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NCT06629259 · ClinicalTrials.gov registry record · Phase 2

Guanfacine for Alcohol Use Disorder (AUD)

A Phase 2 study of Alcohol Use Disorder, sponsored by Indiana University.

Recruiting
Registry status
Phase 2
Development phase
200
Enrollment target
2
Study locations

NCT06629259 is a Phase 2 study of Alcohol Use Disorder that is actively recruiting participants, run by Indiana University. The registered enrollment target is 200 participants, below the 327-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (39% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT06629259, a Phase 2 study of Alcohol Use Disorder, is actively recruiting participants, sponsored by Indiana University.

RECRUITING
Registry status
Phase 2
Development phase
200 participants
Enrollment target
2
Study locations

Study Summary

The investigators assess whether guanfacine extended release (GXR; 3mg/d) compared with placebo (PBO) will attenuate drinking and drinking-related factors in N=200 men and women with Alcohol Use Disorder (AUD) across 12-weeks.

Conditions Studied

Alcohol Use Disorder

Interventions

  • DRUG Placebo
  • DRUG Guanfacine Extended Release (XR)

Study Locations (2)

Indiana

  • The Stark Neuroscience Building (Goodman Hall) - Indianapolis

New Jersey

  • Rutgers School of Health Professionals - Newark

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2025-09-01
Est. Completion 2029-09-07
Phase Phase 2

Sponsor

Indiana University

890 total trials

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What the Registry Record Tells You About NCT06629259

The ClinicalTrials.gov registry entry for NCT06629259 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 327-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (39% lower). The listed sponsor is Indiana University, which has 890 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Alcohol Use Disorder appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06629259 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Indiana, New Jersey.

Frequently Asked Questions

What is clinical trial NCT06629259 about?

NCT06629259 is a clinical study titled "Guanfacine for Alcohol Use Disorder (AUD)". The investigators assess whether guanfacine extended release (GXR; 3mg/d) compared with placebo (PBO) will attenuate drinking and drinking-related factors in N=200 men and women with Alcohol Use Disorder (AUD) across 12-weeks.

What is the current status of trial NCT06629259?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 200 participants. The study started on 2025-09-01. Estimated completion is 2029-09-07.

What conditions does trial NCT06629259 study?

This clinical trial studies the following conditions: Alcohol Use Disorder.

What interventions are being tested in trial NCT06629259?

The interventions under investigation include: Placebo (DRUG), Guanfacine Extended Release (XR) (DRUG).

Who is sponsoring clinical trial NCT06629259?

This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06629259 being conducted?

This trial has 2 study locations across Indiana, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.