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NCT06282146 · ClinicalTrials.gov registry record · Early Phase 1

Testing a Transdiagnostic TMS Treatment Target

A Early Phase 1 study of Depression and Major Depressive Disorder, sponsored by Brigham and Women's Hospital.

Active
Registry status
Early Phase 1
Development phase
10
Enrollment target
1
Study location

NCT06282146 is a Early Phase 1 study of Depression and Major Depressive Disorder that is active but no longer recruiting, run by Brigham and Women's Hospital. The registered enrollment target is 10 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06282146, a Early Phase 1 study of Depression and Major Depressive Disorder, is active but no longer recruiting, sponsored by Brigham and Women's Hospital.

ACTIVE NOT RECRUITING
Registry status
Early Phase 1
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to test a new brain stimulation treatment target for individuals with depression plus at least one additional psychiatric disorder. The main question is to understand the safety profile of a non-invasive form of brain stimulation called accelerated intermittent theta burst stimulation when it is targeting the posterior parietal cortex. Additional questions focus on whether this stimulation improves symptoms of depression and other psychiatric disorders as well as whether this stimulation changes brain function.

Conditions Studied

Depression Major Depressive Disorder PTSD Anxiety Disorders Mood Disorders Mental Disorder OCD Psychiatric Disorder

Interventions

  • PROCEDURE transcranial magnetic stimulation

Study Locations (1)

Massachusetts

  • Brigham and Women's Hospital - Boston

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2024-09-09
Est. Completion 2026-05-01
Phase Early Phase 1

Sponsor

Brigham and Women's Hospital

937 total trials

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What the Registry Record Tells You About NCT06282146

The ClinicalTrials.gov registry entry for NCT06282146 describes a study currently listed as active not recruiting, categorized as Early Phase 1. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 679 other Depression trials with a reported enrollment target (99% lower). The listed sponsor is Brigham and Women's Hospital, which has 937 total studies on file at ClinicalTrials.gov.

The record links to 8 conditions, with Depression appearing as the primary indexed condition, and to 1 intervention - of which transcranial magnetic stimulation is the first listed.

NCT06282146 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT06282146 about?

NCT06282146 is a clinical study titled "Testing a Transdiagnostic TMS Treatment Target". The goal of this clinical trial is to test a new brain stimulation treatment target for individuals with depression plus at least one additional psychiatric disorder. The main question is to understand the safety profile of a non-invasive form of brain stimulation called accelerated intermittent the...

What is the current status of trial NCT06282146?

This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 10 participants. The study started on 2024-09-09. Estimated completion is 2026-05-01.

What conditions does trial NCT06282146 study?

This clinical trial studies the following conditions: Depression, Major Depressive Disorder, PTSD, Anxiety Disorders, Mood Disorders.

What interventions are being tested in trial NCT06282146?

The interventions under investigation include: transcranial magnetic stimulation (PROCEDURE).

Who is sponsoring clinical trial NCT06282146?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06282146 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.