Brigham and Women's Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Brigham and Women's Hospital sits in the top decile of US sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count).
Brigham and Women's Hospital: 937 sponsored US clinical trials, 145 recruiting.
Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Type 2 Diabetes, with 13 trials.
Top-decile sponsor footprint
Brigham and Women's Hospital ranks in the top decile of sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
608 of 677 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
937 total, page 5 of 19
Deferoxamine for the Prevention of Cardiac Surgery-Associated Acute Kidney Injury
NCT04633889
Standing Tall (Yima Nkqo)
NCT04568460
Serial Brain MRI in Hospitalized Preterm Infants
NCT06052865
INTREPId (INTermediate Risk Erection PreservatIon Trial)
NCT04025372
18Fluorine-Fluciclovine PET/CT for Staging Muscle Invasive Bladder Cancer Preceding Radical Cystectomy
NCT04018053
Targeting Human Milk Fortification to Improve Preterm Infant Growth and Brain Development
NCT03977259
The Effects of Dupilumab on Allergic Contact Dermatitis
NCT03935971
Transcutaneous Carbon Dioxide Monitoring in Neonates Receiving Therapeutic Hypothermia for Neonatal Encephalopathy
NCT04603547
VITamin D and OmegA-3 TriaL: Interrelationship of Vitamin D and Vitamin K on Bone (VITAL)
NCT04573946
Safety and Efficacy Study of Inhaled Carbon Monoxide to Treat Acute Respiratory Distress Syndrome (ARDS)
NCT03799874
Cranberry Tablets Versus Nitrofurantoin Prophylaxis for Urinary Tract Infection Prevention After Urogynecologic Surgery
NCT03522961
Prospective Phenotyping of Autonomous Aldosterone Secretion
NCT03484130
Fertility, Hypercoagulability, and Inflammation (FREYA) Registry
NCT04537416
Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder
NCT03336918
The Brain Health Champion Study
NCT03772977
Lysine-specific Demethylase 1 and Salt-sensitivity in Humans
NCT03029806
BMI-based Vitamins in Obese Pregnant Women
NCT02802566
Successful Aging and Enrichment (SAGE)
NCT05128396
Effects of Vitamin D and Marine Omega-3 Fatty Acids on Anemia
NCT01632761
VITAL Rhythm Study
NCT02178410
Vitamin D and Omega-3 Hypertension Trial (VITAL Hypertension)
NCT01653678
Objective Assessment of the Effects of Shift Work on Drowsiness and Driving Impairment in Hospital Staff
NCT01672489
Caveolin-1 and Vascular Dysfunction
NCT01426529
LungVITamin D and OmegA-3 Trial (lungVITAL)
NCT01728571
Vitamin D and Omega-3 Trial (VITAL)
NCT01169259
Effects of Vitamin D and Omega-3 Fatty Acids on Infectious Diseases and hCAP18 (VITAL Infection)
NCT01758081
Comparing Surgery Versus Standard Physical Therapy in Treating People With a Meniscal Tear and Osteoarthritis
NCT00597012
Examining the Genetic Factors That May Cause Chronic Obstructive Pulmonary Disease (COPD)
NCT00608764
PRE-DETERMINE Cohort Study
NCT01114269
Brigham and Women's Rheumatoid Arthritis Sequential Study
NCT01793103
Dynamic Treatment Regimes for Opioid Use Disorder
NCT07011758
Computerized Decision Support to Prevent Stroke in Atrial Fibrillation
NCT06355986
Does Circadian Misalignment Have Sex-Specific Effects on Metabolism?
NCT07441265
Pilot Trial of Xylitol for C. Difficile De-Colonization in Patients With Inflammatory Bowel Disease
NCT06799039
STENT X: a Randomized Trial to Assess Stent-free Radical Cystectomy
NCT07655284
Movie-Watching Functional MRI for Mapping Brain Function in Neurosurgical Patients
NCT07650994
Endoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss
NCT06299644
Use of Fidaxomicin Compared to Vancomycin for Decolonization of C. Difficile in Patients With Inflammatory Bowel Disease
NCT06794944
Korus: a Device to Prevent Sudden Unexpected Death in Epilepsy (SUDEP)
NCT06135285
Assessing Suzetrigine for Pain Reduction Following Ureteroscopic Surgery
NCT07654296
Xylitol Use for Decolonization of C. Difficile in Patients With IBD
NCT05852587
Ropeginterferon for High Risk JAK2 Clonal Hematopoiesis
NCT07249840
Sonication-based OCD Neurosurgical Intervention Via Capsulotomy
NCT06131502
NAD Augmentation to Prevent or Reverse Alzheimer's Disease in People With Down Syndrome
NCT07278492
CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic Shock
NCT07461961
Impacts of Opioids on Respiratory Drive During Sleep
NCT06854211
Using Virtual Reality to Teach Mindfulness to People With Migraine
NCT07599228
Improving the Quality of Care for Asthma Patients at Risk of Exacerbations
NCT06596512
Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder
NCT07296094
Sparsentan for the Treatment of VEGF Signaling Pathway Inhibitor-Associated Proteinuria
NCT07224776
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 90 |
| Phase 2 | 107 |
| Phase 3 | 47 |
| Phase 4 | 77 |
Therapeutic Areas
What is open in the Brigham and Women's Hospital pipeline
145 recruiting of 937 indexed (15% open); 608 completed (65%).
Phase mix: 124 late (III/IV) vs 197 early (I/II) (early-phase heavy).
Top condition: Type 2 Diabetes (13 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Brigham and Women's Hospital: open-pipeline peers nationwide
Peers matched on 937 registered trials and 15% open enrollment, not the therapeutic-area sidebar.
Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 937 trials (± recruiting share)
- Columbia University · 958 trials · 18% recruiting
- Hoffmann-La Roche · 909 trials · 8% recruiting
- University of Minnesota · 966 trials · 19% recruiting
- University of California, Los Angeles · 897 trials · 18% recruiting
Sponsors near 15% open enrollment (± trial volume)
- Incyte Corporation · 15% recruiting · 239 trials
- Northwestern University · 15% recruiting · 1,209 trials
- Nationwide Children's Hospital · 15% recruiting · 188 trials
- University of Michigan Rogel Cancer Center · 15% recruiting · 292 trials
Related
What to do with this Brigham and Women's Hospital page
937 registered trials is a research-attention snapshot, not an endorsement of Brigham and Women's Hospital or any single study.
- 145 of Brigham and Women's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Type 2 Diabetes is the condition Brigham and Women's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Type 2 Diabetes trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Brigham and Women's Hospital pipeline card: 937 registered trials from official public datasets.Report a data error.