Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Alcohol Use Disorder: early-phase trial registry
109 of 185 indexed Alcohol Use Disorder trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #60 of 28,707 conditions by registered trial count.
185 US clinical trials · 109 currently recruiting · #60 of 28,707 conditions by registered trial count
Alcohol Use Disorder: 185 US clinical trials tracked, 109 recruiting.
Alcohol Use Disorder is the subject of 185 registered US clinical trials on ClinicalTrials.gov, 109 of them currently open to new participants. 8 are in Phase 3-4 (later-stage) and 75 in Phase 1-2 (earlier-stage). The most active sponsor is Yale University, running 13 of these trials.
Enrollment posture brief
Registry condition alcohol-use-disorder
OPEN 109 | RECR 59% | LATE 8 | EARLY 75 | RANK #60 | SPON 13
Volume-matched condition peers
Nearest open-share peer: Breast Carcinoma (59% recruiting · 107 trials)
Alcohol Use Disorder lists 109 open slots (59% of 185 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Alcohol Use Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Alcohol Use Disorder is recruiting above its size-band peers.
109 of 185 indexed trials (58.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Alcohol Use Disorder trials is spread across many organizations.
Yale University accounts for 13 of 185 trials (7%). 91 distinct sponsors appear on at least one study for this condition label.
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Typical Alcohol Use Disorder enrolment sits around 90 participants.
Median target enrolment is 90 among the 185 trials that report a genuine target (sentinel values excluded). 99 of those (53.5%) plan for fewer than 100 participants.
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Alcohol Use Disorder research is mostly interventional.
173 interventional and 12 observational studies make up this index (93.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
185 total, page 1 of 4
Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP
National Institute on Drug Abuse (NIDA)
NCT06552741
NIAAA Natural History Protocol
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT02231840
Systematic Implementation of Patient-centered Care for Alcohol Use Trial: Beyond Referral to Treatment
Kaiser Permanente
NCT06318026
A Study of Brenipatide in Participants With Alcohol Use Disorder
Eli Lilly and Company
NCT07219953
A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder
Eli Lilly and Company
NCT07219966
Removing Barriers: Community Partnering for Innovative Solutions to the Opioid Crisis
University of Michigan
NCT05665179
A Peer Recovery Coaching Intervention for Hospitalized Alcohol Use Disorder Patients
Clemson University
NCT06479681
A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners
Stanford University
NCT05619185
Trial of a Culturally Informed Brief Intervention to Reduce Alcohol Related Health Disparities and Treatment Inequities Among Latinxs
University of Texas, El Paso
NCT05800899
Enhancing Prospective Thinking in Early Recovery (HOME)
Indiana University
NCT06302413
Individual Variations of Taste and Smell Perception in Alcohol Use Disorder (AUD)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT05677321
Promoting Alcohol Treatment Engagement Post-hospitalization
Yale University
NCT05338151
TRAC-ER Intervention to Reduce Risky Alcohol Use and HIV Risk
University of Kentucky
NCT05576350
Leveraging Virtual Care Strategies to Improve Access and Treatment for Individuals With Alcohol Use Disorders
University of Michigan
NCT05594238
Brief Family Involved Treatment Telehealth
Medical University of South Carolina
NCT05674409
Emergency Medicine Peer Outreach Worker Engagement for Recovery
University of California, Los Angeles
NCT06320015
Behavioral and Functional Task Development, Implementation, and Testing
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT02108054
Cannabis' Impact on Alcohol Consumption
Brown University
NCT05389930
Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders
Evon Medics
NCT06434818
Testing a PTSD m-Health Intervention to Improve Alcohol Treatment Outcomes
Michigan State University
NCT05564663
A Study to Evaluate Mazdutide Compared With Placebo in Participants With Alcohol Use Disorder
Eli Lilly and Company
NCT06817356
Implementation of Mobile-based Programs for Alcohol Cessation in Treatment of Alcohol-associated Liver Disease
University of Wisconsin, Madison
NCT06305624
Integrated Treatment for Enhancing Growth in Recovery During Adolescence
Massachusetts General Hospital
NCT06395467
Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral Therapy for Comorbidity
University of Minnesota
NCT05117255
Orexin Receptor Antagonism for the Treatment of Alcohol Use Disorder and Stress-Related Drinking
Ohio State University
NCT07214207
Impulsivity Domains and Subjective Response
Jessica Weafer
NCT05929677
Brexpiprazole in Alcohol Use Disorder
University of Colorado, Denver
NCT04066192
Emergency Department-Initiated Medications for Alcohol Use Disorder
Yale University
NCT05827159
Alcohol and the Social Brain: an Alcohol-Administration Hyperscanning Study
University of Illinois at Urbana-Champaign
NCT06687525
Testing a Lifestyle Physical Activity Intervention for Women With Depression in Alcohol Treatment
Butler Hospital
NCT04667520
Motivation for IV Alcohol Self-Administration in Humans
University of California, Los Angeles
NCT06494891
Alcohol Treatment Outcomes Following Early vs. Standard Liver Transplant for SAH
Johns Hopkins University
NCT03845205
Guanfacine for Alcohol Use Disorder (AUD)
Indiana University
NCT06629259
Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD
NYU Langone Health
NCT06349083
Virtual Incentive Treatment for Alcohol
Washington State University
NCT06265506
Integration of Cognitive Processing Therapy and Relapse Prevention for Alcohol Use Disorder and PTSD
Texas A&M University
NCT05959434
Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment of Alcohol Use Disorder (AUD)
Brainsway
NCT07216872
Oxytocin to Enhance Integrated Treatment for AUD and PTSD
Medical University of South Carolina
NCT04523922
Alcohol Use Disorder and Cannabidiol
University of Colorado, Denver
NCT05613608
AAT for Alcohol Use Disorder in Veterans
VA Office of Research and Development
NCT05372029
Role of Phosphatidylethanol in Predicting Perioperative Outcomes of Admitted Patients at UHCMC
University Hospitals Cleveland Medical Center
NCT06864819
A Female-Specific CBT Group for Veteran Women With Alcohol Use Disorder in VA Primary Care Settings
University of Massachusetts, Worcester
NCT06118346
Electronic Harm Reduction Treatment for Alcohol
University of Washington
NCT06702007
Sex Differences in the Response to Abstinence From Alcohol.
Indiana University
NCT03827460
Donepezil and Cognitive Training for Alcohol Use Disorder (AUD)
VA Connecticut Healthcare System
NCT05042102
Image-guided, Robot Navigated Transcranial Magnetic Stimulation (IR-TMS) for Alcohol Use Disorder (AUD)
The University of Texas Health Science Center at San Antonio
NCT06648642
Leveraging Biomarkers for Personalized Treatment of Alcohol Use Disorder Comorbid With PTSD
NYU Langone Health
NCT03667846
Alcohol Research in HIV: Relapse Prevention
Johns Hopkins University
NCT05163301
Pregnenolone for the Treatment of Alcohol Use Disorder
Yale University
NCT05781009
Imaging Traumatic Stress and Alcohol Use Disorder With [18F]Bavarostat
Yale University
NCT06371404
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 26 |
| Phase 2 | 49 |
| Phase 3 | 5 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Alcohol Use Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Alcohol Use Disorder trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Alcohol Use Disorder page
185 registered trials, 109 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 109 Alcohol Use Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Yale University sponsors the most Alcohol Use Disorder trials on record, review their full trial history before evaluating a specific study. See Yale University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Alcohol Use Disorder condition card totals 185 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.