Brigham and Women's Hospital

937 total trials 145 currently recruiting 608 completed

Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hypertension, with 12 trials.

Trial Pipeline

937 total, page 5 of 19

ACTIVE NOT RECRUITING Phase 2

Deferoxamine for the Prevention of Cardiac Surgery-Associated Acute Kidney Injury

NCT04633889

ACTIVE NOT RECRUITING Phase 2

Standing Tall (Yima Nkqo)

NCT04568460

ACTIVE NOT RECRUITING NA

Serial Brain MRI in Hospitalized Preterm Infants

NCT06052865

ACTIVE NOT RECRUITING Phase 2

INTREPId (INTermediate Risk Erection PreservatIon Trial)

NCT04025372

ACTIVE NOT RECRUITING Early Phase 1

18Fluorine-Fluciclovine PET/CT for Staging Muscle Invasive Bladder Cancer Preceding Radical Cystectomy

NCT04018053

ACTIVE NOT RECRUITING NA

Targeting Human Milk Fortification to Improve Preterm Infant Growth and Brain Development

NCT03977259

ACTIVE NOT RECRUITING Phase 4

The Effects of Dupilumab on Allergic Contact Dermatitis

NCT03935971

ACTIVE NOT RECRUITING

Transcutaneous Carbon Dioxide Monitoring in Neonates Receiving Therapeutic Hypothermia for Neonatal Encephalopathy

NCT04603547

ACTIVE NOT RECRUITING NA

VITamin D and OmegA-3 TriaL: Interrelationship of Vitamin D and Vitamin K on Bone (VITAL)

NCT04573946

ACTIVE NOT RECRUITING Phase 2

Safety and Efficacy Study of Inhaled Carbon Monoxide to Treat Acute Respiratory Distress Syndrome (ARDS)

NCT03799874

ACTIVE NOT RECRUITING NA

Cranberry Tablets Versus Nitrofurantoin Prophylaxis for Urinary Tract Infection Prevention After Urogynecologic Surgery

NCT03522961

ACTIVE NOT RECRUITING

Prospective Phenotyping of Autonomous Aldosterone Secretion

NCT03484130

ACTIVE NOT RECRUITING

Fertility, Hypercoagulability, and Inflammation (FREYA) Registry

NCT04537416

ACTIVE NOT RECRUITING

Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder

NCT03336918

ACTIVE NOT RECRUITING NA

The Brain Health Champion Study

NCT03772977

ACTIVE NOT RECRUITING NA

Lysine-specific Demethylase 1 and Salt-sensitivity in Humans

NCT03029806

ACTIVE NOT RECRUITING NA

BMI-based Vitamins in Obese Pregnant Women

NCT02802566

ACTIVE NOT RECRUITING NA

Successful Aging and Enrichment (SAGE)

NCT05128396

ACTIVE NOT RECRUITING NA

Effects of Vitamin D and Marine Omega-3 Fatty Acids on Anemia

NCT01632761

ACTIVE NOT RECRUITING Phase 3

VITAL Rhythm Study

NCT02178410

ACTIVE NOT RECRUITING NA

Vitamin D and Omega-3 Hypertension Trial (VITAL Hypertension)

NCT01653678

ACTIVE NOT RECRUITING

Objective Assessment of the Effects of Shift Work on Drowsiness and Driving Impairment in Hospital Staff

NCT01672489

ACTIVE NOT RECRUITING Phase 1

Caveolin-1 and Vascular Dysfunction

NCT01426529

ACTIVE NOT RECRUITING NA

LungVITamin D and OmegA-3 Trial (lungVITAL)

NCT01728571

ACTIVE NOT RECRUITING Phase 3

Vitamin D and Omega-3 Trial (VITAL)

NCT01169259

ACTIVE NOT RECRUITING NA

Effects of Vitamin D and Omega-3 Fatty Acids on Infectious Diseases and hCAP18 (VITAL Infection)

NCT01758081

ACTIVE NOT RECRUITING NA

Comparing Surgery Versus Standard Physical Therapy in Treating People With a Meniscal Tear and Osteoarthritis

NCT00597012

ACTIVE NOT RECRUITING

Examining the Genetic Factors That May Cause Chronic Obstructive Pulmonary Disease (COPD)

NCT00608764

ACTIVE NOT RECRUITING

PRE-DETERMINE Cohort Study

NCT01114269

ACTIVE NOT RECRUITING

Brigham and Women's Rheumatoid Arthritis Sequential Study

NCT01793103

NOT YET RECRUITING Phase 2

Dynamic Treatment Regimes for Opioid Use Disorder

NCT07011758

NOT YET RECRUITING NA

Computerized Decision Support to Prevent Stroke in Atrial Fibrillation

NCT06355986

NOT YET RECRUITING NA

Does Circadian Misalignment Have Sex-Specific Effects on Metabolism?

NCT07441265

NOT YET RECRUITING Early Phase 1

Pilot Trial of Xylitol for C. Difficile De-Colonization in Patients With Inflammatory Bowel Disease

NCT06799039

NOT YET RECRUITING Phase 3

STENT X: a Randomized Trial to Assess Stent-free Radical Cystectomy

NCT07655284

NOT YET RECRUITING NA

Movie-Watching Functional MRI for Mapping Brain Function in Neurosurgical Patients

NCT07650994

NOT YET RECRUITING NA

Endoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss

NCT06299644

NOT YET RECRUITING Phase 4

Use of Fidaxomicin Compared to Vancomycin for Decolonization of C. Difficile in Patients With Inflammatory Bowel Disease

NCT06794944

NOT YET RECRUITING NA

Korus: a Device to Prevent Sudden Unexpected Death in Epilepsy (SUDEP)

NCT06135285

NOT YET RECRUITING Phase 3

Assessing Suzetrigine for Pain Reduction Following Ureteroscopic Surgery

NCT07654296

NOT YET RECRUITING Phase 1

Xylitol Use for Decolonization of C. Difficile in Patients With IBD

NCT05852587

NOT YET RECRUITING Phase 1

Ropeginterferon for High Risk JAK2 Clonal Hematopoiesis

NCT07249840

NOT YET RECRUITING Phase 1

Sonication-based OCD Neurosurgical Intervention Via Capsulotomy

NCT06131502

NOT YET RECRUITING Phase 1

NAD Augmentation to Prevent or Reverse Alzheimer's Disease in People With Down Syndrome

NCT07278492

NOT YET RECRUITING Phase 2

CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic Shock

NCT07461961

NOT YET RECRUITING Early Phase 1

Impacts of Opioids on Respiratory Drive During Sleep

NCT06854211

NOT YET RECRUITING NA

Using Virtual Reality to Teach Mindfulness to People With Migraine

NCT07599228

NOT YET RECRUITING NA

Improving the Quality of Care for Asthma Patients at Risk of Exacerbations

NCT06596512

NOT YET RECRUITING Phase 2

Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder

NCT07296094

NOT YET RECRUITING Phase 1

Sparsentan for the Treatment of VEGF Signaling Pathway Inhibitor-Associated Proteinuria

NCT07224776

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Phase Distribution

PhaseTrial count
Phase 1 90
Phase 2 107
Phase 3 47
Phase 4 77

What the Pipeline for Brigham and Women's Hospital Shows

According to the ClinicalTrials.gov registry, Brigham and Women's Hospital is linked to 937 US clinical trials across every stage of research activity. Of those, 145 studies are currently recruiting, about 15% of the sponsor's indexed portfolio, and 608 are already marked complete, representing roughly 65% of the total.

The phase mix for Brigham and Women's Hospital reports 124 late-stage studies (Phase 3 and Phase 4 combined) and 197 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Brigham and Women's Hospital is Hypertension with 12 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.