University of Michigan Rogel Cancer Center

261 total trials 206 currently recruiting 43 completed

Trial Pipeline

RECRUITING Phase 1

Virus-Based Gene Therapy (AdV-HSV1-TK and AdV-Flt3L) in Combination With Valacyclovir for the Treatment of Pediatric and Young Adult Patients With Resectable, Recurrent Primary Malignant Brain Tumors

NCT06914479

RECRUITING NA

Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP)

NCT06641310

RECRUITING NA

A Virtually Delivered Diet Intervention (LASO-3) for the Improvement of Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors Post-treatment

NCT07365007

RECRUITING Phase 1

Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer

NCT06616155

RECRUITING Phase 2

Leuprolide and Goserelin for Ovarian Function Suppression in Pre- or Peri-menopausal Women With Breast Cancer, OFS Trial

NCT07158021

RECRUITING NA

A Self-Monitoring Platform for Tracking Medication Safety and Concerns in Cancer Patients

NCT07291414

RECRUITING Phase 2

Ivonescimab Before Surgery for the Treatment of Resectable Stage II-IV Head and Neck Cancer

NCT07094685

RECRUITING Phase 2

Phase II Study of Resistant Potato Starch Plus Deferasirox to Improve Outcomes in Patients Undergoing Allogeneic Stem Cell Transplantation

NCT06784336

RECRUITING NA

Navigation Interventions to Improve Cascade Genetic Testing Among Relatives of Patients With Hereditary Cancer Syndromes

NCT06927947

RECRUITING Early Phase 1

An Investigational Scan ([68Ga] Ga-FAPI-04 PET/CT) for the Imaging of Patients With High-Grade Neuroendocrine Cancer

NCT07132645

RECRUITING Phase 1

Inulin Gel in Combination With Ipilimumab and Nivolumab for the Treatment of Metastatic or Locally Advanced Kidney Cell Cancer, ICON Trial

NCT06866262

RECRUITING Phase 2

Study of Neoadjuvant Enfortumab Vedotin and Pembrolizumab in Cisplatin-eligible Upper Tract Urothelial Cancer

NCT06356155

RECRUITING Phase 2

Personalized Neck Radiation Therapy Directed by Sentinel Lymph Node Biopsy for the Treatment of Oral Cavity Squamous Cell Carcinoma, PRECEDENT Trial

NCT07121595

RECRUITING NA

Solution-Focused Brief Therapy for Support of Psychological Distress in Adolescent and Young Adult Cancer Survivors

NCT06941324

RECRUITING

Pilot Investigation of Dual Energy CT Imaging on an Online Adaptive Radiation Therapy System

NCT07219134

RECRUITING Phase 2

Pembrolizumab for the Treatment of Locally Advanced and/or Recurrent Orbital or Periocular Cutaneous Squamous Cell Carcinoma

NCT06580054

RECRUITING

SPECT/CT Imaging for Dosimetry in 177Lu-PSMA-617 (Pluvicto) Therapy

NCT07096999

RECRUITING NA

CIPN Decision Aid for the Improvement of Chemotherapy Decision Making in Patients With Breast Cancer

NCT06915168

RECRUITING NA

Active Surveillance for the Treatment of Low-Risk Basal Cell Carcinoma in Elderly Patients

NCT06539468

RECRUITING Phase 1

Gilteritinib for the Treatment of ALK NSCLC

NCT06225427

RECRUITING NA

Breast Cancer Resiliency Through Exercise Program (B-REP)

NCT06100263

RECRUITING Phase 2

Multicenter Trial of ESK981 in Patients With Select Solid Tumors

NCT05988918

RECRUITING NA

Living Well With Lymphoma

NCT06047626

RECRUITING Phase 1

Study of Ribociclib Administered Concurrently With Postoperative Radiation Therapy in Patients With High-Risk, HR+/HER2- Breast Cancer

NCT05996107

RECRUITING Phase 2

A Pilot Study of Liver Protection Using Prednisone for Patients Receiving Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma

NCT05901519

RECRUITING Phase 2

Pembrolizumab and Mogamulizumab in Advanced-stage, Relapsed/Refractory Cutaneous T-cell Lymphomas

NCT05956041

RECRUITING

Interstitial Assessment of Architectural Heterogeneity in Prostate Cancer Using a Fine Needle Photoacoustic Probe

NCT05965180

RECRUITING NA

Prehabilitation Program to Improve Cardiac Reserve in High-Risk Patients Undergoing Hematopoietic Stem Cell Transplantation

NCT05945121

RECRUITING

Parametric Response Mapping (PRM) for the Detection of Chronic Lung Injury in Hematopoietic Cell Transplant Recipients

NCT05866302

RECRUITING Phase 2

A Phase II Study for p16+ Oropharyngeal Cancer PerSonalized De-escalation Treatment at University of MIchigan (CuSToMIze)

NCT05894083

RECRUITING

Localized Leiomyosarcoma Biomarker Protocol

NCT04925089

RECRUITING Phase 2

Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative Neoplasms

NCT04858256

RECRUITING

Metastatic Leiomyosarcoma Biomarker Protocol

NCT05653388

RECRUITING Phase 4

Pharmacokinetic Study of Skeletal Muscle Area-based Paclitaxel Infusion in Patients With Cancer

NCT05183126

RECRUITING Phase 2

Post-prostatectomy Radiation Therapy--Moderate Versus Ultra-hypofractionated (Also Known as Stereotactic Body Radiation Therapy [SBRT])

NCT05038332

RECRUITING NA

Genomics in Michigan to AdJust Outcomes in Prostate canceR (G-MAJOR) for Men With Newly Diagnosed Favorable Risk Prostate Cancer

NCT04396808

RECRUITING Phase 1

Combined Y-90 Selective Internal Radiation Therapy (Y-90 SIRT) and Stereotactic Body Radiation Therapy (SBRT) in Hepatic Malignancy.

NCT04518748

RECRUITING

Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas

NCT00843375

RECRUITING Phase 2

Cyclophosphamide and Sirolimus for the Treatment of Metastatic, RAI-refractory, Differentiated Thyroid Cancer

NCT03099356

RECRUITING Phase 2

Dietary Manipulation of the Microbiome-metabolomic Axis for Mitigating GVHD in Allo HCT Patients

NCT02763033

RECRUITING

Quantitative MRI for Myelofibrosis

NCT01973881

ACTIVE NOT RECRUITING NA

Feasibility of Virtual, Tailored, Music-Based Relaxation for Anxiety in Adolescent and Young Adult Cancer Survivors

NCT05911269

ACTIVE NOT RECRUITING Phase 2

Trial of Individualized Adaptive RT in HPV-related High Risk Oropharynx Cancer

NCT06234748

ACTIVE NOT RECRUITING Phase 2

Focal Radiation With Pulsed Systemic Therapy of Abiraterone, Androgen Deprivation Therapy (ADT), Lynparza Towards Castration Sensitive Oligometastatic Prostate Cancer (FAALCON)

NCT04748042

ACTIVE NOT RECRUITING Phase 2

Pembrolizumab and Lenvatinib in Advanced/Metastatic Neuroendocrine Prostate Cancer

NCT04848337

ACTIVE NOT RECRUITING Phase 1

A Multi-Center Trial of Androgen Suppression With Abiraterone Acetate, Leuprolide, PARP Inhibition and Stereotactic Body Radiotherapy in Prostate Cancer

NCT04194554

ACTIVE NOT RECRUITING Phase 2

Multiparametric MR-Guided High Dose Adaptive Radiotherapy With Concurrent Temozolomide in Patients With Newly Diagnosed Glioblastoma

NCT04574856

ACTIVE NOT RECRUITING Phase 2

Phase 2 Study With Minimal Residual Disease (MRD) Driven Adaptive Strategy in Treatment for Newly Diagnosed Multiple Myeloma (MM) With Upfront Daratumumab-based Therapy

NCT04140162

ACTIVE NOT RECRUITING Phase 1

Mycophenolate Mofetil Combined With Radiation Therapy in Glioblastoma

NCT04477200

ACTIVE NOT RECRUITING Phase 1

Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation

NCT03842696

ACTIVE NOT RECRUITING Phase 2

Targeting Resistant Prostate Cancer With ATR and PARP Inhibition (TRAP Trial)

NCT03787680

ACTIVE NOT RECRUITING Phase 1

APG-115 in Salivary Gland Cancer Trial

NCT03781986

ACTIVE NOT RECRUITING NA

The IDEA Study (Individualized Decisions for Endocrine Therapy Alone)

NCT02400190

COMPLETED NA

Feasibility of Expressive Writing for Body Image Distress and Anxiety Among Adolescent and Young Adult Cancer Survivors

NCT06046014

COMPLETED NA

Acupressure for Aromatase Inhibitor-Associated Musculoskeletal Symptoms in Patients With Breast Cancer

NCT06228768

COMPLETED NA

The Genetic Information and Family Testing (GIFT) Study

NCT05552664

COMPLETED NA

Avoiding Low-value Treatments in Older Women With Early-stage Breast Cancer: Piloting a Patient Decision Aid

NCT05140252

COMPLETED NA

Developing a Psychosexual Educational Partners Program: PEPP A Feasibility Study

NCT05070299

COMPLETED NA

Improving Quality of Life Using Patient Reported Outcomes Measures Post-operative Via Text Messaging

NCT04852471

COMPLETED NA

Sleep Coach: A Mobile App to Address Insomnia Symptoms Among Cancer Survivors

NCT04827459

COMPLETED Phase 2

Trabectedin in Combination With Olaparib in Advanced Unresectable or Metastatic Sarcoma

NCT04076579

COMPLETED NA

Acupressure for Fatigue in Ovarian Cancer Survivors

NCT03763838

COMPLETED Phase 2

Nivolumab and the Antagonistic CSF-1R Monoclonal Antibody Cabiralizumab (BMS-986227) in Patients With Relapsed/Refractory Peripheral T Cell Lymphoma

NCT03927105

COMPLETED Phase 2

Individualized Adaptive De-escalated Radiotherapy for HPV-related Oropharynx Cancer

NCT03416153

COMPLETED Phase 1

Neoadjuvant Stereotactic Body Radiotherapy Prior to Radical Prostatectomy for High Risk Prostate Cancer

NCT02946008

COMPLETED

Functional Imaging in Lung SBRT

NCT03121300

COMPLETED NA

Genomics in Michigan Impacting Observation or Radiation

NCT02783950

COMPLETED Phase 2

A Study of High-Dose Chemoradiation Using Biologically-Based Target Volume Definition in Patients With Glioblastoma

NCT02805179

COMPLETED

Clinical Outcomes, Nutritional Status, Exercise and Psychosocial Factors in Pediatric Hematopoietic Cell Transplant

NCT02734797

COMPLETED Early Phase 1

A Pilot Study of MPDL3280A and HIGRT in Metastatic NSCLC

NCT02463994

COMPLETED

Early Imaging Biomarkers in NSCLC

NCT03121287

COMPLETED NA

A Novel Health Information Technology System (BMT Roadmap) for Pediatric BMT Patients and Caregivers

NCT02409121

COMPLETED Phase 2

Phase 2 Multi-center Study of Anti-PD-1 During Lymphopenic State After HDT/ASCT for Multiple Myeloma

NCT02331368

COMPLETED Phase 2

Vorinostat Plus Tacrolimus & Methotrexate to Prevent Graft vs Host Disease Following Unrelated Stem Cell Transplant

NCT01790568

COMPLETED Phase 1

Phase 1/2 Study of Carfilzomib for the Prevention of Relapse and GVHD in Allo-HCT for Hematologic Malignancies

NCT02145403

COMPLETED Phase 2

A Pilot Study of Alpha-1-Antitrypsin (AAT) in Steroid Refractory Acute Graft vs Host Disease

NCT01700036

COMPLETED Phase 1

A Trial of Cabozantinib (XL184) and Gemcitabine in Advanced Pancreatic Cancer

NCT01663272

COMPLETED Phase 2

Evaluation of Metformin, Targeting Cancer Stem Cells for Prevention of Relapse in Gynecologic Patients

NCT01579812

COMPLETED Phase 2

A Trial of Gemcitabine, Infusional 5-Fluorouracil and Cisplatin for Advanced Pancreatic and Biliary Cancers

NCT01661114

COMPLETED Phase 2

A Study of Individualized Stereotactic Body Radiation Therapy (SBRT) for Intrahepatic Cancer

NCT01522937

COMPLETED

Loss of Grip Strength, BMI, and Adjuvant Endocrine Therapy Breast Cancer

NCT01896050

COMPLETED

Pilot Study to Evaluate the Effect of Aromatase Inhibitor Therapy on Pain Threshold in Breast Cancer Patients

NCT01814397

COMPLETED NA

A Study Using Cone Beam CT for Head and Neck Cancer

NCT01661062

COMPLETED Phase 2

Sunitinib Maintenance Therapy After Induction Platinum-Based Chemotherapy in Patients With ES-SCLC

NCT00616109

COMPLETED NA

Early Assessment of Treatment Response Using Functional Diffusion Mapping

NCT02064283

COMPLETED Early Phase 1

Imaging Biomarker for Early Detection of Treatment Efficacy During Breast Cancer Neoadjuvant Chemotherapy

NCT02679586

COMPLETED

A Pilot Study of Bone Mineral Density in Postmenopausal Women After Treatment for Breast Cancer

NCT00399321

COMPLETED NA

Cross-Sectional Study of Oral Health in Patients After Parotid-Sparing Radiation Therapy for Head and Neck Cancer

NCT01663246

COMPLETED

Tissue Procurement Protocol for Patients Undergoing Neoadjuvant Systemic Therapy for Breast Cancer

NCT00161265

COMPLETED

MRI Study of Changes in Blood-Brain/Tumor-Barrier Permeability in Patients With Brain Metastases During and After Radiotherapy

NCT02031237

COMPLETED NA

Study of Combination Therapy With VELCADE, Doxil, and Dexamethasone (VDd) in Multiple Myeloma

NCT00135187

COMPLETED NA

Evaluation of Tumor Factors in Breast Cancer Treated With Docetaxel and Capecitabine

NCT00156312

COMPLETED Phase 2

Study of Low-Intensity Conditioning for Allogeneic Stem Cell Transplant

NCT00143845

COMPLETED Phase 2

Gleevec Maintenance Therapy After Induction Irinotecan and Cisplatin in Patients With C-Kit Positive Extensive SCLC

NCT00156286

COMPLETED Phase 2

Tetrathiomolybdate in Hormone Refractory Prostate Cancer

NCT00150995

COMPLETED Phase 2

Azacitidine Plus Amifostine in Treating Patients With Myelodysplastic Syndrome

NCT00005598

What the Pipeline for University of Michigan Rogel Cancer Center Shows

According to the ClinicalTrials.gov registry, University of Michigan Rogel Cancer Center is linked to 261 US clinical trials across every stage of research activity. Of those, 206 studies are currently recruiting — about 79% of the sponsor's indexed portfolio — and 43 are already marked complete, representing roughly 16% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for University of Michigan Rogel Cancer Center reports 1 late-stage studies (Phase 3 and Phase 4 combined) and 134 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for University of Michigan Rogel Cancer Center is Breast Cancer with 12 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial