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NCT06483659 · ClinicalTrials.gov registry record · Phase 2
Intravenous Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy
A Phase 2 study of Postoperative Pain, sponsored by Brigham and Women's Hospital.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 152
- Enrollment target
- 1
- Study location
NCT06483659: Recruiting Phase 2 study of Postoperative Pain, sponsored by Brigham and Women's Hospital.
NCT06483659 is a Phase 2 study of Postoperative Pain that is actively recruiting participants, run by Brigham and Women's Hospital. The registered enrollment target is 152 participants, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (34% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06483659, a Phase 2 study of Postoperative Pain, is actively recruiting participants, sponsored by Brigham and Women's Hospital.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 152 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a randomized, double-blinded, placebo-controlled trial to compare the effectiveness of IV oxytocin infusion to placebo on peri-operative opioid consumption and reducing post-operative pain following a minimally invasive hysterectomy under general anesthesia.
Primary Outcome
Assess the impact of a perioperative infusion of oxytocin on postoperative pain, the average patient pain scores measured as a mean Brief Pain Inventory in PACU after laparoscopic hysterectomy in treated and untreated groups will be compared
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Oxytocin
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 152 participants |
| Start Date | 2025-06-01 |
| Est. Completion | 2026-12-01 |
| Phase | Phase 2 |
What NCT06483659 shows while recruiting
NCT06483659 is an interventional study that assigns participants to a tested intervention. The registered 152 participants enrollment target is mid-sized for trials with a published cap, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (34% lower).
The record links to 1 condition, with Postoperative Pain appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06483659 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06483659 about?
NCT06483659 is a clinical study titled "Intravenous Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy". This is a randomized, double-blinded, placebo-controlled trial to compare the effectiveness of IV oxytocin infusion to placebo on peri-operative opioid consumption and reducing post-operative pain following a minimally invasive hysterectomy under general anesthesia.
What is the current status of trial NCT06483659?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 152 participants. The study started on 2025-06-01. Estimated completion is 2026-12-01.
What conditions does trial NCT06483659 study?
This clinical trial studies the following conditions: Postoperative Pain.
What interventions are being tested in trial NCT06483659?
The interventions under investigation include: Placebo (DRUG), Oxytocin (DRUG).
Who is sponsoring clinical trial NCT06483659?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06483659 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postoperative Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06483659's enrollment target sits among peer trials
152 34th of 120 higher than 87 of 120 other Postoperative Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postoperative Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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