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NCT04667494 · ClinicalTrials.gov registry record · Phase 4
Ultrasound Therapy In Cardiac Amyloidosis
A Phase 4 study of Amyloidosis Cardiac, sponsored by Brigham and Women's Hospital.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 70
- Enrollment target
- 1
- Study location
NCT04667494: Recruiting Phase 4 study of Amyloidosis Cardiac, sponsored by Brigham and Women's Hospital.
NCT04667494 is a Phase 4 study of Amyloidosis Cardiac that is actively recruiting participants, run by Brigham and Women's Hospital. The registered enrollment target is 70 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04667494, a Phase 4 study of Amyloidosis Cardiac, is actively recruiting participants, sponsored by Brigham and Women's Hospital.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a prospective pilot clinical study of subjects with cardiac amyloidosis and control subjects without amyloidosis where we plan to evaluate changes in myocardial blood flow, systolic and diastolic function before and after sonotherapy.
Primary Outcome
N-13 ammonia or Rubidium-82 PET based measure of myocardial blood flow in ml/gm/min
Conditions Studied
Interventions
- COMBINATION_PRODUCT Sonotherapy
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2023-08-31 |
| Est. Completion | 2027-04-30 |
| Phase | Phase 4 |
What NCT04667494 shows while recruiting
NCT04667494 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (86% lower).
The record links to 1 condition, with Amyloidosis Cardiac appearing as the primary indexed condition, and to 1 intervention - of which Sonotherapy is the first listed.
NCT04667494 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04667494 about?
NCT04667494 is a clinical study titled "Ultrasound Therapy In Cardiac Amyloidosis". This is a prospective pilot clinical study of subjects with cardiac amyloidosis and control subjects without amyloidosis where we plan to evaluate changes in myocardial blood flow, systolic and diastolic function before and after sonotherapy.
What is the current status of trial NCT04667494?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 70 participants. The study started on 2023-08-31. Estimated completion is 2027-04-30.
What conditions does trial NCT04667494 study?
This clinical trial studies the following conditions: Amyloidosis Cardiac.
What interventions are being tested in trial NCT04667494?
The interventions under investigation include: Sonotherapy (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT04667494?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04667494 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Amyloidosis Cardiac
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04667494's enrollment target sits among peer trials
70 1043rd of 2000 higher than 932 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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