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NCT06980623 · ClinicalTrials.gov registry record

Comparative Effectiveness of Tirzepatide vs Semaglutide in Participants With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction

A clinical trial of Heart Failure and Type 2 Diabetes, sponsored by Brigham and Women's Hospital.

Active
Registry status
26,000
Enrollment target
1
Study location

NCT06980623 is a study of Heart Failure and Type 2 Diabetes that is active but no longer recruiting, run by Brigham and Women's Hospital. The registered enrollment target is 26,000 participants, above the 1,984-participant average among 397 other Heart Failure trials with a reported enrollment target (1210% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT06980623, a study of Heart Failure and Type 2 Diabetes, is active but no longer recruiting, sponsored by Brigham and Women's Hospital.

ACTIVE NOT RECRUITING
Registry status
26,000 participants
Enrollment target
1
Study location

Study Summary

This cohort study aims to assess the comparative effectiveness of tirzepatide versus semaglutide with respect to cardiovascular events in patients with type 2 diabetes and heart failure with preserved ejection fraction.

Conditions Studied

Heart Failure Type 2 Diabetes

Interventions

  • DRUG Tirzepatide
  • DRUG Semaglutide

Study Locations (1)

Massachusetts

  • Brigham and Women's Hospital - Boston

Trial Details

FieldValue
Enrollment Target 26,000 participants
Start Date 2025-01-01
Est. Completion 2026-03-01

Sponsor

Brigham and Women's Hospital

937 total trials

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What the Registry Record Tells You About NCT06980623

The ClinicalTrials.gov registry entry for NCT06980623 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 26,000 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 1,984-participant average among 397 other Heart Failure trials with a reported enrollment target (1210% higher). The listed sponsor is Brigham and Women's Hospital, which has 937 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Heart Failure appearing as the primary indexed condition, and to 2 interventions - of which Tirzepatide is the first listed.

NCT06980623 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT06980623 about?

NCT06980623 is a clinical study titled "Comparative Effectiveness of Tirzepatide vs Semaglutide in Participants With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction". This cohort study aims to assess the comparative effectiveness of tirzepatide versus semaglutide with respect to cardiovascular events in patients with type 2 diabetes and heart failure with preserved ejection fraction.

What is the current status of trial NCT06980623?

This trial is currently active not recruiting. The enrollment target is 26,000 participants. The study started on 2025-01-01. Estimated completion is 2026-03-01.

What conditions does trial NCT06980623 study?

This clinical trial studies the following conditions: Heart Failure, Type 2 Diabetes.

What interventions are being tested in trial NCT06980623?

The interventions under investigation include: Tirzepatide (DRUG), Semaglutide (DRUG).

Who is sponsoring clinical trial NCT06980623?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06980623 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.