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ClinicalTrials.gov 46 recruiting now early-phase tilt

Chronic Kidney Diseases: early-phase trial registry

46 of 74 indexed Chronic Kidney Diseases trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #183 of 28,707 conditions by registered trial count.

74 US clinical trials · 46 currently recruiting · #183 of 28,707 conditions by registered trial count

Chronic Kidney Diseases: 74 US clinical trials tracked, 46 recruiting.

Chronic Kidney Diseases is the subject of 74 registered US clinical trials on ClinicalTrials.gov, 46 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is Brigham and Women's Hospital, running 6 of these trials.

Enrollment posture brief

Registry condition chronic-kidney-diseases

OPEN 46 | RECR 62% | LATE 6 | EARLY 15 | RANK #183 | SPON 6

Nearest open-share peer: Advanced Breast Cancer (62% recruiting · 29 trials)

Chronic Kidney Diseases (thi…62%Anatomic Stage II Breast Can54.1%Chronic Myelomonocytic Leuke40.5%Anemia18.9%HIV Infection12.2%
Open-enrollment share among volume-matched conditions near Chronic Kidney Diseases

Chronic Kidney Diseases lists 46 open slots (62% of 74 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Chronic Kidney Diseases on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Chronic Kidney Diseases is recruiting above its size-band peers.

    46 of 74 indexed trials (62.2%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Chronic Kidney Diseases trials is spread across many organizations.

    Brigham and Women's Hospital accounts for 6 of 74 trials (8.1%). 53 distinct sponsors appear on at least one study for this condition label.

  3. Typical Chronic Kidney Diseases enrolment sits around 108 participants.

    Median target enrolment is 108 among the 74 trials that report a genuine target (sentinel values excluded). 35 of those (47.3%) plan for fewer than 100 participants.

  4. Chronic Kidney Diseases research is mostly interventional.

    59 interventional and 15 observational studies make up this index (79.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 17Phase 28Phase 31Phase 45

Open and recent trials

74 total, page 1 of 2

RECRUITING 10,000 participants

Real World Evidence Clinical Utility Study of KidneyIntelX

Renalytix AI

NCT04802395

RECRUITING NA 3,000 participants

Home Hospital for Suddenly Ill Adults

Brigham and Women's Hospital

NCT03524222

RECRUITING 1,000 participants

Kidney Precision Medicine Project

University of Washington

NCT04334707

RECRUITING NA 798 participants

Care Transitions App for Patients With Multiple Chronic Conditions

Brigham and Women's Hospital

NCT06051058

RECRUITING Phase 3 685 participants

Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease

Prokidney

NCT05099770

RECRUITING NA 600 participants

SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

VenoStent

NCT06001827

RECRUITING 600 participants

APOL1 Genetic Testing in African Americans

St. Louis University

NCT05656261

RECRUITING 500 participants

American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)

University of New Mexi

NCT04185844

RECRUITING NA 500 participants

Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads

University of South Carolina

NCT05370014

RECRUITING NA 425 participants

A Cardiometabolic Health Program Linked With Clinical-Community Support and Mobile Health Telemonitoring to Reduce Health Disparities

Johns Hopkins University

NCT05321368

RECRUITING NA 388 participants

Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence

University of Tennessee

NCT06374277

RECRUITING NA 330 participants

Kidney Health: Eat Well, Live Well

University of Texas at Austin

NCT05970341

RECRUITING 330 participants

Mixed Methods Study of Health-Related Social Needs in African American Adults With Chronic Kidney Disease and Type 2 Diabetes Mellitus

Medical College of Wisconsin

NCT05692388

RECRUITING NA 326 participants

Chronic Kidney Disease-Education (CKD-EDU)

University of Rochester

NCT06410144

RECRUITING 300 participants

Partners Calciphylaxis Biobank

Massachusetts General Hospital

NCT03032835

RECRUITING 300 participants

BLOOM: Biological Legacy of Origin in Mother-Infant Dyads

University of Miami

NCT02000895

RECRUITING Phase 2 201 participants

Combination of Novel Therapies for CKD Comorbid Depression

Stony Brook University

NCT04422652

RECRUITING NA 175 participants

SPYRAL GEMINI Pilot Study

Medtronic Vascular

NCT06907147

RECRUITING Phase 2 160 participants

Ferric Citrate and Chronic Kidney Disease in Children

University of California, Los Angeles

NCT04741646

RECRUITING Phase 2 156 participants

Sit Less, Interact and Move More (SLIMM) 2 Study

Srinvasan Beddhu

NCT05173714

RECRUITING NA 150 participants

Mindfulness in Chronic Kidney Disease

Emory University

NCT04099992

RECRUITING NA 144 participants

Accelerated Age-related Cognitive Decline: Impact of Exercise on Executive Function and Neuroplasticity

Columbia University

NCT05655325

RECRUITING Early Phase 1 125 participants

Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease

Brigham and Women's Hospital

NCT06190158

RECRUITING NA 120 participants

Interactive Computer-adaptive Chronic Kidney Disease Education Program

University of Chicago

NCT06364358

RECRUITING NA 108 participants

Inspiratory Muscle Strength Training in Chronic Kidney Disease

University of Colorado, Denver

NCT04911491

RECRUITING Phase 2 103 participants

Bone in CKD Alkali Response (BICARb Pilot Trial)

Albert Einstein College of Medicine

NCT05918029

RECRUITING NA 100 participants

Physical Activity in CKD

Children's Hospital of Philadelphia

NCT06624358

RECRUITING Phase 2 80 participants

Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD

University of California, Davis

NCT04984226

RECRUITING 80 participants

A Long-Term Follow-Up Study of Participants Exposed to REACT

Prokidney

NCT05918523

RECRUITING NA 76 participants

A Pilot Study of The CKM JumpStart Tool

University of Washington

NCT05753020

RECRUITING 75 participants

Safety and Tolerability of Vertebral Bone Marrow-derived Mesenchymal Stem Cells (BM-MSC) in Real World Scenarios of Patients With Chronic Kidney Disease (CKD)

Mayo Clinic

NCT06752577

RECRUITING Phase 2 75 participants

Janus Kinase-STAT Inhibition to Reduce APOL1 Associated Kidney Disease

Duke University

NCT05237388

RECRUITING Phase 1 60 participants

Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease

Northwestern University

NCT05719714

RECRUITING Phase 4 60 participants

Effect of Empagliflozin on Podocyte Specific Proteins in African American Veterans With NDKD

Washington D.C. Veterans Affairs Medical Center

NCT06110130

RECRUITING NA 50 participants

Handgrip Exercise Training and CKD

Emory University

NCT07094906

RECRUITING Phase 4 40 participants

Oral Iron in Children With Chronic Kidney Disease

Weill Medical College of Cornell University

NCT03991169

RECRUITING Early Phase 1 40 participants

Feasibility Trial of Sodium-GLucose coTransporter 2 INhibitors in Pediatric Chronic KIDney DiSease

Ann & Robert H Lurie Children's Hospital of Chicago

NCT06430684

RECRUITING 40 participants

Precision Medicine Approaches to Renal Osteodystrophy

Thomas Nickolas

NCT05880914

RECRUITING Phase 2 38 participants

Acute Equol Supplementation and Vascular Function in Women With and Without CKD

University of Colorado, Denver

NCT06128278

RECRUITING NA 30 participants

Enhancing Physical Function in Older Adults With Chronic Kidney Disease

Wake Forest University Health Sciences

NCT06738394

RECRUITING NA 30 participants

Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Chronic Kidney Disease (CKD)

NYU Langone Health

NCT06927024

RECRUITING Early Phase 1 30 participants

Concomitant Renal and Urinary Bladder Allograft Transplantation

Mayo Clinic

NCT04626167

RECRUITING NA 30 participants

Diuretic Tuner Clinical Decision Support

University of Texas Southwestern Medical Center

NCT04759274

RECRUITING Phase 4 28 participants

Pioglitazone to Reduce Sympathetic Overactivity in CKD Patients

The University of Texas at Arlington

NCT03471117

RECRUITING Phase 2 20 participants

Anti-Inflammatory Treatment of Uremic Cardiomyopathy With Colchicine

Brigham and Women's Hospital

NCT04500665

RECRUITING Phase 1 10 participants

Delayed Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-matched Kidney Transplants

University of California, Los Angeles

NCT05525507

ACTIVE NOT RECRUITING 2,000 participants

Prospective Decision Impact Clinical Utility Trial of KidneyIntelX

Renalytix AI

NCT05198284

ACTIVE NOT RECRUITING NA 1,452 participants

Patient Education Video to Reduce OTC NSAIDs

Carilion Clinic

NCT06575205

ACTIVE NOT RECRUITING NA 1,300 participants

SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN

Medtronic Vascular

NCT05198674

ACTIVE NOT RECRUITING 600 participants

BRINK (BRain In Kidney Disease) Memory Study 2.0

Anne Murray

NCT04975464

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Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 8
Phase 3 1
Phase 4 5

Named interventions

Most-linked intervention names on Chronic Kidney Diseases records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
7 trials
Placebo Other
3 trials
KidneyIntelX Diagnostic test
2 trials
Sham Training Device
2 trials
Ferric Citrate Drug
2 trials
Empagliflozin 10 MG Drug
2 trials
Mailed Urinalysis Smartphone Kit Other
1 trials
Trauma-Informed Care Training Other
1 trials

US sites by state

Facility locations filed on Chronic Kidney Diseases trials. A trial with sites in several states counts in each.

New York 15 trials
California 13 trials
Texas 9 trials
Massachusetts 9 trials
Pennsylvania 7 trials
North Carolina 7 trials
Florida 6 trials
Missouri 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Chronic Kidney Diseases page

74 registered trials, 46 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Chronic Kidney Diseases condition card totals 74 registered trials; most-linked intervention Placebo; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.