Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05117255 · ClinicalTrials.gov registry record · NA

Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral Therapy for Comorbidity

A NA study of Depression and Alcohol Use Disorder, sponsored by University of Minnesota.

Recruiting
Registry status
NA
Development phase
256
Enrollment target
1
Study location

NCT05117255: Recruiting NA study of Depression and Alcohol Use Disorder, sponsored by University of Minnesota.

NCT05117255 is a NA study of Depression and Alcohol Use Disorder that is actively recruiting participants, run by University of Minnesota. The registered enrollment target is 256 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (67% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05117255, a NA study of Depression and Alcohol Use Disorder, is actively recruiting participants, sponsored by University of Minnesota.

RECRUITING
Registry status
NA
Development phase
256 participants
Enrollment target
1
Study location

Study Summary

This project is designed to determine if a computer-delivered cognitive-behavioral treatment can improve the otherwise poor alcohol use disorder treatment outcomes for individuals with a co-occurring anxiety disorder. In the past, the investigators showed that this treatment does improve outcomes for these individuals when delivered by a therapist. If the present work shows that the computer-delivered version is also effective, it would provide an inexpensive program with virtually unlimited scalability to enable access to the treatment by many more individuals than is currently the case.

Primary Outcome

a ratio expressed as a percent of the days the individual drank 5 (for men) or 4 (for women) or more drinks to the total number of days over the follow-up period in which drinking was possible.

Conditions Studied

Depression Alcohol Use Disorder Generalized Anxiety Disorder Social Anxiety Disorder Panic Disorder

Interventions

  • BEHAVIORAL Negative Emotions and Addiction Tools Program (NEAT)- Cognitive Behavioral Therapy
  • BEHAVIORAL Progressive Muscle Relaxation Training (PMRT)

Study Locations (1)

Minnesota

  • Lodging Plus Program, Fairview Hospital - Minneapolis

Trial Details

FieldValue
Enrollment Target 256 participants
Start Date 2022-01-04
Est. Completion 2027-03-01
Phase NA
University of Minnesota

966 total trials

What NCT05117255 shows while recruiting

NCT05117255 is an interventional study that assigns participants to a tested intervention. The registered 256 participants enrollment target is mid-sized for trials with a published cap, below the 786-participant average among 679 other Depression trials with a reported enrollment target (67% lower).

The record links to 5 conditions, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Negative Emotions and Addiction Tools Program (NEAT)- Cognitive Behavioral Therapy is the first listed.

NCT05117255 reports a single indexed study location in Minnesota.

Frequently Asked Questions

What is clinical trial NCT05117255 about?

NCT05117255 is a clinical study titled "Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral Therapy for Comorbidity". This project is designed to determine if a computer-delivered cognitive-behavioral treatment can improve the otherwise poor alcohol use disorder treatment outcomes for individuals with a co-occurring anxiety disorder. In the past, the investigators showed that this treatment does improve outcomes fo...

What is the current status of trial NCT05117255?

This trial is currently recruiting. It is a NA study. The enrollment target is 256 participants. The study started on 2022-01-04. Estimated completion is 2027-03-01.

What conditions does trial NCT05117255 study?

This clinical trial studies the following conditions: Depression, Alcohol Use Disorder, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder.

What interventions are being tested in trial NCT05117255?

The interventions under investigation include: Negative Emotions and Addiction Tools Program (NEAT)- Cognitive Behavioral Therapy (BEHAVIORAL), Progressive Muscle Relaxation Training (PMRT) (BEHAVIORAL).

Who is sponsoring clinical trial NCT05117255?

This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05117255 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Depression

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05117255's enrollment target sits among peer trials

256 171st of 679 higher than 508 of 679 other Depression trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02464696 · 256 participants · NA

    Non-invasive Ventilation in Reducing the Need for Intubation in Patients With Cancer and Respiratory Failure

  • NCT03793062 · 256 participants

    Genetic and Epigenetic Basis of Chronic Wounds

  • NCT04322318 · 256 participants · Phase 2

    A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

  • NCT04468360 · 256 participants · Phase 2

    Facilitation of Extinction Retention and Reconsolidation Blockade in PTSD

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT06358040 · started 2026-10 · NA

    Opioid Dispenser for Microdiscectomy/Laminectomy

More recruiting context for NCT05117255

Source: ClinicalTrials.gov NCT05117255, the US trial registry maintained by the National Library of Medicine. NCT05117255 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.