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NCT06466941 · ClinicalTrials.gov registry record

Understanding the Acute Pain Phenotype in Patients Undergoing Surgery

A clinical trial of Opioid Use and Acute Pain, sponsored by Brigham and Women's Hospital.

Recruiting
Registry status
1,000
Enrollment target
1
Study location

NCT06466941: Recruiting study of Opioid Use and Acute Pain, sponsored by Brigham and Women's Hospital.

NCT06466941 is a study of Opioid Use and Acute Pain that is actively recruiting participants, run by Brigham and Women's Hospital. The registered enrollment target is 1,000 participants, below the 148,251-participant average among 105 other Opioid Use trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06466941, a study of Opioid Use and Acute Pain, is actively recruiting participants, sponsored by Brigham and Women's Hospital.

RECRUITING
Registry status
1,000 participants
Enrollment target
1
Study location

Study Summary

The goal of this observational study is to learn about how regional anesthesia (numbing medication) affects pain in patients with different psychosocial phenotypes such as different levels of concern about pain, sleep issues, and anxiety, who are having surgery. The main questions are: 1. Do psychosocial factors such as concerns about pain, sleep, anxiety affect the effectiveness of regional anesthesia? 2. Do psychosocial factors and regional anesthesia affect the amount of opioids used after surgery? 3. Do psychosocial factors and regional anesthesia affect development of chronic postsurgical pain?

Primary Outcome

Maximum pain score (numerical pain rating score 0-10) over the first 24 hours after surgery

Conditions Studied

Opioid Use Acute Pain Chronic Post Operative Pain

Interventions

  • PROCEDURE regional anesthesia
  • PROCEDURE no regional anesthesia
  • OTHER acute pain consultation
  • OTHER no acute pain consultation

Study Locations (1)

Massachusetts

  • Brigham and Women's Hospital - Boston

Trial Details

FieldValue
Enrollment Target 1,000 participants
Start Date 2024-07-03
Est. Completion 2027-07-01
Brigham and Women's Hospital

937 total trials

What NCT06466941 shows while recruiting

NCT06466941 is an observational study that tracks outcomes without assigning an intervention. Its 1,000 participants enrollment target places it among the larger protocols in the corpus, below the 148,251-participant average among 105 other Opioid Use trials with a reported enrollment target (99% lower).

The record links to 3 conditions, with Opioid Use appearing as the primary indexed condition, and to 4 interventions - of which regional anesthesia is the first listed.

NCT06466941 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT06466941 about?

NCT06466941 is a clinical study titled "Understanding the Acute Pain Phenotype in Patients Undergoing Surgery". The goal of this observational study is to learn about how regional anesthesia (numbing medication) affects pain in patients with different psychosocial phenotypes such as different levels of concern about pain, sleep issues, and anxiety, who are having surgery. The main questions are: 1. Do psych...

What is the current status of trial NCT06466941?

This trial is currently recruiting. The enrollment target is 1,000 participants. The study started on 2024-07-03. Estimated completion is 2027-07-01.

What conditions does trial NCT06466941 study?

This clinical trial studies the following conditions: Opioid Use, Acute Pain, Chronic Post Operative Pain.

What interventions are being tested in trial NCT06466941?

The interventions under investigation include: regional anesthesia (PROCEDURE), no regional anesthesia (PROCEDURE), acute pain consultation (OTHER), no acute pain consultation (OTHER).

Who is sponsoring clinical trial NCT06466941?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06466941 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Opioid Use

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06466941's enrollment target sits among peer trials

1,000 10th of 105 higher than 96 of 105 other Opioid Use trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Opioid Use trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT06466941

Source: ClinicalTrials.gov NCT06466941, the US trial registry maintained by the National Library of Medicine. NCT06466941 (large enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.