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NCT06494891 · ClinicalTrials.gov registry record · Phase 2
Motivation for IV Alcohol Self-Administration in Humans
A Phase 2 study of Alcohol Use Disorder, sponsored by University of California, Los Angeles.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 210
- Enrollment target
- 1
- Study location
NCT06494891: Recruiting Phase 2 study of Alcohol Use Disorder, sponsored by University of California, Los Angeles.
NCT06494891 is a Phase 2 study of Alcohol Use Disorder that is actively recruiting participants, run by University of California, Los Angeles. The registered enrollment target is 210 participants, below the 327-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (36% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06494891, a Phase 2 study of Alcohol Use Disorder, is actively recruiting participants, sponsored by University of California, Los Angeles.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 210 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this translational study is to understand different reasons why people between the ages of 21 and 65 with alcohol use disorder are motivated to self-administer alcohol. The main questions it aims to answer are: * How does a person's desire for a reward affect their motivation to self-administer alcohol? * How does a person's emotions affect their motivation to self-administer alcohol? * How does a person's cognitive functioning affect their motivation to self-administer alcohol? Participants will be asked to complete questionnaires about their mood, habits, and functioning and will complete an IV alcohol administration that will include pressing a button to receive additional doses of IV alcohol.
Primary Outcome
Scores on the incentive salience factor of the ANA will correlate with craving during the challenge and self-administration during the progressive ratio.
Conditions Studied
Interventions
- DRUG Intravenous Alcohol
Study Locations (1)
California
- University of California, Los Angeles - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 210 participants |
| Start Date | 2024-01-16 |
| Est. Completion | 2027-06-30 |
| Phase | Phase 2 |
What NCT06494891 shows while recruiting
NCT06494891 is an interventional study that assigns participants to a tested intervention. The registered 210 participants enrollment target is mid-sized for trials with a published cap, below the 327-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (36% lower).
The record links to 1 condition, with Alcohol Use Disorder appearing as the primary indexed condition, and to 1 intervention - of which Intravenous Alcohol is the first listed.
NCT06494891 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06494891 about?
NCT06494891 is a clinical study titled "Motivation for IV Alcohol Self-Administration in Humans". The goal of this translational study is to understand different reasons why people between the ages of 21 and 65 with alcohol use disorder are motivated to self-administer alcohol. The main questions it aims to answer are: * How does a person's desire for a reward affect their motivation to self-ad...
What is the current status of trial NCT06494891?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 210 participants. The study started on 2024-01-16. Estimated completion is 2027-06-30.
What conditions does trial NCT06494891 study?
This clinical trial studies the following conditions: Alcohol Use Disorder.
What interventions are being tested in trial NCT06494891?
The interventions under investigation include: Intravenous Alcohol (DRUG).
Who is sponsoring clinical trial NCT06494891?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06494891 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alcohol Use Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06494891's enrollment target sits among peer trials
210 42nd of 184 higher than 143 of 184 other Alcohol Use Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alcohol Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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