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NCT06105164 · ClinicalTrials.gov registry record · NA
Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans
A NA study of Obesity and Appetitive Behavior, sponsored by Brigham and Women's Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 150
- Enrollment target
- 2
- Study locations
NCT06105164: Recruiting NA study of Obesity and Appetitive Behavior, sponsored by Brigham and Women's Hospital.
NCT06105164 is a NA study of Obesity and Appetitive Behavior that is actively recruiting participants, run by Brigham and Women's Hospital. The registered enrollment target is 150 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (82% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06105164, a NA study of Obesity and Appetitive Behavior, is actively recruiting participants, sponsored by Brigham and Women's Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 150 participants
- Enrollment target
- 2
- Study locations
Study Summary
This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study satiety in healthy individuals. TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the brain. The magnetic field is produced by a coil that is held next to the scalp. In this study, the investigators will be stimulating the brain to learn more about the role of the cerebellum in satiety.
Primary Outcome
Change in functional activation of the cerebellum will be assessed before (pre-TMS) and after (post-rTMS) rTMS stimulation, measured separately at the fed visit and at the fasted visit.
Conditions Studied
Interventions
- DEVICE Repetitive Transcranial Magnetic Stimulation (rTMS)
- DEVICE Sham repetitive Transcranial Magnetic Stimulation (rTMS)
Study Locations (2)
Massachusetts
- McLean Hospital - Belmont
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2024-12-05 |
| Est. Completion | 2029-08 |
| Phase | NA |
What NCT06105164 shows while recruiting
NCT06105164 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (82% lower).
The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which Repetitive Transcranial Magnetic Stimulation (rTMS) is the first listed.
NCT06105164 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06105164 about?
NCT06105164 is a clinical study titled "Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans". This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study satiety in healthy individuals. TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the brain. The magnetic field is produced by a coil that is held next to th...
What is the current status of trial NCT06105164?
This trial is currently recruiting. It is a NA study. The enrollment target is 150 participants. The study started on 2024-12-05. Estimated completion is 2029-08.
What conditions does trial NCT06105164 study?
This clinical trial studies the following conditions: Obesity, Appetitive Behavior.
What interventions are being tested in trial NCT06105164?
The interventions under investigation include: Repetitive Transcranial Magnetic Stimulation (rTMS) (DEVICE), Sham repetitive Transcranial Magnetic Stimulation (rTMS) (DEVICE).
Who is sponsoring clinical trial NCT06105164?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06105164 being conducted?
This trial has 2 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06105164's enrollment target sits among peer trials
150 370th of 1053 higher than 668 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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