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NCT06854458 · ClinicalTrials.gov registry record · NA

The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study

A NA study of Ischemic Heart Disease (IHD) and Cardiac Magnetic Resonance Imaging, sponsored by Brigham and Women's Hospital.

Recruiting
Registry status
NA
Development phase
1,000
Enrollment target
7
Study locations

NCT06854458 is a NA study of Ischemic Heart Disease (IHD) and Cardiac Magnetic Resonance Imaging that is actively recruiting participants, run by Brigham and Women's Hospital. The registered enrollment target is 1,000 participants. The trial reports 7 study locations across 6 states.

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The verdict

NCT06854458, a NA study of Ischemic Heart Disease (IHD) and Cardiac Magnetic Resonance Imaging, is actively recruiting participants, sponsored by Brigham and Women's Hospital.

RECRUITING
Registry status
NA
Development phase
1,000 participants
Enrollment target
7
Study locations

Study Summary

This research aims to investigate whether symptoms of chest pain or shortness of breath among the study population are arising due to a heart problem, particularly any reduction of blood flow to the heart muscle from blockages in the coronary blood vessels or inflammation of the heart using cardiac magnetic resonance imaging that measures the amount of blood flow during a stress state meant to simulate vigorous exercise. At present, doctors use standard magnetic resonance imaging pictures of blood flow patterns to treat heart disease. The investigators want to study if detailed blood flow measurements, in addition to the standard blood flow pattern, could diagnose heart disease more accurately and allow more doctors to understand the severity of heart disease. Early research has demonstrated that detailed blood flow measurements may be more accurate in diagnosing heart disease in some patients, but doctors need more information to know how to use these measurements.

Interventions

  • DIAGNOSTIC_TEST Blood draw for the laboratory assessment
  • DIAGNOSTIC_TEST Quantitative Myocardial Blood Flow Evaluation
  • DIAGNOSTIC_TEST Qualitative Myocardial Blood Flow Evaluation
  • DRUG Gadavist
  • DRUG Vasodilator

Study Locations (7)

Massachusetts

  • Brigham and Women's Hospital - Boston
  • Beth Israel Deaconess Medical Center - Boston

California

  • University of California San Francisco - San Francisco

North Carolina

  • Atrium Health - Sanger Heart & Vascular Institute - Charlotte

Tennessee

  • Vanderbilt University Medical Center - Nashville

Texas

  • Houston Methodist Hospital - Houston

Virginia

  • Virginia Commonwealth University - Richmond

Trial Details

FieldValue
Enrollment Target 1,000 participants
Start Date 2025-06-27
Est. Completion 2029-03
Phase NA

Sponsor

Brigham and Women's Hospital

937 total trials

What the Registry Record Tells You About NCT06854458

The ClinicalTrials.gov registry entry for NCT06854458 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 1,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Brigham and Women's Hospital, which has 937 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Ischemic Heart Disease (IHD) appearing as the primary indexed condition, and to 5 interventions - of which Blood draw for the laboratory assessment is the first listed.

NCT06854458 reports 7 study locations spanning 6 distinct geographic areas - top geographies include Massachusetts, California, North Carolina.

Frequently Asked Questions

What is clinical trial NCT06854458 about?

NCT06854458 is a clinical study titled "The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study". This research aims to investigate whether symptoms of chest pain or shortness of breath among the study population are arising due to a heart problem, particularly any reduction of blood flow to the heart muscle from blockages in the coronary blood vessels or inflammation of the heart using cardiac ...

What is the current status of trial NCT06854458?

This trial is currently recruiting. It is a NA study. The enrollment target is 1,000 participants. The study started on 2025-06-27. Estimated completion is 2029-03.

What conditions does trial NCT06854458 study?

This clinical trial studies the following conditions: Ischemic Heart Disease (IHD), Cardiac Magnetic Resonance Imaging, Myocardial Blood Flow.

What interventions are being tested in trial NCT06854458?

The interventions under investigation include: Blood draw for the laboratory assessment (DIAGNOSTIC_TEST), Quantitative Myocardial Blood Flow Evaluation (DIAGNOSTIC_TEST), Qualitative Myocardial Blood Flow Evaluation (DIAGNOSTIC_TEST), Gadavist (DRUG), Vasodilator (DRUG).

Who is sponsoring clinical trial NCT06854458?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06854458 being conducted?

This trial has 7 study locations across California, Massachusetts, North Carolina, Tennessee, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

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