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NCT06536296 · ClinicalTrials.gov registry record · NA

The Impact of Music Medicine on Preterm Brain Development and Behavior

A NA study of Stress and Infant Development, sponsored by Brigham and Women's Hospital.

Recruiting
Registry status
NA
Development phase
243
Enrollment target
2
Study locations

NCT06536296: Recruiting NA study of Stress and Infant Development, sponsored by Brigham and Women's Hospital.

NCT06536296 is a NA study of Stress and Infant Development that is actively recruiting participants, run by Brigham and Women's Hospital. The registered enrollment target is 243 participants, below the 785-participant average among 152 other Stress trials with a reported enrollment target (69% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06536296, a NA study of Stress and Infant Development, is actively recruiting participants, sponsored by Brigham and Women's Hospital.

RECRUITING
Registry status
NA
Development phase
243 participants
Enrollment target
2
Study locations

Study Summary

The investigators are conducting a two-site randomized control trial with the aim of defining the impact of music (M) without or with parent voice (MPV) on very preterm infants' acute and cumulative stress, intranetwork connectivity on term brain MRI, and language and other neurodevelopmental outcomes at two years corrected age. This is based on the hypothesis that infants in MPV arm are expected to experience the greatest benefit compared with infants receiving standard care.

Primary Outcome

Study patients Language performance measured on the Bayley-4 at 2 years corrected age

Interventions

  • OTHER Standard Care
  • OTHER Music
  • OTHER Music and parent voice

Study Locations (2)

Connecticut

  • Yale New Haven Hospital - New Haven

Massachusetts

  • Brigham and Women's Hospital - Boston

Trial Details

FieldValue
Enrollment Target 243 participants
Start Date 2025-05-19
Est. Completion 2031-03-01
Phase NA
Brigham and Women's Hospital

937 total trials

What NCT06536296 shows while recruiting

NCT06536296 is an interventional study that assigns participants to a tested intervention. The registered 243 participants enrollment target is mid-sized for trials with a published cap, below the 785-participant average among 152 other Stress trials with a reported enrollment target (69% lower).

The record links to 4 conditions, with Stress appearing as the primary indexed condition, and to 3 interventions - of which Standard Care is the first listed.

NCT06536296 reports a single indexed study location in Connecticut, Massachusetts.

Frequently Asked Questions

What is clinical trial NCT06536296 about?

NCT06536296 is a clinical study titled "The Impact of Music Medicine on Preterm Brain Development and Behavior". The investigators are conducting a two-site randomized control trial with the aim of defining the impact of music (M) without or with parent voice (MPV) on very preterm infants' acute and cumulative stress, intranetwork connectivity on term brain MRI, and language and other neurodevelopmental outcom...

What is the current status of trial NCT06536296?

This trial is currently recruiting. It is a NA study. The enrollment target is 243 participants. The study started on 2025-05-19. Estimated completion is 2031-03-01.

What conditions does trial NCT06536296 study?

This clinical trial studies the following conditions: Stress, Infant Development, Prematurity, Language Development.

What interventions are being tested in trial NCT06536296?

The interventions under investigation include: Standard Care (OTHER), Music (OTHER), Music and parent voice (OTHER).

Who is sponsoring clinical trial NCT06536296?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06536296 being conducted?

This trial has 2 study locations across Connecticut, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Stress

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06536296's enrollment target sits among peer trials

243 25th of 152 higher than 128 of 152 other Stress trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Stress trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06536296, the US trial registry maintained by the National Library of Medicine. NCT06536296 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.