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NCT06731608 · ClinicalTrials.gov registry record · NA

OsteoPorotic fracTure preventION System (OPTIONS) Research Study

A NA study of Osteoporosis and Lower Limb Fracture, sponsored by Brigham and Women's Hospital.

Recruiting
Registry status
NA
Development phase
1,344
Enrollment target
2
Study locations

NCT06731608: Recruiting NA study of Osteoporosis and Lower Limb Fracture, sponsored by Brigham and Women's Hospital.

NCT06731608 is a NA study of Osteoporosis and Lower Limb Fracture that is actively recruiting participants, run by Brigham and Women's Hospital. The registered enrollment target is 1,344 participants, below the 1,530-participant average among 84 other Osteoporosis trials with a reported enrollment target (12% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06731608, a NA study of Osteoporosis and Lower Limb Fracture, is actively recruiting participants, sponsored by Brigham and Women's Hospital.

RECRUITING
Registry status
NA
Development phase
1,344 participants
Enrollment target
2
Study locations

Study Summary

Osteoporosis is a disease that weakens bones so the bones may break easily. The risk for osteoporosis increases with age in both women and men. Osteoporosis affects 10 million older adults in the US. Osteoporosis is a common cause of broken bones in the hips and legs. Broken bones can lead to disability, nursing home placement, and death. Because of the dire consequences, a broken hip or leg is one of the most dreaded injuries for older adults. Many studies confirm that a simple regimen of exercise, healthy diet and bone-strengthening medications can improve overall recovery after a broken hip or leg. This regimen can prevent a person from becoming disabled, having future fractures, and even prevent death. Many older adults have surgery in a hospital after breaking a hip or leg. Then older adults go to a skilled nursing facility (SNF) for rehabilitation. Care in SNFs varies greatly. Some patients do not receive the regimen that the investigators know is most beneficial to improve bone health and recovery. Even patients who get exercise, healthy diet, and bone-strengthening medication in the SNF, may not continue with the regimen once patients go home. Therefore, the investigators want to implement and test OsteoPorotic fracTure preventION System (OPTIONS). OPTIONS is a program that will integrate the regimen into the care that is provided in SNFs and after discharge to the community. OPTONS will provide information about exercise, diet, and bone-strengthening medication. OPTIONS will provide doctors, clinical staff, patients, and care partners with the information these stakeholders need to carry out the best-practice regimen. The investigators are partnering with PointClickCare, a large cloud-based healthcare software provider, with SNFs and community care sites across the US. The investigators will include 32 SNFs from different US areas. The investigators will flip a coin to assign SNFs to the intervention (OPTIONS) or the control arm (enhanced usual care) of t

Primary Outcome

Daily Activity Scale of the Activity Measure for Post-Acute Care (AM-PAC) Daily Activity Outpatient Short Form (Low Function): The AM-PAC measures a patient's functional ability to perform daily activities, with higher scores indicating greater independence (raw scores range from 6 to 24).

Interventions

  • BEHAVIORAL OPTIONS
  • BEHAVIORAL Enhanced usual care

Study Locations (2)

Maryland

  • University of Maryland, Baltimore, Department of Epidemiology and Public Health, Division of Gerontology - Baltimore

Massachusetts

  • Brigham and Women's Hospital - Boston

Trial Details

FieldValue
Enrollment Target 1,344 participants
Start Date 2026-01-16
Est. Completion 2029-02-01
Phase NA
Brigham and Women's Hospital

937 total trials

What NCT06731608 shows while recruiting

NCT06731608 is an interventional study that assigns participants to a tested intervention. Its 1,344 participants enrollment target places it among the larger protocols in the corpus, below the 1,530-participant average among 84 other Osteoporosis trials with a reported enrollment target (12% lower).

The record links to 2 conditions, with Osteoporosis appearing as the primary indexed condition, and to 2 interventions - of which OPTIONS is the first listed.

NCT06731608 reports a single indexed study location in Maryland, Massachusetts.

Frequently Asked Questions

What is clinical trial NCT06731608 about?

NCT06731608 is a clinical study titled "OsteoPorotic fracTure preventION System (OPTIONS) Research Study". Osteoporosis is a disease that weakens bones so the bones may break easily. The risk for osteoporosis increases with age in both women and men. Osteoporosis affects 10 million older adults in the US. Osteoporosis is a common cause of broken bones in the hips and legs. Broken bones can lead to disabi...

What is the current status of trial NCT06731608?

This trial is currently recruiting. It is a NA study. The enrollment target is 1,344 participants. The study started on 2026-01-16. Estimated completion is 2029-02-01.

What conditions does trial NCT06731608 study?

This clinical trial studies the following conditions: Osteoporosis, Lower Limb Fracture.

What interventions are being tested in trial NCT06731608?

The interventions under investigation include: OPTIONS (BEHAVIORAL), Enhanced usual care (BEHAVIORAL).

Who is sponsoring clinical trial NCT06731608?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06731608 being conducted?

This trial has 2 study locations across Maryland, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Osteoporosis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06731608's enrollment target sits among peer trials

1,344 12th of 84 higher than 73 of 84 other Osteoporosis trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Osteoporosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06731608, the US trial registry maintained by the National Library of Medicine. NCT06731608 (large enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.