Brigham and Women's Hospital
Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hypertension, with 12 trials.
Trial Pipeline
937 total, page 5 of 19
Deferoxamine for the Prevention of Cardiac Surgery-Associated Acute Kidney Injury
NCT04633889
Standing Tall (Yima Nkqo)
NCT04568460
Serial Brain MRI in Hospitalized Preterm Infants
NCT06052865
INTREPId (INTermediate Risk Erection PreservatIon Trial)
NCT04025372
18Fluorine-Fluciclovine PET/CT for Staging Muscle Invasive Bladder Cancer Preceding Radical Cystectomy
NCT04018053
Targeting Human Milk Fortification to Improve Preterm Infant Growth and Brain Development
NCT03977259
The Effects of Dupilumab on Allergic Contact Dermatitis
NCT03935971
Transcutaneous Carbon Dioxide Monitoring in Neonates Receiving Therapeutic Hypothermia for Neonatal Encephalopathy
NCT04603547
VITamin D and OmegA-3 TriaL: Interrelationship of Vitamin D and Vitamin K on Bone (VITAL)
NCT04573946
Safety and Efficacy Study of Inhaled Carbon Monoxide to Treat Acute Respiratory Distress Syndrome (ARDS)
NCT03799874
Cranberry Tablets Versus Nitrofurantoin Prophylaxis for Urinary Tract Infection Prevention After Urogynecologic Surgery
NCT03522961
Prospective Phenotyping of Autonomous Aldosterone Secretion
NCT03484130
Fertility, Hypercoagulability, and Inflammation (FREYA) Registry
NCT04537416
Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder
NCT03336918
The Brain Health Champion Study
NCT03772977
Lysine-specific Demethylase 1 and Salt-sensitivity in Humans
NCT03029806
BMI-based Vitamins in Obese Pregnant Women
NCT02802566
Successful Aging and Enrichment (SAGE)
NCT05128396
Effects of Vitamin D and Marine Omega-3 Fatty Acids on Anemia
NCT01632761
VITAL Rhythm Study
NCT02178410
Vitamin D and Omega-3 Hypertension Trial (VITAL Hypertension)
NCT01653678
Objective Assessment of the Effects of Shift Work on Drowsiness and Driving Impairment in Hospital Staff
NCT01672489
Caveolin-1 and Vascular Dysfunction
NCT01426529
LungVITamin D and OmegA-3 Trial (lungVITAL)
NCT01728571
Vitamin D and Omega-3 Trial (VITAL)
NCT01169259
Effects of Vitamin D and Omega-3 Fatty Acids on Infectious Diseases and hCAP18 (VITAL Infection)
NCT01758081
Comparing Surgery Versus Standard Physical Therapy in Treating People With a Meniscal Tear and Osteoarthritis
NCT00597012
Examining the Genetic Factors That May Cause Chronic Obstructive Pulmonary Disease (COPD)
NCT00608764
PRE-DETERMINE Cohort Study
NCT01114269
Brigham and Women's Rheumatoid Arthritis Sequential Study
NCT01793103
Dynamic Treatment Regimes for Opioid Use Disorder
NCT07011758
Computerized Decision Support to Prevent Stroke in Atrial Fibrillation
NCT06355986
Does Circadian Misalignment Have Sex-Specific Effects on Metabolism?
NCT07441265
Pilot Trial of Xylitol for C. Difficile De-Colonization in Patients With Inflammatory Bowel Disease
NCT06799039
STENT X: a Randomized Trial to Assess Stent-free Radical Cystectomy
NCT07655284
Movie-Watching Functional MRI for Mapping Brain Function in Neurosurgical Patients
NCT07650994
Endoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss
NCT06299644
Use of Fidaxomicin Compared to Vancomycin for Decolonization of C. Difficile in Patients With Inflammatory Bowel Disease
NCT06794944
Korus: a Device to Prevent Sudden Unexpected Death in Epilepsy (SUDEP)
NCT06135285
Assessing Suzetrigine for Pain Reduction Following Ureteroscopic Surgery
NCT07654296
Xylitol Use for Decolonization of C. Difficile in Patients With IBD
NCT05852587
Ropeginterferon for High Risk JAK2 Clonal Hematopoiesis
NCT07249840
Sonication-based OCD Neurosurgical Intervention Via Capsulotomy
NCT06131502
NAD Augmentation to Prevent or Reverse Alzheimer's Disease in People With Down Syndrome
NCT07278492
CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic Shock
NCT07461961
Impacts of Opioids on Respiratory Drive During Sleep
NCT06854211
Using Virtual Reality to Teach Mindfulness to People With Migraine
NCT07599228
Improving the Quality of Care for Asthma Patients at Risk of Exacerbations
NCT06596512
Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder
NCT07296094
Sparsentan for the Treatment of VEGF Signaling Pathway Inhibitor-Associated Proteinuria
NCT07224776
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 90 |
| Phase 2 | 107 |
| Phase 3 | 47 |
| Phase 4 | 77 |
Therapeutic Areas
What the Pipeline for Brigham and Women's Hospital Shows
According to the ClinicalTrials.gov registry, Brigham and Women's Hospital is linked to 937 US clinical trials across every stage of research activity. Of those, 145 studies are currently recruiting, about 15% of the sponsor's indexed portfolio, and 608 are already marked complete, representing roughly 65% of the total.
The phase mix for Brigham and Women's Hospital reports 124 late-stage studies (Phase 3 and Phase 4 combined) and 197 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Brigham and Women's Hospital is Hypertension with 12 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.