Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05232669 · ClinicalTrials.gov registry record · NA
COcoa Supplement and Multivitamin Outcomes Study: Effects on Falls and Physical Performance
A NA study of Fall and Fracture, sponsored by Brigham and Women's Hospital.
- Active
- Registry status
- NA
- Development phase
- 21,442
- Enrollment target
- 1
- Study location
NCT05232669: Active NA study of Fall and Fracture, sponsored by Brigham and Women's Hospital.
NCT05232669 is a NA study of Fall and Fracture that is active but no longer recruiting, run by Brigham and Women's Hospital. The registered enrollment target is 21,442 participants, above the 179-participant average among 19 other Fall trials with a reported enrollment target (11879% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05232669, a NA study of Fall and Fracture, is active but no longer recruiting, sponsored by Brigham and Women's Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 21,442 participants
- Enrollment target
- 1
- Study location
Study Summary
The COcoa Supplement and Multivitamin Outcomes Study (COSMOS; NCT02422745) is a randomized clinical trial of cocoa extract supplement (containing a total of 500 mg/d flavanols, including 80 mg. (-)-epicatechins), and a standard multivitamin supplement to reduce the risk of cardiovascular disease and cancer among men aged 60 years and older and women aged 65 years and older. This ancillary study is being conducted among participants in COSMOS and will examine whether the cocoa extract supplement or the multivitamin supplement improve musculoskeletal health and prevent falls and declining physical performance in the increasing number of older adults in the U.S. with potential for clinical and public health benefits.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Multivitamin
- DIETARY_SUPPLEMENT Cocoa extract
- DIETARY_SUPPLEMENT Cocoa extract placebo
- DIETARY_SUPPLEMENT Multivitamin placebo
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21,442 participants |
| Start Date | 2021-05-15 |
| Est. Completion | 2026-02 |
| Phase | NA |
What the registry record for NCT05232669 still lists
NCT05232669 is an interventional study that assigns participants to a tested intervention. Its 21,442 participants enrollment target places it among the larger protocols in the corpus, above the 179-participant average among 19 other Fall trials with a reported enrollment target (11879% higher).
The record links to 3 conditions, with Fall appearing as the primary indexed condition, and to 4 interventions - of which Multivitamin is the first listed.
NCT05232669 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05232669 about?
NCT05232669 is a clinical study titled "COcoa Supplement and Multivitamin Outcomes Study: Effects on Falls and Physical Performance". The COcoa Supplement and Multivitamin Outcomes Study (COSMOS; NCT02422745) is a randomized clinical trial of cocoa extract supplement (containing a total of 500 mg/d flavanols, including 80 mg. (-)-epicatechins), and a standard multivitamin supplement to reduce the risk of cardiovascular disease and...
What is the current status of trial NCT05232669?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 21,442 participants. The study started on 2021-05-15. Estimated completion is 2026-02.
What conditions does trial NCT05232669 study?
This clinical trial studies the following conditions: Fall, Fracture, Physical Performance.
What interventions are being tested in trial NCT05232669?
The interventions under investigation include: Multivitamin (DIETARY_SUPPLEMENT), Cocoa extract (DIETARY_SUPPLEMENT), Cocoa extract placebo (DIETARY_SUPPLEMENT), Multivitamin placebo (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT05232669?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05232669 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Fall
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05232669's enrollment target sits among peer trials
21,442 1st of 19 higher than 19 of 19 other Fall trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Fall trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
The Geriatric Emergency Department Pharmacologic Harm Prevention Project
RECRUITING · NA
-
Optimizing a Technology-based Body and Mind Intervention
RECRUITING · NA
-
Comparison of Smartphone and Community-Based Delivery of the Otago Exercise Program for Fall Risk in Older Adults
RECRUITING · NA
-
Integrated Tele-Behavioral Activation and Fall Prevention for Low-income Homebound Seniors With Depression
RECRUITING · NA
-
Real-life Dual-Task Training
RECRUITING · NA
-
Exercise Program for Deaf Seniors to Increase Their Balance and Fitness
ACTIVE NOT RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT06047041 · 21,350 participants · NA
Implementation Supports for Improving Identification and Delivery of School-based Mental Health Supports for Middle Schools Students
- NCT07213531 · 21,000 participants
Enhanced Valves Interventions and Safe AI Generated End Results
- NCT05832307 · 22,000 participants · NA
The INFLUENTIAL Trial- Evaluation of National Inpatient Influenza Vaccination Program
- NCT05488080 · 22,032 participants · NA
PAINED: Project Addressing INequities in the Emergency Department
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI