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Chronic Kidney Diseases clinical trials
Every US clinical trial registered for Chronic Kidney Diseases — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
74 US clinical trials · 46 currently recruiting
The research picture
Chronic Kidney Diseases has 74 registered US clinical trials, 46 of them open to new participants right now — about 62% of the total.
- 46
- recruiting participants now
- 62%
- of trials open to enrollment
- 6
- in Phase 3–4 (later-stage)
- 6
- top sponsor: Brigham and Women's Hospital
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Real World Evidence Clinical Utility Study of KidneyIntelX
Renalytix AI
NCT04802395
Home Hospital for Suddenly Ill Adults
Brigham and Women's Hospital
NCT03524222
Kidney Precision Medicine Project
University of Washington
NCT04334707
Care Transitions App for Patients With Multiple Chronic Conditions
Brigham and Women's Hospital
NCT06051058
Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease
Prokidney
NCT05099770
SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study
VenoStent
NCT06001827
APOL1 Genetic Testing in African Americans
St. Louis University
NCT05656261
American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)
University of New Mexi
NCT04185844
Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads
University of South Carolina
NCT05370014
A Cardiometabolic Health Program Linked With Clinical-Community Support and Mobile Health Telemonitoring to Reduce Health Disparities
Johns Hopkins University
NCT05321368
Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
University of Tennessee
NCT06374277
Kidney Health: Eat Well, Live Well
University of Texas at Austin
NCT05970341
Mixed Methods Study of Health-Related Social Needs in African American Adults With Chronic Kidney Disease and Type 2 Diabetes Mellitus
Medical College of Wisconsin
NCT05692388
Chronic Kidney Disease-Education (CKD-EDU)
University of Rochester
NCT06410144
Partners Calciphylaxis Biobank
Massachusetts General Hospital
NCT03032835
BLOOM: Biological Legacy of Origin in Mother-Infant Dyads
University of Miami
NCT02000895
Combination of Novel Therapies for CKD Comorbid Depression
Stony Brook University
NCT04422652
SPYRAL GEMINI Pilot Study
Medtronic Vascular
NCT06907147
Ferric Citrate and Chronic Kidney Disease in Children
University of California, Los Angeles
NCT04741646
Sit Less, Interact and Move More (SLIMM) 2 Study
Srinvasan Beddhu
NCT05173714
Mindfulness in Chronic Kidney Disease
Emory University
NCT04099992
Accelerated Age-related Cognitive Decline: Impact of Exercise on Executive Function and Neuroplasticity
Columbia University
NCT05655325
Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease
Brigham and Women's Hospital
NCT06190158
Interactive Computer-adaptive Chronic Kidney Disease Education Program
University of Chicago
NCT06364358
Inspiratory Muscle Strength Training in Chronic Kidney Disease
University of Colorado, Denver
NCT04911491
Bone in CKD Alkali Response (BICARb Pilot Trial)
Albert Einstein College of Medicine
NCT05918029
Physical Activity in CKD
Children's Hospital of Philadelphia
NCT06624358
Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD
University of California, Davis
NCT04984226
A Long-Term Follow-Up Study of Participants Exposed to REACT
Prokidney
NCT05918523
A Pilot Study of The CKM JumpStart Tool
University of Washington
NCT05753020
Safety and Tolerability of Vertebral Bone Marrow-derived Mesenchymal Stem Cells (BM-MSC) in Real World Scenarios of Patients With Chronic Kidney Disease (CKD)
Mayo Clinic
NCT06752577
Janus Kinase-STAT Inhibition to Reduce APOL1 Associated Kidney Disease
Duke University
NCT05237388
Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease
Northwestern University
NCT05719714
Effect of Empagliflozin on Podocyte Specific Proteins in African American Veterans With NDKD
Washington D.C. Veterans Affairs Medical Center
NCT06110130
Handgrip Exercise Training and CKD
Emory University
NCT07094906
Oral Iron in Children With Chronic Kidney Disease
Weill Medical College of Cornell University
NCT03991169
Feasibility Trial of Sodium-GLucose coTransporter 2 INhibitors in Pediatric Chronic KIDney DiSease
Ann & Robert H Lurie Children's Hospital of Chicago
NCT06430684
Precision Medicine Approaches to Renal Osteodystrophy
Thomas Nickolas
NCT05880914
Acute Equol Supplementation and Vascular Function in Women With and Without CKD
University of Colorado, Denver
NCT06128278
Enhancing Physical Function in Older Adults With Chronic Kidney Disease
Wake Forest University Health Sciences
NCT06738394
Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Chronic Kidney Disease (CKD)
NYU Langone Health
NCT06927024
Concomitant Renal and Urinary Bladder Allograft Transplantation
Mayo Clinic
NCT04626167
Diuretic Tuner Clinical Decision Support
University of Texas Southwestern Medical Center
NCT04759274
Pioglitazone to Reduce Sympathetic Overactivity in CKD Patients
The University of Texas at Arlington
NCT03471117
Anti-Inflammatory Treatment of Uremic Cardiomyopathy With Colchicine
Brigham and Women's Hospital
NCT04500665
Delayed Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-matched Kidney Transplants
University of California, Los Angeles
NCT05525507
Prospective Decision Impact Clinical Utility Trial of KidneyIntelX
Renalytix AI
NCT05198284
Patient Education Video to Reduce OTC NSAIDs
Carilion Clinic
NCT06575205
SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
Medtronic Vascular
NCT05198674
BRINK (BRain In Kidney Disease) Memory Study 2.0
Anne Murray
NCT04975464
Increasing Live Donor Kidney Transplantation Through Video-based Education and Mobile Communication
State University of New York at Buffalo
NCT05154773
APOL1 Genetic Testing Program for Living Donors
Northwestern University
NCT04910867
Pregnancy and Contraception Education in Chronic Kidney Disease (PACE-CKD)
University of Michigan
NCT06189807
Study of DISC-0974 to Assess the Safety, Tolerability, PK and PD of DISC-0974 in Participants With CKD and Anemia
Disc Medicine
NCT05745883
Ferric Citrate in ESRD Pilot Project
Sreedhar Mandayam
NCT03055598
Immunogenicity of HPV Vaccine in Transplant Recipients.
Medical College of Wisconsin
NCT05557370
Developing Tools for Dialysis Decision Support
VA Palo Alto Health Care System
NCT06597279
Immunological Tolerance in Patients With Mismatched Kidney Transplants
University of California, Los Angeles
NCT05806749
Evaluation of Increased Fruits and Vegetables Consumption in Chronic Kidney Disease
Nand Wadhwa
NCT05050110
System Interventions to Achieve Early and Equitable Transplants (STEPS) Study
Wake Forest University Health Sciences
NCT05014256
Improving Albuminuria Screening Compliance Using a Smartphone Urinalysis Kit
Geisinger Clinic
NCT03470701
World Trade Center Kidney-Link
Icahn School of Medicine at Mount Sinai
NCT03234530
Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions
Duke University
NCT03938324
Remote Physician Care for Home Hospital Patients
Brigham and Women's Hospital
NCT04080570
Supportive Understanding and Patient-centered Partnership for Optimizing Renal Treatment
University of Pennsylvania
NCT06378476
Sickle Cell Uric Acid (SCUA) - Cohort Repository
Virginia Commonwealth University
NCT04190888
Iron Deficiency and FGF23 Regulation in CKD and HF
Northwestern University
NCT03106298
Helping Empower Liver and Kidney Patients
Washington University School of Medicine
NCT03426787
Living With CKD: An E-Learning Platform for Adolescents With CKD About the Disease and Its Management
3-C Institute for Social Development
NCT05630729
Activity Trackers for Improving BP
University of California, San Francis
NCT03325426
Feasibility of Enhanced Dialysis Education (EDU) Intervention for Chronic Kidney Disease (CKD) Patients
University of Rochester
NCT03465449
Renal Effects of Melatonin Trial in Chronic Kidney Disease
University of Oklahoma
NCT04336566
Pilot to Examine Risk and Feasibility of Remote Management of BP From Childhood Into Early Adulthood
University of California, San Francis
NCT03691701
Rural Home Hospital: Proof of Concept
Brigham and Women's Hospital
NCT04531280
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 7 |
| Phase 2 | 8 |
| Phase 3 | 1 |
| Phase 4 | 5 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Chronic Kidney Diseases Trial Landscape
ClinicalTrials.gov lists 74 US studies indexed under Chronic Kidney Diseases, and 46 of those are currently open to recruitment — roughly 62% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Chronic Kidney Diseases shows 6 late-stage studies (Phase 3 and Phase 4 combined) alongside 15 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Chronic Kidney Diseases is led by Brigham and Women's Hospital with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 74 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Chronic Kidney Diseases?
PlainTrial tracks 74 US clinical trials for Chronic Kidney Diseases, of which 46 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Chronic Kidney Diseases?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.