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NCT05759468 · ClinicalTrials.gov registry record · Phase 2

NAD Augmentation in Diabetes Kidney Disease

A Phase 2 study of Diabetic Kidney Disease and Type2diabetes, sponsored by Brigham and Women's Hospital.

Recruiting
Registry status
Phase 2
Development phase
140
Enrollment target
1
Study location

NCT05759468 is a Phase 2 study of Diabetic Kidney Disease and Type2diabetes that is actively recruiting participants, run by Brigham and Women's Hospital. The registered enrollment target is 140 participants, below the 5,184-participant average among 23 other Diabetic Kidney Disease trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05759468, a Phase 2 study of Diabetic Kidney Disease and Type2diabetes, is actively recruiting participants, sponsored by Brigham and Women's Hospital.

RECRUITING
Registry status
Phase 2
Development phase
140 participants
Enrollment target
1
Study location

Study Summary

A phase 2a trial randomized, double-blind, placebo-controlled, parallel group trial to determine whether NMN administration improves DKD, as indicated by a significantly greater reduction in UACR compared with placebo administration. Eligible participants will be randomized to receive either 1000 mg NMN or placebo twice daily.

Interventions

  • DRUG Placebo
  • DRUG Investigational Product - MIB 626

Study Locations (1)

Massachusetts

  • Brigham and Women's Hospital - Boston

Trial Details

FieldValue
Enrollment Target 140 participants
Start Date 2023-04-13
Est. Completion 2027-03-31
Phase Phase 2

Sponsor

Brigham and Women's Hospital

937 total trials

What the Registry Record Tells You About NCT05759468

The ClinicalTrials.gov registry entry for NCT05759468 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 140 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 5,184-participant average among 23 other Diabetic Kidney Disease trials with a reported enrollment target (97% lower). The listed sponsor is Brigham and Women's Hospital, which has 937 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Diabetic Kidney Disease appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT05759468 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT05759468 about?

NCT05759468 is a clinical study titled "NAD Augmentation in Diabetes Kidney Disease". A phase 2a trial randomized, double-blind, placebo-controlled, parallel group trial to determine whether NMN administration improves DKD, as indicated by a significantly greater reduction in UACR compared with placebo administration. Eligible participants will be randomized to receive either 1000 mg...

What is the current status of trial NCT05759468?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 140 participants. The study started on 2023-04-13. Estimated completion is 2027-03-31.

What conditions does trial NCT05759468 study?

This clinical trial studies the following conditions: Diabetic Kidney Disease, Type2diabetes.

What interventions are being tested in trial NCT05759468?

The interventions under investigation include: Placebo (DRUG), Investigational Product - MIB 626 (DRUG).

Who is sponsoring clinical trial NCT05759468?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05759468 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.