Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Insomnia: full-pipeline trial registry
62 of 152 indexed Insomnia trials are currently recruiting.
Corpus placement: #74 of 28,707 conditions by registered trial count.
152 US clinical trials · 62 currently recruiting · #74 of 28,707 conditions by registered trial count
Insomnia: 152 US clinical trials tracked, 62 recruiting.
Insomnia is the subject of 152 registered US clinical trials on ClinicalTrials.gov, 62 of them currently open to new participants. 17 are in Phase 3-4 (later-stage) and 21 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 9 of these trials.
Enrollment posture brief
Registry condition insomnia
OPEN 62 | RECR 41% | LATE 17 | EARLY 21 | RANK #74 | SPON 9
Volume-matched condition peers
Nearest open-share peer: Brain Injuries, Traumatic (41% recruiting · 22 trials)
Insomnia lists 62 open slots (41% of 152 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Insomnia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Insomnia is recruiting above its size-band peers.
62 of 152 indexed trials (40.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Insomnia trials is spread across many organizations.
VA Office of Research and Development accounts for 9 of 152 trials (5.9%). 86 distinct sponsors appear on at least one study for this condition label.
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Typical Insomnia enrolment sits around 80 participants.
Median target enrolment is 80 among the 152 trials that report a genuine target (sentinel values excluded). 85 of those (55.9%) plan for fewer than 100 participants.
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Insomnia research is mostly interventional.
147 interventional and 5 observational studies make up this index (96.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
152 total, page 1 of 4
Digital CBT for Insomnia and Depression
University of Rochester
NCT05456607
Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia Symptoms
Brigham and Women's Hospital
NCT07136415
Registry to Collect Information on Pregnancy, Neonatal, and Infant Outcomes in Pregnant Women Exposed to QUVIVIQ®
Idorsia Pharmaceuticals
NCT06498128
Enhancing Digital CBT-I to Improve Adherence and Reduce Disparities
Henry Ford Health System
NCT05182372
Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia
Milton S. Hershey Medical Center
NCT06281756
Sleep to Reduce Incident Depression Effectively in Peripartum
Henry Ford Health System
NCT06430333
Enhancing Hypnotic Medication Discontinuation in Primary Care
National Jewish Health
NCT06435520
Treatments for Insomnia in Veterans With PTSD
VA Office of Research and Development
NCT05194930
CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms
Johns Hopkins University
NCT05663034
A Hybrid Effectiveness Implementation Trial Evaluating Behavioral Treatments for Insomnia for Socioeconomically Disadvantaged Adults in Primary Care
Brigham and Women's Hospital
NCT05759065
Project Women's Insomnia Sleep Health Equity Study (WISHES)
Yale University
NCT06348082
A Study of Suvorexant (MK-4305) for the Treatment of Insomnia Disorder in Participants With Opioid Use Disorder (MK-4305-098)
Merck Sharp & Dohme
NCT06655883
Resilience Enhancement Following Sleep Treatment
University of Virginia
NCT07298941
Move and Snooze: Adding Insomnia Treatment to an Exercise Program to Improve Pain Outcomes in Older Adults With Knee Osteoarthritis
University of Michigan
NCT06580561
Sleep as a Mechanism of Change in Alcohol Use
University of Missouri-Columbia
NCT06286774
The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer
Johns Hopkins University
NCT05780814
Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior
Jeff Bridge
NCT05390918
Targeting Insomnia to Improve Outcomes in Adults With Problematic Cannabis Use
University of Michigan
NCT05814822
Healthy Behaviors for Insomnia Prevention in People With HIV and Ongoing Pain
Washington University School of Medicine
NCT07270406
Multi-center Trial to Improve Nocturia and Sleep in Older Adults
Atlanta VA Medical Center
NCT06110091
mPATH for Low-income Older Adults
Johns Hopkins University
NCT05935241
Behavioral Treatment of Insomnia in Active-Duty Service Members With Traumatic Brain Injury
Noctem
NCT06867666
Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder
University of California, Los Angeles
NCT05516277
Accelerated Treatment for Co-occurring Insomnia, Nightmares, and PTSD
Palo Alto Veterans Institute for Research
NCT07069517
Behavioral Insomnia Treatment in Mild Traumatic Brain Injury
The University of Texas Health Science Center at San Antonio
NCT06551987
Feasibility of Brief Behavioral Therapy for Insomnia (BBTI) in SUD Recovery
Johns Hopkins University
NCT05935735
Sleep Mechanisms Of Regulating Emotions
Stanford University
NCT06373718
Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND)
University of Virginia
NCT05565833
Effectiveness of Transcranial Magnetic Stimulation of the Default Mode Network to Improve Sleep - Clinical Trial
University of Arizona
NCT06631209
Training in Evidence-based Treatments in Psycho-Oncology
Massachusetts General Hospital
NCT05674357
Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse
Yale University
NCT06609369
Treatments in Women Veterans With Insomnia and PTSD
VA Office of Research and Development
NCT05683132
Sleep Treatment Education Program for Cancer Survivors: STEP-Together
Dana-Farber Cancer Institute
NCT06736548
Wearable Transcranial Electrical Stimulation (tES) for Insomnia
Uniformed Services University of the Health Sciences
NCT06100185
NiteCAPP: Web-based Interventions for Insomnia in Rural Dementia Caregivers
University of South Florida
NCT04896775
Effects of Lemborexant on Insomnia and Its Relationship to Mood and Behavior on Opioid Use Disorder Subjects
Virginia Commonwealth University
NCT06981195
Comparing Telehealth-Delivered CBT-I to Web-Based CBT-I to Enhance Sleep, Reduce Fatigue, and Promote Neuroprotection
University of Kansas Medical Center
NCT06434571
The Effect of Sleep Loss on Emotion Regulation
Beth Israel Deaconess Medical Center
NCT05393830
RISE: A Remote Study of Insomnia Treatment in Crohn's Disease
Dartmouth-Hitchcock Medical Center
NCT05956158
Restorative Early Sleep Treatment After the Emergency Department
Henry Ford Health System
NCT07121270
University of Colorado - Restoring Efficient Sleep After TBI
VA Eastern Colorado Health Care System
NCT05683145
Innovating CBT-I for Cancer Survivors: An Optimization Trial
Massachusetts General Hospital
NCT06181643
CF Wellness Program
Johns Hopkins University
NCT07071324
Suvorexant for Treatment of AUD and PTSD
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
NCT06679062
Efficacy of Cognitive Behavioral Therapy for Insomnia to Treat Insomnia Symptoms in Individuals With Multiple Sclerosis
University of Kansas Medical Center
NCT06428006
Adapting CBT-I for Hazardous Alcohol Users
University of Rochester
NCT05973955
Efficacy of Suvorexant in the Treatment of Insomnia in Midlife Women With Pre-Diabetes
Brigham and Women's Hospital
NCT05593653
Pimavanserin for Insomnia in Veterans With PTSD
VA Office of Research and Development
NCT05441280
Noradrenergic Dysregulation, Sleep and Cognition in Older Adults with Insomnia
Northwestern University
NCT06694441
The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers
Rhode Island Hospital
NCT06737055
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 5 |
| Phase 2 | 16 |
| Phase 3 | 5 |
| Phase 4 | 12 |
Top Sponsors
Named interventions
Most-linked intervention names on Insomnia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Insomnia trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Insomnia page
152 registered trials, 62 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 62 Insomnia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Insomnia trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Insomnia condition card totals 152 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.