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NCT07023523 · ClinicalTrials.gov registry record · NA
Self-regulation of Real-time fMRI Brain Activity in Chronic Pain
A NA study of Fibromyalgia, sponsored by Brigham and Women's Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 36
- Enrollment target
- 1
- Study location
NCT07023523: Recruiting NA study of Fibromyalgia, sponsored by Brigham and Women's Hospital.
NCT07023523 is a NA study of Fibromyalgia that is actively recruiting participants, run by Brigham and Women's Hospital. The registered enrollment target is 36 participants, below the 179-participant average among 76 other Fibromyalgia trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07023523, a NA study of Fibromyalgia, is actively recruiting participants, sponsored by Brigham and Women's Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 36 participants
- Enrollment target
- 1
- Study location
Study Summary
This study aims to explore the usefulness of self-regulation of brain activity in patients with fibromyalgia. Patients will use real-time functional magnetic resonance imaging (fMRI) neurofeedback to observe and regulate their own brain activity while applying mental strategies to reduce fibromyalgia pain. The study consists of 2 magnetic resonance imaging (MRI) visits that involve brain neuroimaging for fMRI neurofeedback tasks, as well as 8 weekly intervention sessions with a pain psychologist. Patients will be randomized to either Cognitive Behavioral Therapy (CBT) or Fibromyalgia Education groups.
Primary Outcome
Changes in brain activity in pain-associated regions such as vPCC (ventral posterior cingulate cortex)/RSC (retrosplenial cortex), quantified as z-scores, during the self-regulation period of the MRI scan.
Conditions Studied
Interventions
- BEHAVIORAL Cognitive Behavioral Therapy
- BEHAVIORAL Disease Education
Study Locations (1)
Massachusetts
- Athinoula A. Martinos Center for Biomedical Imaging - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2025-10-31 |
| Est. Completion | 2026-07 |
| Phase | NA |
What NCT07023523 shows while recruiting
NCT07023523 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 179-participant average among 76 other Fibromyalgia trials with a reported enrollment target (80% lower).
The record links to 1 condition, with Fibromyalgia appearing as the primary indexed condition, and to 2 interventions - of which Cognitive Behavioral Therapy is the first listed.
NCT07023523 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT07023523 about?
NCT07023523 is a clinical study titled "Self-regulation of Real-time fMRI Brain Activity in Chronic Pain". This study aims to explore the usefulness of self-regulation of brain activity in patients with fibromyalgia. Patients will use real-time functional magnetic resonance imaging (fMRI) neurofeedback to observe and regulate their own brain activity while applying mental strategies to reduce fibromyalgi...
What is the current status of trial NCT07023523?
This trial is currently recruiting. It is a NA study. The enrollment target is 36 participants. The study started on 2025-10-31. Estimated completion is 2026-07.
What conditions does trial NCT07023523 study?
This clinical trial studies the following conditions: Fibromyalgia.
What interventions are being tested in trial NCT07023523?
The interventions under investigation include: Cognitive Behavioral Therapy (BEHAVIORAL), Disease Education (BEHAVIORAL).
Who is sponsoring clinical trial NCT07023523?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07023523 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Fibromyalgia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07023523's enrollment target sits among peer trials
36 58th of 76 higher than 19 of 76 other Fibromyalgia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Fibromyalgia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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