Brigham and Women's Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Brigham and Women's Hospital sits in the top decile of US sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count).

937 total trials 145 currently recruiting 608 completed early-phase tilt top decile by trial count

Brigham and Women's Hospital: 937 sponsored US clinical trials, 145 recruiting.

Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Type 2 Diabetes, with 13 trials.

Top-decile sponsor footprint

Brigham and Women's Hospital ranks in the top decile of sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 64/100

608 of 677 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

937 total, page 2 of 19

RECRUITING NA

Safety and Feasibility of Tele-supervised Home-based Transcranial Direct Current Stimulation in Parkinson's Disease

NCT06804668

RECRUITING Phase 2

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

NCT06376734

RECRUITING NA

Embolization Treatment of Chronic Refractory Shoulder Tendinopathy

NCT06095050

RECRUITING NA

Leveraging Social Networks to Improve Sleep and Mindfulness Among Older Adults in Residential Housing Facilities

NCT06989619

RECRUITING NA

Positive Psychology Intervention for Hematopoietic Stem Cell Transplantation Survivors

NCT06328127

RECRUITING NA

Can Food Timing Reduce Your Diabetes Risk?

NCT05862818

RECRUITING NA

Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans

NCT06105164

RECRUITING NA

Eating to Adjust the Timing System

NCT05800990

RECRUITING Phase 1

Elranatamab in Patients With Relapsed or Refractory AL Amyloidosis

NCT06569147

RECRUITING NA

Effect of Physical Activity Pattern on Cardiometabolic Health

NCT05838508

RECRUITING NA

Care Transitions App for Patients With Multiple Chronic Conditions

NCT06051058

RECRUITING Phase 2

LIFT: Life Improvement Trial

NCT06366724

RECRUITING

The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study

NCT07315997

RECRUITING NA

AI Detection of Incidental Coronary Artery Calcium to Enhance Cardiovascular Disease Prevention

NCT06235112

RECRUITING NA

Maximizing Lymph Node Dissection on Fresh and Fixed Lung Cancer Resection Specimens

NCT06252129

RECRUITING NA

Exercise Training in Transthyretin Cardiac Amyloidosis

NCT05797857

RECRUITING

Understanding the Acute Pain Phenotype in Patients Undergoing Surgery

NCT06466941

RECRUITING

Novel Treatments in Improving Renal Outcomes in Light Chain Cast Nephropathy

NCT06483139

RECRUITING NA

Experiment 2: One Target in Many Situations

NCT06934148

RECRUITING NA

Mixed Vs Blocked Search: Four Unique Tasks

NCT06933693

RECRUITING NA

Experiment 3: Mixed vs Blocked; Dashboard Paradigm

NCT06934213

RECRUITING Early Phase 1

Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease

NCT06190158

RECRUITING NA

Study on Allopregnanolone and Depression in Women Across the Menopause Transition

NCT06238700

RECRUITING

Ergonomics in the Cardiac Catheterization Laboratory

NCT06506968

RECRUITING Phase 2

Preventing Injured Knees From osteoArthritis: Severity Outcomes

NCT06096259

RECRUITING NA

A Hybrid Effectiveness Implementation Trial Evaluating Behavioral Treatments for Insomnia for Socioeconomically Disadvantaged Adults in Primary Care

NCT05759065

RECRUITING Phase 4

Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan

NCT06099093

RECRUITING NA

Digital Health Navigation for Latino Patients With Type II Diabetes

NCT06283992

RECRUITING NA

Reversible Effect of Falling Ventilatory Drive in Drive-dependent OSA

NCT06091098

RECRUITING

Manual Versus AI-Assisted Clinical Trial Screening Using Large-Language Models

NCT06588452

RECRUITING Phase 1

Pilot Study for Detection of PSMA-Low CRPC-NE Tumors With Fluciclovine PET/CT

NCT06062745

RECRUITING Phase 1

Acetazolamide as a Means to Mitigate Falling Ventilatory Drive and Drive-dependent OSA

NCT06091085

RECRUITING Phase 1

Trazodone on OSA Endotypes

NCT06286189

RECRUITING NA

Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU

NCT06538376

RECRUITING Phase 2

Detoxification of the Liver In PSC (Dolphin)

NCT05835505

RECRUITING Phase 4

ED90 of Bupivacaine After Lidocaine Test Dose with DPE and EPL

NCT06146842

RECRUITING NA

Pilot Testing a Novel Remotely Delivered Intensive Outpatient Program for Individuals With OUD

NCT05817825

RECRUITING Early Phase 1

Drug Screening Using Novel IMD in Salivary and Head and Neck Cancers

NCT05553782

RECRUITING

Role of Caveolin 1 (CAV-1) Deficiency in Response to Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Treatment

NCT06069622

RECRUITING Phase 2

Down Syndrome Obstructive Sleep Apnea

NCT06043440

RECRUITING NA

Impact of Intensive Computerized Cognitive Training

NCT06130735

RECRUITING NA

MCT for the Harvard/UCSF ROBIN Center

NCT06000787

RECRUITING NA

Cerebellar TMS and Satiety in Prader-Willi Syndrome

NCT05938543

RECRUITING Phase 4

Ultrasound Therapy In Cardiac Amyloidosis

NCT04667494

RECRUITING Phase 4

Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension

NCT05593055

RECRUITING NA

Trial of Variable Dialysate Bicarbonate

NCT05814146

RECRUITING NA

MRI Guided Prostate Biopsy

NCT06302595

RECRUITING Phase 1

Rescue Pharmacotherapy for OSA

NCT05293600

RECRUITING NA

Toward Understanding Drivers of Patient Engagement With Digital Mental Health Interventions - Part II

NCT05555875

RECRUITING Phase 2

NAD Augmentation in Diabetes Kidney Disease

NCT05759468

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Phase Distribution

PhaseTrial count
Phase 1 90
Phase 2 107
Phase 3 47
Phase 4 77

What is open in the Brigham and Women's Hospital pipeline

145 recruiting of 937 indexed (15% open); 608 completed (65%).

Phase mix: 124 late (III/IV) vs 197 early (I/II) (early-phase heavy).

Top condition: Type 2 Diabetes (13 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Brigham and Women's Hospital: open-pipeline peers nationwide

Peers matched on 937 registered trials and 15% open enrollment, not the therapeutic-area sidebar.

Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 5%10%15%20% Total trials Recruiting share Brigham and Women's HospitalColumbia UniversityHoffmann-La RocheUniversity of MinnesotaUniversity of California, Los AngelesIncyte CorporationNorthwestern UniversityNationwide Children's HospitalUniversity of Michigan Rogel Cancer Center
Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 937 trials (± recruiting share)

Sponsors near 15% open enrollment (± trial volume)

What to do with this Brigham and Women's Hospital page

937 registered trials is a research-attention snapshot, not an endorsement of Brigham and Women's Hospital or any single study.

  • 145 of Brigham and Women's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Type 2 Diabetes is the condition Brigham and Women's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Type 2 Diabetes trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Brigham and Women's Hospital pipeline card: 937 registered trials from official public datasets.Report a data error.