Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Breast Carcinoma

Open-data reference.

107 US clinical trials · 63 currently recruiting

Active & Recent Trials

RECRUITING NA 24,000 participants

The Vanguard Study: Testing a New Way to Screen for Cancer

National Cancer Institute (NCI)

NCT06995898

RECRUITING 10,000 participants

Mammography, Early Detection Biomarkers, Risk Assessment, and Imaging Technologies, MERIT Study

M.D. Anderson Cancer Center

NCT03408353

RECRUITING 5,000 participants

Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated With Proton Therapy

M.D. Anderson Cancer Center

NCT00991094

RECRUITING 4,500 participants

Integrating Molecular Pathology, Radiology, and Genetics to Improve Breast Cancer Risk

Mayo Clinic

NCT07207564

RECRUITING NA 2,067 participants

The Ohio State University (OSU) SCREEN Community Program

Ohio State University Comprehensive Cancer Center

NCT06666192

RECRUITING 2,000 participants

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

Wake Forest University Health Sciences

NCT06418204

RECRUITING 2,000 participants

Collection of Specimens and Clinical Data for Patients With Recurrent or Metastatic Breast Cancer or Male Breast Cancer

Mayo Clinic

NCT06217874

RECRUITING NA 1,800 participants

Cancer Genetic Testing in Ethnic Populations

Mayo Clinic

NCT04475640

RECRUITING 960 participants

Impact of Dietary Inflammatory Potential on Breast Cancer Risk

Ohio State University Comprehensive Cancer Center

NCT05178498

RECRUITING NA 800 participants

Access to Genetic Testing in Underserved Patients With Cancer

University of Southern California

NCT06422455

RECRUITING NA 800 participants

Utilizing Advocates and Supporters to Increase Lung Cancer Screening Rates in Eligible Participants

Jonsson Comprehensive Cancer Center

NCT05978128

RECRUITING 750 participants

Comparison of Synthetic Mammography Versus Full-Field Digital Mammography in Image Interpretation and Performance Metrics

M.D. Anderson Cancer Center

NCT05056818

RECRUITING 575 participants

Whole Exome Sequencing in Finding Causative Variants in Germline DNA Samples From Patients With Peripheral Neuropathy Receiving Paclitaxel for Breast Cancer

National Cancer Institute (NCI)

NCT02610439

RECRUITING 550 participants

Quantitative Microvasculature Imaging for Breast Cancer Detection and Monitoring

Mayo Clinic

NCT04799535

RECRUITING 490 participants

A Validation Study to Determine Concordance of Liquid Biopsy and Breast Cancer Diagnosis

University of Southern California

NCT06336928

RECRUITING NA 410 participants

Functional Near-Infrared Spectroscopy and Virtual Reality Relaxation Programs for Pain Management in Patients With Cancer

Roswell Park Cancer Institute

NCT06456411

RECRUITING NA 410 participants

Mobile Health for Adherence in Breast Cancer Patients

ECOG-ACRIN Cancer Research Group

NCT06112613

RECRUITING NA 400 participants

Photoacoustic Imaging of the Breast in Patients With Breast Cancer and Healthy Subjects

Roswell Park Cancer Institute

NCT03897270

RECRUITING Phase 2 400 participants

EMBRACE: Exercising Together

OHSU Knight Cancer Institute

NCT06049355

RECRUITING 354 participants

Whole Exome Sequencing in Finding Causative Variants in Germline DNA Samples From Patients With Hypertension Receiving Bevacizumab for Breast Cancer

National Cancer Institute (NCI)

NCT02610413

RECRUITING Phase 1 300 participants

Serial Imaging of the Novel Radiotracer [^18F] FLuorthanatrace ([^18F] FTT) by PET/CTF

M.D. Anderson Cancer Center

NCT03604315

RECRUITING 290 participants

Neutrophil Extracellular Traps Formation in Breast Cancer Patients Taking Tamoxifen

M.D. Anderson Cancer Center

NCT05056857

RECRUITING Phase 3 285 participants

A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People With Breast Cancer

Memorial Sloan Kettering Cancer Center

NCT06144164

RECRUITING NA 244 participants

Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy

Wake Forest University Health Sciences

NCT05703269

RECRUITING Phase 2 200 participants

Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

National Cancer Institute (NCI)

NCT06184750

RECRUITING 200 participants

TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer

Mayo Clinic

NCT05507879

RECRUITING NA 200 participants

Virtual Support Platform (HERCaRE Application) for the Improvement of Survivorship Among Black Breast Cancer Survivors

Mayo Clinic

NCT07126522

RECRUITING NA 175 participants

A Synthetic Lethality-Focused Algorithm to Identify Therapeutic Options in Advanced Metastatic Breast Cancer (SYNTHESIS-Breast)

National Cancer Institute (NCI)

NCT07067138

RECRUITING 170 participants

Endocrine Therapy-Induced Alopecia in Postmenopausal and Premenopausal Female Breast Cancer Patients

Mayo Clinic

NCT05612100

RECRUITING 162 participants

Whole Exome Sequencing in Finding Causative Variants in Germline DNA Samples From Patients With Congestive Heart Failure Receiving Therapy for Breast Cancer

National Cancer Institute (NCI)

NCT02610426

RECRUITING 150 participants

Breast Cancer Screening Adherence for Women at Moderate Risk for Breast Cancer

University of Southern California

NCT07076147

RECRUITING 150 participants

Postoperative Outcomes and Patient Satisfaction With Mayo Clinic Florida Care Hotel After Mastectomy and Tissue Expander Placement

Mayo Clinic

NCT06783179

RECRUITING Phase 2 140 participants

Study of Aerobic Training for People Receiving Chemotherapy for Breast Cancer

Memorial Sloan Kettering Cancer Center

NCT05716893

RECRUITING NA 130 participants

Home-based Respiratory Muscle Training for Minimizing Side Effects in Patients Undergoing Treatment for Breast Cancer

Roswell Park Cancer Institute

NCT05787834

RECRUITING NA 126 participants

A Patient Navigation Program for Addressing Disparities in Breast Cancer Care

Roswell Park Cancer Institute

NCT06350500

RECRUITING NA 125 participants

A Post-treatment Supportive Service Program for the Transition Into Survivorship for Black Women Breast Cancer Survivors in Western New York

Roswell Park Cancer Institute

NCT06833255

RECRUITING Phase 2 120 participants

Hypofractionated Radiotherapy Before or After Breast Surgery for Treatment of Patients With Non-Metastatic Breast Cancer

Mayo Clinic

NCT06635980

RECRUITING Phase 2 120 participants

Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors

City of Hope Medical Center

NCT06731894

RECRUITING Phase 1 100 participants

Contrast Enhanced Ultrasound Medical Imaging for Identifying Breast Masses

University of Southern California

NCT06171607

RECRUITING Phase 2 100 participants

Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer

Mayo Clinic

NCT05557877

RECRUITING NA 100 participants

An Imaging Technology, Contrast-Enhanced Mammography, in Predicting Breast Cancer

M.D. Anderson Cancer Center

NCT04871139

RECRUITING 100 participants

The Sleep After Breast Cancer (ABC) Study - Examining Sleep Changes and Biomarkers Among Breast Cancer Patients

Ohio State University Comprehensive Cancer Center

NCT07341503

RECRUITING Phase 2 82 participants

Ultra-hypofractionated Whole Breast Irradiation With Lumpectomy Cavity Boost for the Treatment of Stage I-III Breast Cancer

City of Hope Medical Center

NCT06954831

RECRUITING NA 80 participants

A Self-Monitoring Platform for Tracking Medication Safety and Concerns in Cancer Patients

University of Michigan Rogel Cancer Center

NCT07291414

RECRUITING Phase 2 80 participants

Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

National Cancer Institute (NCI)

NCT05941520

RECRUITING NA 75 participants

A Patient Navigation Intervention for the Improvement of Risk Management Among Women at High Risk of Breast Cancer

Ohio State University Comprehensive Cancer Center

NCT06950008

RECRUITING Phase 2 66 participants

Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction

National Cancer Institute (NCI)

NCT06195306

RECRUITING NA 66 participants

Contrast Enhanced Spectral Mammography for the Evaluation of Pathologic Nipple Discharge

M.D. Anderson Cancer Center

NCT05056844

RECRUITING Early Phase 1 55 participants

3D Ultrasound for the Imaging of Lymph Nodes in Patients With Breast Cancer

Mayo Clinic

NCT05704283

RECRUITING NA 50 participants

A 3D-Printed External Breast Prosthesis for the Improvement of Patient-reported Outcomes Among Breast Cancer Patients That Underwent a Mastectomy Without Reconstruction

Mayo Clinic

NCT07047872

RECRUITING 50 participants

Adding a Genetic Risk Evaluation to Standard Breast Cancer Risk Assessment for African American and Hispanic Women

Mayo Clinic

NCT05755269

RECRUITING NA 45 participants

Primary Breast Oligoprogressive Sites Treated With Radiotherapy to Obviate the Need to Change Systemic Therapy

Mayo Clinic

NCT06055881

RECRUITING NA 40 participants

A Digital Health Intervention to Improve Symptoms and Physical Activity During Breast Radiation

University of Washington

NCT06772181

RECRUITING Early Phase 1 40 participants

MUSE-S Headband System for Improving Anxiety and Insomnia Among Breast Cancer Survivors

Mayo Clinic

NCT06274034

RECRUITING 30 participants

Surviving Daily Life

Thomas Jefferson University

NCT07054723

RECRUITING Phase 1 30 participants

Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers

Jonsson Comprehensive Cancer Center

NCT07118176

RECRUITING 30 participants

A Study Comparing Cancer Imaging Approaches in People With Lobular Breast Cancer

Memorial Sloan Kettering Cancer Center

NCT06557148

RECRUITING Phase 2 27 participants

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

Mayo Clinic

NCT07285044

RECRUITING NA 26 participants

Effects of White Button Mushroom on Inflammation in Obese Postmenopausal Women at High Risk of Breast Cancer

City of Hope Medical Center

NCT04913064

RECRUITING Phase 1 24 participants

Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer

City of Hope Medical Center

NCT06130826

RECRUITING 20 participants

Collecting Patient-Reported Experiences With Radiation Dermatitis in Breast Cancer Patients Undergoing Radiotherapy

Mayo Clinic

NCT06953245

RECRUITING NA 20 participants

CIPN Decision Aid for the Improvement of Chemotherapy Decision Making in Patients With Breast Cancer

University of Michigan Rogel Cancer Center

NCT06915168

RECRUITING 12 participants

Temporal Immunologic Changes With Hypofractionated Radiation-Induced DNA Damage in Breast Cancer

M.D. Anderson Cancer Center

NCT05406232

ACTIVE NOT RECRUITING Phase 2 6,452 participants

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

National Cancer Institute (NCI)

NCT02465060

ACTIVE NOT RECRUITING Phase 3 3,177 participants

Breast Cancer WEight Loss Study (BWEL Study)

Alliance for Clinical Trials in Oncology

NCT02750826

ACTIVE NOT RECRUITING NA 874 participants

Genetic Counseling Patient Preference Intervention Versus Conventional Genetic Counseling for Women at Elevated Risk for Breast Cancer

Ohio State University Comprehensive Cancer Center

NCT05325151

ACTIVE NOT RECRUITING Phase 2 849 participants

Study in Metastatic Breast Cancer Patients Receiving Eftilagimod Alpha or Placebo in Combination with Paclitaxel Chemotherapy

Immutep S.A.S.

NCT05747794

ACTIVE NOT RECRUITING NA 465 participants

HOPE-Genomics Intervention for the Improvement of Cancer Patient Knowledge of Genomics

City of Hope Medical Center

NCT04905082

ACTIVE NOT RECRUITING NA 337 participants

Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members

M.D. Anderson Cancer Center

NCT02194387

ACTIVE NOT RECRUITING Phase 3 300 participants

Studying the Effect of Denosumab on Preventing Breast Cancer in Women With a BRCA1 Germline Mutation

Alliance for Clinical Trials in Oncology

NCT04711109

ACTIVE NOT RECRUITING NA 261 participants

Survivorship Care Plans and Telehealth Education for the Improvement of Access to Cancer Survivorship, the IMPACT Study

Fred Hutchinson Cancer Center

NCT04081779

ACTIVE NOT RECRUITING Phase 3 216 participants

Testing the Application of Mepitel Film During Radiation Therapy to Reduce Radiation Related Redness and Peeling in Breast Cancer Patients Following Mastectomy

Alliance for Clinical Trials in Oncology

NCT04989504

ACTIVE NOT RECRUITING 140 participants

Long Term Followup of Patients Enrolled in MC1137, BEAUTY Study

Mayo Clinic

NCT05703399

ACTIVE NOT RECRUITING 140 participants

Evaluating Mechanical Properties of Post-Mastectomy Skin Flaps to Estimate Reconstruction Risks, the EMPOWER Study

M.D. Anderson Cancer Center

NCT06584396

ACTIVE NOT RECRUITING NA 134 participants

Single Fraction Accelerated Partial Breast Irradiation vs. Five Fraction Accelerated Partial Breast Irradiation for Low-risk Stage 0 and I Breast Carcinoma

Washington University School of Medicine

NCT04849871

ACTIVE NOT RECRUITING Phase 1 134 participants

A Phase 1 Study of ATV-1601 in Patients With Advanced Cancer That Have AKT1 E17K Mutations

Atavistik Bio

NCT07038369

ACTIVE NOT RECRUITING Phase 2 120 participants

Phase II Breast Ca Carboplatin + Paclitaxel With Pertuzumab + Trastuzumab or Bevacizumab

University of California, Irvine

NCT02436993

ACTIVE NOT RECRUITING Phase 1 94 participants

Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction

National Cancer Institute (NCI)

NCT01366144

ACTIVE NOT RECRUITING NA 77 participants

Three Fraction Accelerated Partial Breast Irradiation as the Sole Method of Radiation Therapy for Low-risk Stage 0 and I Breast Carcinoma

Washington University School of Medicine

NCT03612648

ACTIVE NOT RECRUITING 59 participants

Contrast-Enhanced Mammography for the Evaluation of Mammographic Microcalcifications

M.D. Anderson Cancer Center

NCT05046301

ACTIVE NOT RECRUITING NA 50 participants

Lifestyle Intervention for the Reduction of Breast Cancer Risk in Normal Weight Women

M.D. Anderson Cancer Center

NCT04267796

ACTIVE NOT RECRUITING Phase 2 42 participants

Carboplatin and Paclitaxel With or Without Panitumumab in Treating Patients With Invasive Triple Negative Breast Cancer

M.D. Anderson Cancer Center

NCT02876107

ACTIVE NOT RECRUITING Phase 2 36 participants

A Radiotracer ([18F]FluorThanatrace) by PET/CT for the Imaging of Breast Cancer

M.D. Anderson Cancer Center

NCT05226663

ACTIVE NOT RECRUITING NA 35 participants

Patient-Specific Decision Aid System for Shared Decision Making About Breast Reconstruction

M.D. Anderson Cancer Center

NCT05130580

ACTIVE NOT RECRUITING Phase 2 30 participants

Nivolumab, Ipilimumab, and Bicalutamide in Human Epidermal Growth Factor (HER) 2 Negative Breast Cancer Patients

Providence Health & Services

NCT03650894

ACTIVE NOT RECRUITING NA 30 participants

An Investigational Surgical Procedure (Vascularized Lymph Node Transfer) in Reducing the Risk of Lymphedema in Patients With Breast Cancer Undergoing Breast Reconstruction

M.D. Anderson Cancer Center

NCT03990610

ACTIVE NOT RECRUITING NA 30 participants

Mobile-Health Delivery of Lifestyle Interventions for Women With Breast Cancer

M.D. Anderson Cancer Center

NCT05132296

ACTIVE NOT RECRUITING Early Phase 1 29 participants

Experimental PET Imaging Scans Before Cancer Surgery to Study the Amount of PET Tracer Accumulated in Normal and Cancer Tissues

Jonsson Comprehensive Cancer Center

NCT04147494

ACTIVE NOT RECRUITING Early Phase 1 27 participants

First-in-Human Positron Emission Tomography Study Using the 18F-αvβ6-Binding-Peptide

Julie L. Sutcliffe, Ph.D

NCT03164486

ACTIVE NOT RECRUITING Phase 1 27 participants

Safety and Immune Response to a Mammaglobin-A DNA Vaccine In Breast Cancer Patients Undergoing Neoadjuvant Endocrine Therapy

Washington University School of Medicine

NCT02204098

ACTIVE NOT RECRUITING Phase 2 8 participants

Neoadjuvant Endocrine Therapy in ER-positive, HER2-negative Early Stage Breast Cancer

Irada Ibrahim-zada

NCT05150652

COMPLETED 1,916 participants

Incidence of Cancer in Women at Increased Genetic Risk of Ovarian Cancer

Gynecologic Oncology Group

NCT01139957

COMPLETED Phase 3 1,363 participants

Treatment of Refractory Nausea and Vomiting in Patients With Breast Cancer

University of Rochester NCORP Research Base

NCT03367572

COMPLETED 324 participants

CARE: Cancer Risk Perception and Women of Color

Mayo Clinic

NCT06036875

COMPLETED Phase 1 230 participants

Pro-Active Genetic Testing in Patients With Solid Tumors, Inherit Study

Mayo Clinic

NCT04456140

COMPLETED Phase 2 230 participants

Bupropion Hydrochloride in Improving Sexual Desire in Women With Breast or Gynecologic Cancer

NRG Oncology

NCT03180294

COMPLETED Phase 1 150 participants

A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors

Xencor

NCT03517488

COMPLETED 85 participants

A Correlational Study: Breast Cancer-related Chest Wall Lymphedema, Quality of Life, and Shoulder Function

Mayo Clinic

NCT06285747

COMPLETED Early Phase 1 83 participants

MR Correlated Spectroscopic Imaging for Diagnosing Breast Cancer

Jonsson Comprehensive Cancer Center

NCT06090630

COMPLETED NA 66 participants

Fractional CO2 Laser Therapy for Survivors of Breast Malignancies

Ohio State University Comprehensive Cancer Center

NCT03307044

Phase Distribution

PhaseTrial count
Early Phase 1 15
Phase 2 18
Phase 3 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Breast Carcinoma Trial Landscape

ClinicalTrials.gov lists 107 US studies indexed under Breast Carcinoma, and 63 of those are currently open to recruitment — roughly 59% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Breast Carcinoma shows 5 late-stage studies (Phase 3 and Phase 4 combined) alongside 33 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Breast Carcinoma is led by Mayo Clinic with 21 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 100 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Breast Carcinoma?

PlainTrial tracks 107 US clinical trials for Breast Carcinoma, of which 63 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Breast Carcinoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →