Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05959434 · ClinicalTrials.gov registry record · Phase 2

Integration of Cognitive Processing Therapy and Relapse Prevention for Alcohol Use Disorder and PTSD

A Phase 2 study of Alcohol Use Disorder and Posttraumatic Stress Disorder, sponsored by Texas A&M University.

Recruiting
Registry status
Phase 2
Development phase
200
Enrollment target
2
Study locations

NCT05959434 is a Phase 2 study of Alcohol Use Disorder and Posttraumatic Stress Disorder that is actively recruiting participants, run by Texas A&M University. The registered enrollment target is 200 participants, below the 327-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (39% lower). The trial reports 2 study locations across 2 states.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05959434, a Phase 2 study of Alcohol Use Disorder and Posttraumatic Stress Disorder, is actively recruiting participants, sponsored by Texas A&M University.

RECRUITING
Registry status
Phase 2
Development phase
200 participants
Enrollment target
2
Study locations

Study Summary

The goal of this clinical trial is to test the efficacy of a novel integrative cognitive-behavioral intervention in patients with posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD). Specific Aim 1: Examine the efficacy of CPT-RP, as compared to RP alone, in reducing alcohol frequency (percent days drinking) and quantity (drinks per drinking day) as measured by the Timeline Follow-Back (TLFB). Specific Aim 2: Examine the efficacy of CPT-RP, as compared to RP alone, in reducing PTSD symptoms as measured by the Clinician Administered PTSD Scale (CAPS-5). Specific Aim 3: Use ecological momentary assessment (EMA) to evaluate intervention effects on daily alcohol-related cognitions and behaviors through real-time associations with PTSD symptomatology and distress tolerance. Researchers will compare integrative CPT+RP with RP-alone to see if CPT+RP is more efficacious in reducing alcohol use and PTSD symptom severity.

Conditions Studied

Alcohol Use Disorder Posttraumatic Stress Disorder

Interventions

  • BEHAVIORAL Cognitive Processing Therapy + Relapse Prevention
  • BEHAVIORAL Relapse Prevention

Study Locations (2)

South Carolina

  • Medical University of South Carolina - Charleston

Texas

  • Texas A&M University - College Station

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2024-04-01
Est. Completion 2028-07-31
Phase Phase 2

Sponsor

Texas A&M University

95 total trials

Interested in This Trial?

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05959434

The ClinicalTrials.gov registry entry for NCT05959434 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 327-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (39% lower). The listed sponsor is Texas A&M University, which has 95 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Alcohol Use Disorder appearing as the primary indexed condition, and to 2 interventions - of which Cognitive Processing Therapy + Relapse Prevention is the first listed.

NCT05959434 reports 2 study locations spanning 2 distinct geographic areas - top geographies include South Carolina, Texas.

Frequently Asked Questions

What is clinical trial NCT05959434 about?

NCT05959434 is a clinical study titled "Integration of Cognitive Processing Therapy and Relapse Prevention for Alcohol Use Disorder and PTSD". The goal of this clinical trial is to test the efficacy of a novel integrative cognitive-behavioral intervention in patients with posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD). Specific Aim 1: Examine the efficacy of CPT-RP, as compared to RP alone, in reducing alcohol frequen...

What is the current status of trial NCT05959434?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 200 participants. The study started on 2024-04-01. Estimated completion is 2028-07-31.

What conditions does trial NCT05959434 study?

This clinical trial studies the following conditions: Alcohol Use Disorder, Posttraumatic Stress Disorder.

What interventions are being tested in trial NCT05959434?

The interventions under investigation include: Cognitive Processing Therapy + Relapse Prevention (BEHAVIORAL), Relapse Prevention (BEHAVIORAL).

Who is sponsoring clinical trial NCT05959434?

This trial is sponsored by Texas A&M University, which has 95 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05959434 being conducted?

This trial has 2 study locations across South Carolina, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Alcohol Use Disorder

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Explore more on PlainTrial

Alcohol Use Disorder

All registered trials for this condition

Posttraumatic Stress Disorder

All registered trials for this condition

South Carolina

All trials with a study site in South Carolina

Recruiting now

Find trials open to new participants near you

Rankings

Top sponsors, conditions, and phases

Read our methodology - how this data is sourced, computed, and verified.

Related

Browse all → | Rankings →
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.