Brigham and Women's Hospital
Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hypertension, with 12 trials.
Trial Pipeline
937 total, page 3 of 19
MAGIC AKI: Magnesium for the Prevention of HIOC-Associated AKI
NCT05730816
Dietary Intervention to Mitigate Adverse Consequences of Night Work
NCT04868526
The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease
NCT07222683
Randomized Controlled Trial of Alert-Based Computerized Decision Support for Patients With Peripheral Artery Disease Not Prescribed Lipid-Lowering Therapy
NCT06300450
PREventing Pain After Surgery
NCT05306665
Efficacy of Suvorexant in the Treatment of Insomnia in Midlife Women With Pre-Diabetes
NCT05593653
Molecular Imaging of Myocardial Fibrosis in Cardiac Amyloidosis
NCT05619302
Testing Effects of Melatonin on Uterine Contractions in Women
NCT05358834
SmartSteps: A Context-Aware, PrEP Adherence Intervention for Individuals With Substance Use Disorder
NCT05378399
Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study
NCT05030545
Microdevice In Ovarian, Fallopian Tube, And Peritoneal Cancer
NCT04701645
Menstrual-phase-dependent Differences in Response to Sleep Loss
NCT05381532
Angiotensin-Neprilysin Inhibition in Hemodialysis Initiation
NCT05498181
PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
NCT05390892
Pre-emptive Prevention for Patients at High Risk for Hospital-onset Clostridioides Difficile
NCT05389904
Atomoxetine and DAW2022 on OSA Severity
NCT05350215
The Impact of Pcsk-9 Inhibition on PET CFR in Patients at High CV Risk
NCT05152888
Real-time Symptom Monitoring Using ePROs to Prevent Adverse Events During Care Transitions
NCT05282654
Pain Alleviation With Testosterone in Opioid-Induced Hypogonadism
NCT04798469
Anti-Inflammatory Treatment of Uremic Cardiomyopathy With Colchicine
NCT04500665
Assessing the Burden of Perioperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
NCT04880265
Detection of Small Fiber Neuropathy Using Skin Properties
NCT04759443
Endoscopic Ultrasound Shear Wave Elastography in Patients With Non-alcoholic Fatty Liver Disease
NCT05728697
CONFIRM: Magnetic Resonance Guided Radiation Therapy
NCT04368702
Defibrotide for the Treatment of Severe COVID-19
NCT04652115
Jump: MR Simulation For Radiation Therapy Master Protocol
NCT04545957
AMI Construction in Lower Extremity Residual Limbs
NCT04063592
Treatment Response Assessment Maps to Delineate Necrosis From Tumor After Stereotactic Radiation in Brain Metastases
NCT04033497
Screening Magnetic Resonance Imaging of the Brain in Patients With Breast Cancer
NCT04030507
A Novel Approach to Upper Extremity Amputation to Augment Volitional Control and Restore Proprioception
NCT03882073
Pharmacological Activation of HMN for OSA Aim 2
NCT03858751
Low Intensity Focused Ultrasound Epilepsy: A Pilot Trial
NCT03868293
Computerized Decision Support for Prevention of VTE in Hospitalized Medical Patients Across the Continuum of Care (DC-eALERT)
NCT03728166
Alvimopan Versus Placebo in Patients Undergoing Radical Cystectomy on an Enhanced Recovery Protocol
NCT03216525
Image Guided VATS vs. VATS Resection
NCT03623958
Brain Connectivity in Depression
NCT03276793
Home Hospital for Suddenly Ill Adults
NCT03524222
Molecular Imaging of NET Using [C-11]MRB-PET in MS
NCT03207464
PET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases
NCT02649985
Molecular Imaging of Primary Amyloid Cardiomyopathy
NCT02641145
MRI-Guided Cryoablation to Alleviate Pain in Head, Neck and Spine
NCT01788410
Vascularized Composite Allotransplantation for Multiple Extremity Amputations
NCT01293214
TRANSCRIBE (Transcriptomic Analysis of Left Ventricular Gene Expression)
NCT00985049
Identification of Genomic Predictors of Adverse Events After Cardiac Surgery
NCT01258231
Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) Study
NCT01177618
Emulation of the KEYNOTE-042 (NCT02220894) Trial Using Specialty Oncology Electronic Health Records Databases
NCT07485179
Emulation of the CheckMate 017/057 (NCT01642004 and NCT01673867) Trials Using Specialty Oncology Electronic Health Records Databases
NCT07485166
TMS With Real-time E-field and EEG Source Imaging
NCT06645613
Emulation of the REWIND Cardiovascular Outcomes Trial in Healthcare Claims Data.
NCT07417631
The Use of Artificial Intelligence Generated Contours in Radiation Planning of the Prostate Brachytherapy
NCT06964412
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 90 |
| Phase 2 | 107 |
| Phase 3 | 47 |
| Phase 4 | 77 |
Therapeutic Areas
What the Pipeline for Brigham and Women's Hospital Shows
According to the ClinicalTrials.gov registry, Brigham and Women's Hospital is linked to 937 US clinical trials across every stage of research activity. Of those, 145 studies are currently recruiting, about 15% of the sponsor's indexed portfolio, and 608 are already marked complete, representing roughly 65% of the total.
The phase mix for Brigham and Women's Hospital reports 124 late-stage studies (Phase 3 and Phase 4 combined) and 197 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Brigham and Women's Hospital is Hypertension with 12 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.