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NCT03827460 · ClinicalTrials.gov registry record · Phase 1
Sex Differences in the Response to Abstinence From Alcohol.
A Phase 1 study of Alcohol Use Disorder, sponsored by Indiana University.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 160
- Enrollment target
- 1
- Study location
NCT03827460: Recruiting Phase 1 study of Alcohol Use Disorder, sponsored by Indiana University.
NCT03827460 is a Phase 1 study of Alcohol Use Disorder that is actively recruiting participants, run by Indiana University. The registered enrollment target is 160 participants, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (51% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03827460, a Phase 1 study of Alcohol Use Disorder, is actively recruiting participants, sponsored by Indiana University.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 160 participants
- Enrollment target
- 1
- Study location
Study Summary
In laboratory animals, repeated cycles of abstinence from and return to alcohol drinking can lead to changes in alcohol intake. In a study of the effect of abstinence on drinking in humans, the investigators found evidence that abstinence affects drinking differently in women compared to men. In the present study, the investigators propose to study how men and women respond to abstinence, and whether this information can be used to improve intervention and prevention strategies.
Primary Outcome
The effect of 2 weeks abstinence on intravenous alcohol intake will be compared in men and women.
Conditions Studied
Interventions
- BEHAVIORAL Abstinence from alcohol
- BEHAVIORAL Usual drinking
- DRUG Intravenous Alcohol
Study Locations (1)
Indiana
- University Hospital - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 160 participants |
| Start Date | 2019-04-10 |
| Est. Completion | 2026-08-31 |
| Phase | Phase 1 |
What NCT03827460 shows while recruiting
NCT03827460 is an interventional study that assigns participants to a tested intervention. The registered 160 participants enrollment target is mid-sized for trials with a published cap, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (51% lower).
The record links to 1 condition, with Alcohol Use Disorder appearing as the primary indexed condition, and to 3 interventions - of which Abstinence from alcohol is the first listed.
NCT03827460 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT03827460 about?
NCT03827460 is a clinical study titled "Sex Differences in the Response to Abstinence From Alcohol.". In laboratory animals, repeated cycles of abstinence from and return to alcohol drinking can lead to changes in alcohol intake. In a study of the effect of abstinence on drinking in humans, the investigators found evidence that abstinence affects drinking differently in women compared to men. In the...
What is the current status of trial NCT03827460?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 160 participants. The study started on 2019-04-10. Estimated completion is 2026-08-31.
What conditions does trial NCT03827460 study?
This clinical trial studies the following conditions: Alcohol Use Disorder.
What interventions are being tested in trial NCT03827460?
The interventions under investigation include: Abstinence from alcohol (BEHAVIORAL), Usual drinking (BEHAVIORAL), Intravenous Alcohol (DRUG).
Who is sponsoring clinical trial NCT03827460?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03827460 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alcohol Use Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03827460's enrollment target sits among peer trials
160 58th of 184 higher than 125 of 184 other Alcohol Use Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alcohol Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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