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ClinicalTrials.gov 46 recruiting now official registry

Chronic Kidney Diseases clinical trials

Every US clinical trial registered for Chronic Kidney Diseases — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

74 US clinical trials · 46 currently recruiting

The research picture

Chronic Kidney Diseases has 74 registered US clinical trials, 46 of them open to new participants right now — about 62% of the total.

46
recruiting participants now
62%
of trials open to enrollment
6
in Phase 3–4 (later-stage)
6
top sponsor: Brigham and Women's Hospital

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 10,000 participants

Real World Evidence Clinical Utility Study of KidneyIntelX

Renalytix AI

NCT04802395

RECRUITING NA 3,000 participants

Home Hospital for Suddenly Ill Adults

Brigham and Women's Hospital

NCT03524222

RECRUITING 1,000 participants

Kidney Precision Medicine Project

University of Washington

NCT04334707

RECRUITING NA 798 participants

Care Transitions App for Patients With Multiple Chronic Conditions

Brigham and Women's Hospital

NCT06051058

RECRUITING Phase 3 685 participants

Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease

Prokidney

NCT05099770

RECRUITING NA 600 participants

SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

VenoStent

NCT06001827

RECRUITING 600 participants

APOL1 Genetic Testing in African Americans

St. Louis University

NCT05656261

RECRUITING 500 participants

American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)

University of New Mexi

NCT04185844

RECRUITING NA 500 participants

Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads

University of South Carolina

NCT05370014

RECRUITING NA 425 participants

A Cardiometabolic Health Program Linked With Clinical-Community Support and Mobile Health Telemonitoring to Reduce Health Disparities

Johns Hopkins University

NCT05321368

RECRUITING NA 388 participants

Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence

University of Tennessee

NCT06374277

RECRUITING NA 330 participants

Kidney Health: Eat Well, Live Well

University of Texas at Austin

NCT05970341

RECRUITING 330 participants

Mixed Methods Study of Health-Related Social Needs in African American Adults With Chronic Kidney Disease and Type 2 Diabetes Mellitus

Medical College of Wisconsin

NCT05692388

RECRUITING NA 326 participants

Chronic Kidney Disease-Education (CKD-EDU)

University of Rochester

NCT06410144

RECRUITING 300 participants

Partners Calciphylaxis Biobank

Massachusetts General Hospital

NCT03032835

RECRUITING 300 participants

BLOOM: Biological Legacy of Origin in Mother-Infant Dyads

University of Miami

NCT02000895

RECRUITING Phase 2 201 participants

Combination of Novel Therapies for CKD Comorbid Depression

Stony Brook University

NCT04422652

RECRUITING NA 175 participants

SPYRAL GEMINI Pilot Study

Medtronic Vascular

NCT06907147

RECRUITING Phase 2 160 participants

Ferric Citrate and Chronic Kidney Disease in Children

University of California, Los Angeles

NCT04741646

RECRUITING Phase 2 156 participants

Sit Less, Interact and Move More (SLIMM) 2 Study

Srinvasan Beddhu

NCT05173714

RECRUITING NA 150 participants

Mindfulness in Chronic Kidney Disease

Emory University

NCT04099992

RECRUITING NA 144 participants

Accelerated Age-related Cognitive Decline: Impact of Exercise on Executive Function and Neuroplasticity

Columbia University

NCT05655325

RECRUITING Early Phase 1 125 participants

Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease

Brigham and Women's Hospital

NCT06190158

RECRUITING NA 120 participants

Interactive Computer-adaptive Chronic Kidney Disease Education Program

University of Chicago

NCT06364358

RECRUITING NA 108 participants

Inspiratory Muscle Strength Training in Chronic Kidney Disease

University of Colorado, Denver

NCT04911491

RECRUITING Phase 2 103 participants

Bone in CKD Alkali Response (BICARb Pilot Trial)

Albert Einstein College of Medicine

NCT05918029

RECRUITING NA 100 participants

Physical Activity in CKD

Children's Hospital of Philadelphia

NCT06624358

RECRUITING Phase 2 80 participants

Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD

University of California, Davis

NCT04984226

RECRUITING 80 participants

A Long-Term Follow-Up Study of Participants Exposed to REACT

Prokidney

NCT05918523

RECRUITING NA 76 participants

A Pilot Study of The CKM JumpStart Tool

University of Washington

NCT05753020

RECRUITING 75 participants

Safety and Tolerability of Vertebral Bone Marrow-derived Mesenchymal Stem Cells (BM-MSC) in Real World Scenarios of Patients With Chronic Kidney Disease (CKD)

Mayo Clinic

NCT06752577

RECRUITING Phase 2 75 participants

Janus Kinase-STAT Inhibition to Reduce APOL1 Associated Kidney Disease

Duke University

NCT05237388

RECRUITING Phase 1 60 participants

Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease

Northwestern University

NCT05719714

RECRUITING Phase 4 60 participants

Effect of Empagliflozin on Podocyte Specific Proteins in African American Veterans With NDKD

Washington D.C. Veterans Affairs Medical Center

NCT06110130

RECRUITING NA 50 participants

Handgrip Exercise Training and CKD

Emory University

NCT07094906

RECRUITING Phase 4 40 participants

Oral Iron in Children With Chronic Kidney Disease

Weill Medical College of Cornell University

NCT03991169

RECRUITING Early Phase 1 40 participants

Feasibility Trial of Sodium-GLucose coTransporter 2 INhibitors in Pediatric Chronic KIDney DiSease

Ann & Robert H Lurie Children's Hospital of Chicago

NCT06430684

RECRUITING 40 participants

Precision Medicine Approaches to Renal Osteodystrophy

Thomas Nickolas

NCT05880914

RECRUITING Phase 2 38 participants

Acute Equol Supplementation and Vascular Function in Women With and Without CKD

University of Colorado, Denver

NCT06128278

RECRUITING NA 30 participants

Enhancing Physical Function in Older Adults With Chronic Kidney Disease

Wake Forest University Health Sciences

NCT06738394

RECRUITING NA 30 participants

Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Chronic Kidney Disease (CKD)

NYU Langone Health

NCT06927024

RECRUITING Early Phase 1 30 participants

Concomitant Renal and Urinary Bladder Allograft Transplantation

Mayo Clinic

NCT04626167

RECRUITING NA 30 participants

Diuretic Tuner Clinical Decision Support

University of Texas Southwestern Medical Center

NCT04759274

RECRUITING Phase 4 28 participants

Pioglitazone to Reduce Sympathetic Overactivity in CKD Patients

The University of Texas at Arlington

NCT03471117

RECRUITING Phase 2 20 participants

Anti-Inflammatory Treatment of Uremic Cardiomyopathy With Colchicine

Brigham and Women's Hospital

NCT04500665

RECRUITING Phase 1 10 participants

Delayed Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-matched Kidney Transplants

University of California, Los Angeles

NCT05525507

ACTIVE NOT RECRUITING 2,000 participants

Prospective Decision Impact Clinical Utility Trial of KidneyIntelX

Renalytix AI

NCT05198284

ACTIVE NOT RECRUITING NA 1,452 participants

Patient Education Video to Reduce OTC NSAIDs

Carilion Clinic

NCT06575205

ACTIVE NOT RECRUITING NA 1,300 participants

SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN

Medtronic Vascular

NCT05198674

ACTIVE NOT RECRUITING 600 participants

BRINK (BRain In Kidney Disease) Memory Study 2.0

Anne Murray

NCT04975464

ACTIVE NOT RECRUITING NA 422 participants

Increasing Live Donor Kidney Transplantation Through Video-based Education and Mobile Communication

State University of New York at Buffalo

NCT05154773

ACTIVE NOT RECRUITING NA 206 participants

APOL1 Genetic Testing Program for Living Donors

Northwestern University

NCT04910867

ACTIVE NOT RECRUITING NA 70 participants

Pregnancy and Contraception Education in Chronic Kidney Disease (PACE-CKD)

University of Michigan

NCT06189807

ACTIVE NOT RECRUITING Phase 1 50 participants

Study of DISC-0974 to Assess the Safety, Tolerability, PK and PD of DISC-0974 in Participants With CKD and Anemia

Disc Medicine

NCT05745883

ACTIVE NOT RECRUITING Phase 4 30 participants

Ferric Citrate in ESRD Pilot Project

Sreedhar Mandayam

NCT03055598

ACTIVE NOT RECRUITING Phase 4 30 participants

Immunogenicity of HPV Vaccine in Transplant Recipients.

Medical College of Wisconsin

NCT05557370

ACTIVE NOT RECRUITING NA 25 participants

Developing Tools for Dialysis Decision Support

VA Palo Alto Health Care System

NCT06597279

ACTIVE NOT RECRUITING Phase 1 16 participants

Immunological Tolerance in Patients With Mismatched Kidney Transplants

University of California, Los Angeles

NCT05806749

ACTIVE NOT RECRUITING NA 13 participants

Evaluation of Increased Fruits and Vegetables Consumption in Chronic Kidney Disease

Nand Wadhwa

NCT05050110

COMPLETED NA 1,168 participants

System Interventions to Achieve Early and Equitable Transplants (STEPS) Study

Wake Forest University Health Sciences

NCT05014256

COMPLETED NA 999 participants

Improving Albuminuria Screening Compliance Using a Smartphone Urinalysis Kit

Geisinger Clinic

NCT03470701

COMPLETED 555 participants

World Trade Center Kidney-Link

Icahn School of Medicine at Mount Sinai

NCT03234530

COMPLETED NA 222 participants

Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions

Duke University

NCT03938324

COMPLETED NA 172 participants

Remote Physician Care for Home Hospital Patients

Brigham and Women's Hospital

NCT04080570

COMPLETED NA 153 participants

Supportive Understanding and Patient-centered Partnership for Optimizing Renal Treatment

University of Pennsylvania

NCT06378476

COMPLETED 78 participants

Sickle Cell Uric Acid (SCUA) - Cohort Repository

Virginia Commonwealth University

NCT04190888

COMPLETED 77 participants

Iron Deficiency and FGF23 Regulation in CKD and HF

Northwestern University

NCT03106298

COMPLETED NA 70 participants

Helping Empower Liver and Kidney Patients

Washington University School of Medicine

NCT03426787

COMPLETED NA 67 participants

Living With CKD: An E-Learning Platform for Adolescents With CKD About the Disease and Its Management

3-C Institute for Social Development

NCT05630729

COMPLETED NA 63 participants

Activity Trackers for Improving BP

University of California, San Francis

NCT03325426

COMPLETED NA 58 participants

Feasibility of Enhanced Dialysis Education (EDU) Intervention for Chronic Kidney Disease (CKD) Patients

University of Rochester

NCT03465449

COMPLETED NA 31 participants

Renal Effects of Melatonin Trial in Chronic Kidney Disease

University of Oklahoma

NCT04336566

COMPLETED NA 20 participants

Pilot to Examine Risk and Feasibility of Remote Management of BP From Childhood Into Early Adulthood

University of California, San Francis

NCT03691701

COMPLETED NA 7 participants

Rural Home Hospital: Proof of Concept

Brigham and Women's Hospital

NCT04531280

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 8
Phase 3 1
Phase 4 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Chronic Kidney Diseases Trial Landscape

ClinicalTrials.gov lists 74 US studies indexed under Chronic Kidney Diseases, and 46 of those are currently open to recruitment — roughly 62% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Chronic Kidney Diseases shows 6 late-stage studies (Phase 3 and Phase 4 combined) alongside 15 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Chronic Kidney Diseases is led by Brigham and Women's Hospital with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 74 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Chronic Kidney Diseases?

PlainTrial tracks 74 US clinical trials for Chronic Kidney Diseases, of which 46 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Chronic Kidney Diseases?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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