Brigham and Women's Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Brigham and Women's Hospital sits in the top decile of US sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count).
Brigham and Women's Hospital: 937 sponsored US clinical trials, 145 recruiting.
Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Type 2 Diabetes, with 13 trials.
Top-decile sponsor footprint
Brigham and Women's Hospital ranks in the top decile of sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
608 of 677 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
937 total, page 3 of 19
MAGIC AKI: Magnesium for the Prevention of HIOC-Associated AKI
NCT05730816
Dietary Intervention to Mitigate Adverse Consequences of Night Work
NCT04868526
The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease
NCT07222683
Randomized Controlled Trial of Alert-Based Computerized Decision Support for Patients With Peripheral Artery Disease Not Prescribed Lipid-Lowering Therapy
NCT06300450
PREventing Pain After Surgery
NCT05306665
Efficacy of Suvorexant in the Treatment of Insomnia in Midlife Women With Pre-Diabetes
NCT05593653
Molecular Imaging of Myocardial Fibrosis in Cardiac Amyloidosis
NCT05619302
Testing Effects of Melatonin on Uterine Contractions in Women
NCT05358834
SmartSteps: A Context-Aware, PrEP Adherence Intervention for Individuals With Substance Use Disorder
NCT05378399
Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study
NCT05030545
Microdevice In Ovarian, Fallopian Tube, And Peritoneal Cancer
NCT04701645
Menstrual-phase-dependent Differences in Response to Sleep Loss
NCT05381532
Angiotensin-Neprilysin Inhibition in Hemodialysis Initiation
NCT05498181
PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
NCT05390892
Pre-emptive Prevention for Patients at High Risk for Hospital-onset Clostridioides Difficile
NCT05389904
Atomoxetine and DAW2022 on OSA Severity
NCT05350215
The Impact of Pcsk-9 Inhibition on PET CFR in Patients at High CV Risk
NCT05152888
Real-time Symptom Monitoring Using ePROs to Prevent Adverse Events During Care Transitions
NCT05282654
Pain Alleviation With Testosterone in Opioid-Induced Hypogonadism
NCT04798469
Anti-Inflammatory Treatment of Uremic Cardiomyopathy With Colchicine
NCT04500665
Assessing the Burden of Perioperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
NCT04880265
Detection of Small Fiber Neuropathy Using Skin Properties
NCT04759443
Endoscopic Ultrasound Shear Wave Elastography in Patients With Non-alcoholic Fatty Liver Disease
NCT05728697
CONFIRM: Magnetic Resonance Guided Radiation Therapy
NCT04368702
Defibrotide for the Treatment of Severe COVID-19
NCT04652115
Jump: MR Simulation For Radiation Therapy Master Protocol
NCT04545957
AMI Construction in Lower Extremity Residual Limbs
NCT04063592
Treatment Response Assessment Maps to Delineate Necrosis From Tumor After Stereotactic Radiation in Brain Metastases
NCT04033497
Screening Magnetic Resonance Imaging of the Brain in Patients With Breast Cancer
NCT04030507
A Novel Approach to Upper Extremity Amputation to Augment Volitional Control and Restore Proprioception
NCT03882073
Pharmacological Activation of HMN for OSA Aim 2
NCT03858751
Low Intensity Focused Ultrasound Epilepsy: A Pilot Trial
NCT03868293
Computerized Decision Support for Prevention of VTE in Hospitalized Medical Patients Across the Continuum of Care (DC-eALERT)
NCT03728166
Alvimopan Versus Placebo in Patients Undergoing Radical Cystectomy on an Enhanced Recovery Protocol
NCT03216525
Image Guided VATS vs. VATS Resection
NCT03623958
Brain Connectivity in Depression
NCT03276793
Home Hospital for Suddenly Ill Adults
NCT03524222
Molecular Imaging of NET Using [C-11]MRB-PET in MS
NCT03207464
PET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases
NCT02649985
Molecular Imaging of Primary Amyloid Cardiomyopathy
NCT02641145
MRI-Guided Cryoablation to Alleviate Pain in Head, Neck and Spine
NCT01788410
Vascularized Composite Allotransplantation for Multiple Extremity Amputations
NCT01293214
TRANSCRIBE (Transcriptomic Analysis of Left Ventricular Gene Expression)
NCT00985049
Identification of Genomic Predictors of Adverse Events After Cardiac Surgery
NCT01258231
Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) Study
NCT01177618
Emulation of the KEYNOTE-042 (NCT02220894) Trial Using Specialty Oncology Electronic Health Records Databases
NCT07485179
Emulation of the CheckMate 017/057 (NCT01642004 and NCT01673867) Trials Using Specialty Oncology Electronic Health Records Databases
NCT07485166
TMS With Real-time E-field and EEG Source Imaging
NCT06645613
Emulation of the REWIND Cardiovascular Outcomes Trial in Healthcare Claims Data.
NCT07417631
The Use of Artificial Intelligence Generated Contours in Radiation Planning of the Prostate Brachytherapy
NCT06964412
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 90 |
| Phase 2 | 107 |
| Phase 3 | 47 |
| Phase 4 | 77 |
Therapeutic Areas
What is open in the Brigham and Women's Hospital pipeline
145 recruiting of 937 indexed (15% open); 608 completed (65%).
Phase mix: 124 late (III/IV) vs 197 early (I/II) (early-phase heavy).
Top condition: Type 2 Diabetes (13 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Brigham and Women's Hospital: open-pipeline peers nationwide
Peers matched on 937 registered trials and 15% open enrollment, not the therapeutic-area sidebar.
Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 937 trials (± recruiting share)
- Columbia University · 958 trials · 18% recruiting
- Hoffmann-La Roche · 909 trials · 8% recruiting
- University of Minnesota · 966 trials · 19% recruiting
- University of California, Los Angeles · 897 trials · 18% recruiting
Sponsors near 15% open enrollment (± trial volume)
- Incyte Corporation · 15% recruiting · 239 trials
- Northwestern University · 15% recruiting · 1,209 trials
- Nationwide Children's Hospital · 15% recruiting · 188 trials
- University of Michigan Rogel Cancer Center · 15% recruiting · 292 trials
Related
What to do with this Brigham and Women's Hospital page
937 registered trials is a research-attention snapshot, not an endorsement of Brigham and Women's Hospital or any single study.
- 145 of Brigham and Women's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Type 2 Diabetes is the condition Brigham and Women's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Type 2 Diabetes trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Brigham and Women's Hospital pipeline card: 937 registered trials from official public datasets.Report a data error.