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NCT06190158 · ClinicalTrials.gov registry record · Early Phase 1
Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease
A Early Phase 1 study of Type 2 Diabetes and Chronic Kidney Diseases, sponsored by Brigham and Women's Hospital.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 125
- Enrollment target
- 1
- Study location
NCT06190158: Recruiting Early Phase 1 study of Type 2 Diabetes and Chronic Kidney Diseases, sponsored by Brigham and Women's Hospital.
NCT06190158 is a Early Phase 1 study of Type 2 Diabetes and Chronic Kidney Diseases that is actively recruiting participants, run by Brigham and Women's Hospital. The registered enrollment target is 125 participants, below the 3,923-participant average among 327 other Type 2 Diabetes trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06190158, a Early Phase 1 study of Type 2 Diabetes and Chronic Kidney Diseases, is actively recruiting participants, sponsored by Brigham and Women's Hospital.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 125 participants
- Enrollment target
- 1
- Study location
Study Summary
The aim of this protocol is to assess the presence and severity of primary aldosteronism pathophysiology in patients with type 2 diabetes who have, or are at-risk for developing, chronic kidney disease.
Primary Outcome
The plasma aldosterone concentration following saline suppression testing will serve as a metric quantifying the degree of renin-independent aldosterone production (PA pathophysiology)
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Oral sodium suppression test
- DIAGNOSTIC_TEST Saline suppression test
- DIAGNOSTIC_TEST Captopril suppression test
- DIAGNOSTIC_TEST Dexamethasone suppression test
- DIAGNOSTIC_TEST Cosyntropin stimulation test
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 125 participants |
| Start Date | 2024-05-15 |
| Est. Completion | 2029-07-31 |
| Phase | Early Phase 1 |
What NCT06190158 shows while recruiting
NCT06190158 is an interventional study that assigns participants to a tested intervention. The registered 125 participants enrollment target is mid-sized for trials with a published cap, below the 3,923-participant average among 327 other Type 2 Diabetes trials with a reported enrollment target (97% lower).
The record links to 2 conditions, with Type 2 Diabetes appearing as the primary indexed condition, and to 5 interventions - of which Oral sodium suppression test is the first listed.
NCT06190158 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06190158 about?
NCT06190158 is a clinical study titled "Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease". The aim of this protocol is to assess the presence and severity of primary aldosteronism pathophysiology in patients with type 2 diabetes who have, or are at-risk for developing, chronic kidney disease.
What is the current status of trial NCT06190158?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 125 participants. The study started on 2024-05-15. Estimated completion is 2029-07-31.
What conditions does trial NCT06190158 study?
This clinical trial studies the following conditions: Type 2 Diabetes, Chronic Kidney Diseases.
What interventions are being tested in trial NCT06190158?
The interventions under investigation include: Oral sodium suppression test (DIAGNOSTIC_TEST), Saline suppression test (DIAGNOSTIC_TEST), Captopril suppression test (DIAGNOSTIC_TEST), Dexamethasone suppression test (DIAGNOSTIC_TEST), Cosyntropin stimulation test (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT06190158?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06190158 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Type 2 Diabetes
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06190158's enrollment target sits among peer trials
125 130th of 327 higher than 197 of 327 other Type 2 Diabetes trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Type 2 Diabetes trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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