blood Pressure Medication
Chad Stecher@asu.edu
NCT06876233
Remote Patient Monitoring and Health Coaching vs. Usual Care for the Treatment of Hypertension
Stanford University
NCT05394766
Collaboration Oriented Approach to Controlling High Blood Pressure
Oregon Health and Science University
NCT06124716
Reducing Blood Pressure in Patients With High Cardiovascular Risk
University of Southern California
NCT05937685
Reach Out 2: Emergency Department-Initiated Hypertension Mobile Health Intervention Connecting Multiple Health Systems
Northwestern University
NCT06391073
Exercise Testing After Preeclampsia
Vanderbilt University Medical Center
NCT06741436
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
Orchestra BioMed
NCT06059638
CARBON: UAB Cardiovascular Research Biobank
University of Alabama at Birmingham
NCT05067231
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1
Eli Lilly and Company
NCT06948435
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2
Eli Lilly and Company
NCT06952530
The "Check, Monitor, Control Hypertension" Study is a 24-month Randomized Trial in Houston Targeting African Americans Aged 55+. It Combines Pharmacist Counseling and CHW Support to Improve Blood Pressure Control in Hypertension Management.
Texas Southern University
NCT07413159
Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial
University of Pittsburgh
NCT05655936
The Path to Optimal Black Maternal Heart Health: Comparing Two CVD Risk Reduction Interventions (Change of HEART)
Temple University
NCT05499507
A Cardiometabolic Health Program Linked With Clinical-Community Support and Mobile Health Telemonitoring to Reduce Health Disparities
Johns Hopkins University
NCT05321368
: Vascular Function in Health and Disease
Russell Richardson
NCT02966665
Medication Adherence Program
Tulane University
NCT05183763
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 39 |
| Phase 2 | 25 |
| Phase 3 | 37 |
| Phase 4 | 28 |
Top Sponsors
Named interventions
Most-linked intervention names on Hypertension records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Hypertension trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Hypertension page
472 registered trials, 152 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 152 Hypertension trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Johns Hopkins University sponsors the most Hypertension trials on record, review their full trial history before evaluating a specific study. See Johns Hopkins University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hypertension condition card totals 472 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.