Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Smoking Cessation: full-pipeline trial registry
57 of 189 indexed Smoking Cessation trials are currently recruiting.
Corpus placement: #57 of 28,707 conditions by registered trial count.
189 US clinical trials · 57 currently recruiting · #57 of 28,707 conditions by registered trial count
Smoking Cessation: 189 US clinical trials tracked, 57 recruiting.
Smoking Cessation is the subject of 189 registered US clinical trials on ClinicalTrials.gov, 57 of them currently open to new participants. 33 are in Phase 3-4 (later-stage) and 30 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, San Francisco, running 10 of these trials.
Enrollment posture brief
Registry condition smoking-cessation
OPEN 57 | RECR 30% | LATE 33 | EARLY 30 | RANK #57 | SPON 10
Volume-matched condition peers
Nearest open-share peer: Heart Diseases (30% recruiting · 86 trials)
Smoking Cessation lists 57 open slots (30% of 189 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Smoking Cessation on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
Smoking Cessation is recruiting below its size-band peers.
57 of 189 indexed trials (30.2%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
Sponsorship of Smoking Cessation trials is spread across many organizations.
University of California, San Francisco accounts for 10 of 189 trials (5.3%). 84 distinct sponsors appear on at least one study for this condition label.
-
Typical Smoking Cessation enrolment sits around 200 participants.
Median target enrolment is 200 among the 189 trials that report a genuine target (sentinel values excluded). 71 of those (37.6%) plan for fewer than 100 participants.
-
Smoking Cessation research is mostly interventional.
181 interventional and 8 observational studies make up this index (95.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
189 total, page 1 of 4
CONNECT Cancer Survivors With Tobacco Treatment
Washington University School of Medicine
NCT07020273
Refer2Quit: Evaluating a Proactive, Tailored, Population Health Approach for Tobacco Treatment for Household Smokers Through a Pediatric Care Network
Children's Hospital of Philadelphia
NCT06582693
Veteran Social Support for Enhancing Use of Smoking Cessation Treatment
VA Office of Research and Development
NCT05868421
Collection of Airway, Blood and/or Urine Specimens From Subjects for Research Studies
Weill Medical College of Cornell University
NCT01776398
Testing the mHealth App Intervention for Nondaily Smokers "SiS4"
Massachusetts General Hospital
NCT06678243
Scalable TELeheaLth Cancer CARe: The STELLAR Program to Treat Cancer Risk Behaviors
Northwestern University
NCT05687604
Family-Based Financial Incentives Intervention for Smoking Cessation
Mayo Clinic
NCT06556433
Tobacco Education and Lung Health Study (TEAL)
Georgetown University
NCT06290869
Bladder Cancer Screening Trial
University of Texas Southwestern Medical Center
NCT05646485
Personalized Tobacco Treatment in Primary Care (MOTIVATE)
Washington University School of Medicine
NCT05846841
Baby Steps III: Testing a Clinician and Patient Intervention to Promote Smoking Cessation Among Pregnant Women
Duke University
NCT04985903
Take A Break - Rural
Wake Forest University Health Sciences
NCT05790486
Overcoming Nicotine Dependence to Enable Quitting
Rush University Medical Center
NCT05513872
Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia
University of Virginia
NCT05660525
Healthy Family Project: Tobacco Use and Smoke Exposure in Asian American Communities
University of California, San Francisco
NCT07049757
Enhancing Smoking Cessation Via Telehealth Options in Primary Care
Medical University of South Carolina
NCT05493254
Smoking Cessation Program in the Construction Sector
University of Miami
NCT06098144
Urban and Reservation Implementation of All Nations Breath of Life
Lehigh University
NCT04931810
Improving Smoking Abstinence Outcomes in the African American Community Through Extended Treatment
University of Kansas Medical Center
NCT05732272
The Avenues Study: Dual Use Cessation
University of Wisconsin, Madison
NCT06474299
Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical Care
New York University
NCT06598397
Technology Assisted Motivational Interviewing
University of California, San Francisco
NCT06713603
Smoking Cessation Pharmacotherapy-Nurse Practitioner Led Tobacco Treatment Team Study
Baystate Medical Center
NCT05733767
American Indian Smokefree Native RCT
Masonic Cancer Center, University of Minnesota
NCT06544811
Actívatexto: Advancing Smoking Cessation and Physical Activity Among Latinos
University of Rochester
NCT06926608
V+PSF-M for Tobacco Cessation in HIV Care in India
University of Colorado, Denver
NCT05786547
Quitting Matters Human Immunodeficiency Virus Hybrid Trial
Wake Forest University Health Sciences
NCT06883097
The Options 2 Study
University of Wisconsin, Madison
NCT06595459
Investigating Novel Smoking Cessation Primary Care Interventions in Rural Environments
Medical University of South Carolina
NCT05764759
Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children
University of Minnesota
NCT04783857
Intervening to Promote Tobacco Cessation Following Psychiatric Hospitalization
University of Texas at Austin
NCT05672914
Wellness Intervention for Smoking and HIV
University of Arizona
NCT04725617
CONNECTing to LungCare
University of California, San Francisco
NCT06213532
Precision Treatment to Promote Smoking Cessation and Survival in Oncology Patients
Washington University School of Medicine
NCT07166120
New Strategies to Enhance Smoking Cessation
University of Chicago
NCT06751927
Creation of an Infrastructure to Support Delivery of mHealth Interventions for Cancer Patients
H. Lee Moffitt Cancer Center and Research Institute
NCT06909357
Re-Connect Application for Smoking Cessation
Rowan University
NCT05224154
Quit-Smoking Study for Native Hawaiians
University of Hawaii
NCT07075575
Examining the Effects of Cytisinicline on Neural Substrates of Cigarette Cue-reactivity
University of California, Los Angeles
NCT06617312
Clinical Research Evaluating Smoking Cessation With E-Cigarettes and Nicotine Therapy
Brown University
NCT06948058
ACT Lung Health Intervention: Phase Two
Dana-Farber Cancer Institute
NCT06945120
Remote Smoking Cessation in Hospitalized Cardiac Patients
University of Vermont Medical Center
NCT05738408
Metabolism-Informed Care to Aid Alaska Native People to Quit Smoking (QUIT)
Southcentral Foundation
NCT06556238
Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches
Medical University of South Carolina
NCT06678789
Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)
The University of Texas Health Science Center, Houston
NCT05276050
Mindfulness-based Ecological Momentary Intervention for Smoking Cessation Among Cancer Survivors
Rutgers, The State University of New Jersey
NCT07210567
Healing Within: Mindfulness Smoking Cessation Intervention
National Heart, Lung, and Blood Institute (NHLBI)
NCT07013968
Smoking Cessation Intervention for American Indian Women Experiencing Intimate Partner Violence
Black Hills Center for American Indian Health
NCT06357767
Reducing Tobacco Smoking: a Transcranial Direct Current Stimulation (TDCS) Telehealth Study
Wake Forest University Health Sciences
NCT05460676
Concurrent vs. Sequential Cessation of Dual Cigarette and E-cigarette Use
Yale University
NCT06027840
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 15 |
| Phase 2 | 15 |
| Phase 3 | 14 |
| Phase 4 | 19 |
Top Sponsors
Named interventions
Most-linked intervention names on Smoking Cessation records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Smoking Cessation trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Smoking Cessation page
189 registered trials, 57 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 57 Smoking Cessation trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of California, San Francisco sponsors the most Smoking Cessation trials on record, review their full trial history before evaluating a specific study. See University of California, San Francisco's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Smoking Cessation condition card totals 189 registered trials; most-linked intervention Varenicline; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.