Brigham and Women's Hospital

937 total trials 145 currently recruiting 608 completed

Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hypertension, with 12 trials.

Trial Pipeline

937 total, page 3 of 19

RECRUITING Phase 2

MAGIC AKI: Magnesium for the Prevention of HIOC-Associated AKI

NCT05730816

RECRUITING NA

Dietary Intervention to Mitigate Adverse Consequences of Night Work

NCT04868526

RECRUITING

The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease

NCT07222683

RECRUITING NA

Randomized Controlled Trial of Alert-Based Computerized Decision Support for Patients With Peripheral Artery Disease Not Prescribed Lipid-Lowering Therapy

NCT06300450

RECRUITING NA

PREventing Pain After Surgery

NCT05306665

RECRUITING Phase 4

Efficacy of Suvorexant in the Treatment of Insomnia in Midlife Women With Pre-Diabetes

NCT05593653

RECRUITING Phase 3

Molecular Imaging of Myocardial Fibrosis in Cardiac Amyloidosis

NCT05619302

RECRUITING NA

Testing Effects of Melatonin on Uterine Contractions in Women

NCT05358834

RECRUITING Phase 3

SmartSteps: A Context-Aware, PrEP Adherence Intervention for Individuals With Substance Use Disorder

NCT05378399

RECRUITING Phase 4

Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study

NCT05030545

RECRUITING Phase 1

Microdevice In Ovarian, Fallopian Tube, And Peritoneal Cancer

NCT04701645

RECRUITING NA

Menstrual-phase-dependent Differences in Response to Sleep Loss

NCT05381532

RECRUITING Phase 2

Angiotensin-Neprilysin Inhibition in Hemodialysis Initiation

NCT05498181

RECRUITING Phase 4

PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes

NCT05390892

RECRUITING NA

Pre-emptive Prevention for Patients at High Risk for Hospital-onset Clostridioides Difficile

NCT05389904

RECRUITING Phase 1

Atomoxetine and DAW2022 on OSA Severity

NCT05350215

RECRUITING Phase 4

The Impact of Pcsk-9 Inhibition on PET CFR in Patients at High CV Risk

NCT05152888

RECRUITING NA

Real-time Symptom Monitoring Using ePROs to Prevent Adverse Events During Care Transitions

NCT05282654

RECRUITING Phase 2

Pain Alleviation With Testosterone in Opioid-Induced Hypogonadism

NCT04798469

RECRUITING Phase 2

Anti-Inflammatory Treatment of Uremic Cardiomyopathy With Colchicine

NCT04500665

RECRUITING

Assessing the Burden of Perioperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery

NCT04880265

RECRUITING

Detection of Small Fiber Neuropathy Using Skin Properties

NCT04759443

RECRUITING

Endoscopic Ultrasound Shear Wave Elastography in Patients With Non-alcoholic Fatty Liver Disease

NCT05728697

RECRUITING NA

CONFIRM: Magnetic Resonance Guided Radiation Therapy

NCT04368702

RECRUITING Phase 2

Defibrotide for the Treatment of Severe COVID-19

NCT04652115

RECRUITING NA

Jump: MR Simulation For Radiation Therapy Master Protocol

NCT04545957

RECRUITING NA

AMI Construction in Lower Extremity Residual Limbs

NCT04063592

RECRUITING NA

Treatment Response Assessment Maps to Delineate Necrosis From Tumor After Stereotactic Radiation in Brain Metastases

NCT04033497

RECRUITING NA

Screening Magnetic Resonance Imaging of the Brain in Patients With Breast Cancer

NCT04030507

RECRUITING NA

A Novel Approach to Upper Extremity Amputation to Augment Volitional Control and Restore Proprioception

NCT03882073

RECRUITING Phase 1

Pharmacological Activation of HMN for OSA Aim 2

NCT03858751

RECRUITING NA

Low Intensity Focused Ultrasound Epilepsy: A Pilot Trial

NCT03868293

RECRUITING NA

Computerized Decision Support for Prevention of VTE in Hospitalized Medical Patients Across the Continuum of Care (DC-eALERT)

NCT03728166

RECRUITING Phase 3

Alvimopan Versus Placebo in Patients Undergoing Radical Cystectomy on an Enhanced Recovery Protocol

NCT03216525

RECRUITING NA

Image Guided VATS vs. VATS Resection

NCT03623958

RECRUITING NA

Brain Connectivity in Depression

NCT03276793

RECRUITING NA

Home Hospital for Suddenly Ill Adults

NCT03524222

RECRUITING Phase 1

Molecular Imaging of NET Using [C-11]MRB-PET in MS

NCT03207464

RECRUITING Phase 1

PET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases

NCT02649985

RECRUITING NA

Molecular Imaging of Primary Amyloid Cardiomyopathy

NCT02641145

RECRUITING

MRI-Guided Cryoablation to Alleviate Pain in Head, Neck and Spine

NCT01788410

RECRUITING NA

Vascularized Composite Allotransplantation for Multiple Extremity Amputations

NCT01293214

RECRUITING

TRANSCRIBE (Transcriptomic Analysis of Left Ventricular Gene Expression)

NCT00985049

RECRUITING

Identification of Genomic Predictors of Adverse Events After Cardiac Surgery

NCT01258231

RECRUITING

Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) Study

NCT01177618

ACTIVE NOT RECRUITING

Emulation of the KEYNOTE-042 (NCT02220894) Trial Using Specialty Oncology Electronic Health Records Databases

NCT07485179

ACTIVE NOT RECRUITING

Emulation of the CheckMate 017/057 (NCT01642004 and NCT01673867) Trials Using Specialty Oncology Electronic Health Records Databases

NCT07485166

ACTIVE NOT RECRUITING NA

TMS With Real-time E-field and EEG Source Imaging

NCT06645613

ACTIVE NOT RECRUITING

Emulation of the REWIND Cardiovascular Outcomes Trial in Healthcare Claims Data.

NCT07417631

ACTIVE NOT RECRUITING NA

The Use of Artificial Intelligence Generated Contours in Radiation Planning of the Prostate Brachytherapy

NCT06964412

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Phase Distribution

PhaseTrial count
Phase 1 90
Phase 2 107
Phase 3 47
Phase 4 77

What the Pipeline for Brigham and Women's Hospital Shows

According to the ClinicalTrials.gov registry, Brigham and Women's Hospital is linked to 937 US clinical trials across every stage of research activity. Of those, 145 studies are currently recruiting, about 15% of the sponsor's indexed portfolio, and 608 are already marked complete, representing roughly 65% of the total.

The phase mix for Brigham and Women's Hospital reports 124 late-stage studies (Phase 3 and Phase 4 combined) and 197 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Brigham and Women's Hospital is Hypertension with 12 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.