University of Michigan Rogel Cancer Center
Trial Pipeline
Virus-Based Gene Therapy (AdV-HSV1-TK and AdV-Flt3L) in Combination With Valacyclovir for the Treatment of Pediatric and Young Adult Patients With Resectable, Recurrent Primary Malignant Brain Tumors
NCT06914479
Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP)
NCT06641310
A Virtually Delivered Diet Intervention (LASO-3) for the Improvement of Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors Post-treatment
NCT07365007
Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer
NCT06616155
Leuprolide and Goserelin for Ovarian Function Suppression in Pre- or Peri-menopausal Women With Breast Cancer, OFS Trial
NCT07158021
A Self-Monitoring Platform for Tracking Medication Safety and Concerns in Cancer Patients
NCT07291414
Ivonescimab Before Surgery for the Treatment of Resectable Stage II-IV Head and Neck Cancer
NCT07094685
Phase II Study of Resistant Potato Starch Plus Deferasirox to Improve Outcomes in Patients Undergoing Allogeneic Stem Cell Transplantation
NCT06784336
Navigation Interventions to Improve Cascade Genetic Testing Among Relatives of Patients With Hereditary Cancer Syndromes
NCT06927947
An Investigational Scan ([68Ga] Ga-FAPI-04 PET/CT) for the Imaging of Patients With High-Grade Neuroendocrine Cancer
NCT07132645
Inulin Gel in Combination With Ipilimumab and Nivolumab for the Treatment of Metastatic or Locally Advanced Kidney Cell Cancer, ICON Trial
NCT06866262
Study of Neoadjuvant Enfortumab Vedotin and Pembrolizumab in Cisplatin-eligible Upper Tract Urothelial Cancer
NCT06356155
Personalized Neck Radiation Therapy Directed by Sentinel Lymph Node Biopsy for the Treatment of Oral Cavity Squamous Cell Carcinoma, PRECEDENT Trial
NCT07121595
Solution-Focused Brief Therapy for Support of Psychological Distress in Adolescent and Young Adult Cancer Survivors
NCT06941324
Pilot Investigation of Dual Energy CT Imaging on an Online Adaptive Radiation Therapy System
NCT07219134
Pembrolizumab for the Treatment of Locally Advanced and/or Recurrent Orbital or Periocular Cutaneous Squamous Cell Carcinoma
NCT06580054
SPECT/CT Imaging for Dosimetry in 177Lu-PSMA-617 (Pluvicto) Therapy
NCT07096999
CIPN Decision Aid for the Improvement of Chemotherapy Decision Making in Patients With Breast Cancer
NCT06915168
Active Surveillance for the Treatment of Low-Risk Basal Cell Carcinoma in Elderly Patients
NCT06539468
Gilteritinib for the Treatment of ALK NSCLC
NCT06225427
Breast Cancer Resiliency Through Exercise Program (B-REP)
NCT06100263
Multicenter Trial of ESK981 in Patients With Select Solid Tumors
NCT05988918
Living Well With Lymphoma
NCT06047626
Study of Ribociclib Administered Concurrently With Postoperative Radiation Therapy in Patients With High-Risk, HR+/HER2- Breast Cancer
NCT05996107
A Pilot Study of Liver Protection Using Prednisone for Patients Receiving Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma
NCT05901519
Pembrolizumab and Mogamulizumab in Advanced-stage, Relapsed/Refractory Cutaneous T-cell Lymphomas
NCT05956041
Interstitial Assessment of Architectural Heterogeneity in Prostate Cancer Using a Fine Needle Photoacoustic Probe
NCT05965180
Prehabilitation Program to Improve Cardiac Reserve in High-Risk Patients Undergoing Hematopoietic Stem Cell Transplantation
NCT05945121
Parametric Response Mapping (PRM) for the Detection of Chronic Lung Injury in Hematopoietic Cell Transplant Recipients
NCT05866302
A Phase II Study for p16+ Oropharyngeal Cancer PerSonalized De-escalation Treatment at University of MIchigan (CuSToMIze)
NCT05894083
Localized Leiomyosarcoma Biomarker Protocol
NCT04925089
Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative Neoplasms
NCT04858256
Metastatic Leiomyosarcoma Biomarker Protocol
NCT05653388
Pharmacokinetic Study of Skeletal Muscle Area-based Paclitaxel Infusion in Patients With Cancer
NCT05183126
Post-prostatectomy Radiation Therapy--Moderate Versus Ultra-hypofractionated (Also Known as Stereotactic Body Radiation Therapy [SBRT])
NCT05038332
Genomics in Michigan to AdJust Outcomes in Prostate canceR (G-MAJOR) for Men With Newly Diagnosed Favorable Risk Prostate Cancer
NCT04396808
Combined Y-90 Selective Internal Radiation Therapy (Y-90 SIRT) and Stereotactic Body Radiation Therapy (SBRT) in Hepatic Malignancy.
NCT04518748
Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas
NCT00843375
Cyclophosphamide and Sirolimus for the Treatment of Metastatic, RAI-refractory, Differentiated Thyroid Cancer
NCT03099356
Dietary Manipulation of the Microbiome-metabolomic Axis for Mitigating GVHD in Allo HCT Patients
NCT02763033
Quantitative MRI for Myelofibrosis
NCT01973881
Feasibility of Virtual, Tailored, Music-Based Relaxation for Anxiety in Adolescent and Young Adult Cancer Survivors
NCT05911269
Trial of Individualized Adaptive RT in HPV-related High Risk Oropharynx Cancer
NCT06234748
Focal Radiation With Pulsed Systemic Therapy of Abiraterone, Androgen Deprivation Therapy (ADT), Lynparza Towards Castration Sensitive Oligometastatic Prostate Cancer (FAALCON)
NCT04748042
Pembrolizumab and Lenvatinib in Advanced/Metastatic Neuroendocrine Prostate Cancer
NCT04848337
A Multi-Center Trial of Androgen Suppression With Abiraterone Acetate, Leuprolide, PARP Inhibition and Stereotactic Body Radiotherapy in Prostate Cancer
NCT04194554
Multiparametric MR-Guided High Dose Adaptive Radiotherapy With Concurrent Temozolomide in Patients With Newly Diagnosed Glioblastoma
NCT04574856
Phase 2 Study With Minimal Residual Disease (MRD) Driven Adaptive Strategy in Treatment for Newly Diagnosed Multiple Myeloma (MM) With Upfront Daratumumab-based Therapy
NCT04140162
Mycophenolate Mofetil Combined With Radiation Therapy in Glioblastoma
NCT04477200
Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation
NCT03842696
Targeting Resistant Prostate Cancer With ATR and PARP Inhibition (TRAP Trial)
NCT03787680
APG-115 in Salivary Gland Cancer Trial
NCT03781986
The IDEA Study (Individualized Decisions for Endocrine Therapy Alone)
NCT02400190
Feasibility of Expressive Writing for Body Image Distress and Anxiety Among Adolescent and Young Adult Cancer Survivors
NCT06046014
Acupressure for Aromatase Inhibitor-Associated Musculoskeletal Symptoms in Patients With Breast Cancer
NCT06228768
The Genetic Information and Family Testing (GIFT) Study
NCT05552664
Avoiding Low-value Treatments in Older Women With Early-stage Breast Cancer: Piloting a Patient Decision Aid
NCT05140252
Developing a Psychosexual Educational Partners Program: PEPP A Feasibility Study
NCT05070299
Improving Quality of Life Using Patient Reported Outcomes Measures Post-operative Via Text Messaging
NCT04852471
Sleep Coach: A Mobile App to Address Insomnia Symptoms Among Cancer Survivors
NCT04827459
Trabectedin in Combination With Olaparib in Advanced Unresectable or Metastatic Sarcoma
NCT04076579
Acupressure for Fatigue in Ovarian Cancer Survivors
NCT03763838
Nivolumab and the Antagonistic CSF-1R Monoclonal Antibody Cabiralizumab (BMS-986227) in Patients With Relapsed/Refractory Peripheral T Cell Lymphoma
NCT03927105
Individualized Adaptive De-escalated Radiotherapy for HPV-related Oropharynx Cancer
NCT03416153
Neoadjuvant Stereotactic Body Radiotherapy Prior to Radical Prostatectomy for High Risk Prostate Cancer
NCT02946008
Functional Imaging in Lung SBRT
NCT03121300
Genomics in Michigan Impacting Observation or Radiation
NCT02783950
A Study of High-Dose Chemoradiation Using Biologically-Based Target Volume Definition in Patients With Glioblastoma
NCT02805179
Clinical Outcomes, Nutritional Status, Exercise and Psychosocial Factors in Pediatric Hematopoietic Cell Transplant
NCT02734797
A Pilot Study of MPDL3280A and HIGRT in Metastatic NSCLC
NCT02463994
Early Imaging Biomarkers in NSCLC
NCT03121287
A Novel Health Information Technology System (BMT Roadmap) for Pediatric BMT Patients and Caregivers
NCT02409121
Phase 2 Multi-center Study of Anti-PD-1 During Lymphopenic State After HDT/ASCT for Multiple Myeloma
NCT02331368
Vorinostat Plus Tacrolimus & Methotrexate to Prevent Graft vs Host Disease Following Unrelated Stem Cell Transplant
NCT01790568
Phase 1/2 Study of Carfilzomib for the Prevention of Relapse and GVHD in Allo-HCT for Hematologic Malignancies
NCT02145403
A Pilot Study of Alpha-1-Antitrypsin (AAT) in Steroid Refractory Acute Graft vs Host Disease
NCT01700036
A Trial of Cabozantinib (XL184) and Gemcitabine in Advanced Pancreatic Cancer
NCT01663272
Evaluation of Metformin, Targeting Cancer Stem Cells for Prevention of Relapse in Gynecologic Patients
NCT01579812
A Trial of Gemcitabine, Infusional 5-Fluorouracil and Cisplatin for Advanced Pancreatic and Biliary Cancers
NCT01661114
A Study of Individualized Stereotactic Body Radiation Therapy (SBRT) for Intrahepatic Cancer
NCT01522937
Loss of Grip Strength, BMI, and Adjuvant Endocrine Therapy Breast Cancer
NCT01896050
Pilot Study to Evaluate the Effect of Aromatase Inhibitor Therapy on Pain Threshold in Breast Cancer Patients
NCT01814397
A Study Using Cone Beam CT for Head and Neck Cancer
NCT01661062
Sunitinib Maintenance Therapy After Induction Platinum-Based Chemotherapy in Patients With ES-SCLC
NCT00616109
Early Assessment of Treatment Response Using Functional Diffusion Mapping
NCT02064283
Imaging Biomarker for Early Detection of Treatment Efficacy During Breast Cancer Neoadjuvant Chemotherapy
NCT02679586
A Pilot Study of Bone Mineral Density in Postmenopausal Women After Treatment for Breast Cancer
NCT00399321
Cross-Sectional Study of Oral Health in Patients After Parotid-Sparing Radiation Therapy for Head and Neck Cancer
NCT01663246
Tissue Procurement Protocol for Patients Undergoing Neoadjuvant Systemic Therapy for Breast Cancer
NCT00161265
MRI Study of Changes in Blood-Brain/Tumor-Barrier Permeability in Patients With Brain Metastases During and After Radiotherapy
NCT02031237
Study of Combination Therapy With VELCADE, Doxil, and Dexamethasone (VDd) in Multiple Myeloma
NCT00135187
Evaluation of Tumor Factors in Breast Cancer Treated With Docetaxel and Capecitabine
NCT00156312
Study of Low-Intensity Conditioning for Allogeneic Stem Cell Transplant
NCT00143845
Gleevec Maintenance Therapy After Induction Irinotecan and Cisplatin in Patients With C-Kit Positive Extensive SCLC
NCT00156286
Tetrathiomolybdate in Hormone Refractory Prostate Cancer
NCT00150995
Azacitidine Plus Amifostine in Treating Patients With Myelodysplastic Syndrome
NCT00005598
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 44 |
| Phase 2 | 90 |
| Phase 4 | 1 |
Therapeutic Areas
What the Pipeline for University of Michigan Rogel Cancer Center Shows
According to the ClinicalTrials.gov registry, University of Michigan Rogel Cancer Center is linked to 261 US clinical trials across every stage of research activity. Of those, 206 studies are currently recruiting — about 79% of the sponsor's indexed portfolio — and 43 are already marked complete, representing roughly 16% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for University of Michigan Rogel Cancer Center reports 1 late-stage studies (Phase 3 and Phase 4 combined) and 134 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for University of Michigan Rogel Cancer Center is Breast Cancer with 12 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.