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NCT05797857 · ClinicalTrials.gov registry record · NA
Exercise Training in Transthyretin Cardiac Amyloidosis
A NA study of Transthyretin Cardiac Amyloidosis and Amyloid Cardiomyopathy, sponsored by Brigham and Women's Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT05797857: Recruiting NA study of Transthyretin Cardiac Amyloidosis and Amyloid Cardiomyopathy, sponsored by Brigham and Women's Hospital.
NCT05797857 is a NA study of Transthyretin Cardiac Amyloidosis and Amyloid Cardiomyopathy that is actively recruiting participants, run by Brigham and Women's Hospital. The registered enrollment target is 40 participants, below the 626-participant average among 4 other Transthyretin Cardiac Amyloidosis trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05797857, a NA study of Transthyretin Cardiac Amyloidosis and Amyloid Cardiomyopathy, is actively recruiting participants, sponsored by Brigham and Women's Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
Transthyretin cardiac amyloidosis causes debilitating heart failure in older adults. The proposed research will develop a personalized exercise training program to improve functional capacity in patients on optimal treatment for transthyretin cardiac amyloidosis. This is a vital next step to improve functional capacity and quality of life of people suffering from transthyretin cardiac amyloidosis.
Primary Outcome
CPET performed at baseline and 12-weeks, following the exercise intervention will be used to measure aerobic capacity, peak VO2. The change in peak VO2 from baseline to 12 weeks is the primary outcome measure. An increase of \> 1.0 ml/kg/min is considered a clinically meaningful increase
Conditions Studied
Interventions
- OTHER Exercise Training
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2024-07-10 |
| Est. Completion | 2030-06-30 |
| Phase | NA |
What NCT05797857 shows while recruiting
NCT05797857 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 626-participant average among 4 other Transthyretin Cardiac Amyloidosis trials with a reported enrollment target (94% lower).
The record links to 2 conditions, with Transthyretin Cardiac Amyloidosis appearing as the primary indexed condition, and to 1 intervention - of which Exercise Training is the first listed.
NCT05797857 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05797857 about?
NCT05797857 is a clinical study titled "Exercise Training in Transthyretin Cardiac Amyloidosis". Transthyretin cardiac amyloidosis causes debilitating heart failure in older adults. The proposed research will develop a personalized exercise training program to improve functional capacity in patients on optimal treatment for transthyretin cardiac amyloidosis. This is a vital next step to improve...
What is the current status of trial NCT05797857?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2024-07-10. Estimated completion is 2030-06-30.
What conditions does trial NCT05797857 study?
This clinical trial studies the following conditions: Transthyretin Cardiac Amyloidosis, Amyloid Cardiomyopathy.
What interventions are being tested in trial NCT05797857?
The interventions under investigation include: Exercise Training (OTHER).
Who is sponsoring clinical trial NCT05797857?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05797857 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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