VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is PTSD, with 28 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,668 total, page 4 of 34

RECRUITING NA

The Prostate Cancer, Genetic Risk, and Equitable Screening Study (ProGRESS)

NCT05926102

RECRUITING NA

Veteran Social Support for Enhancing Use of Smoking Cessation Treatment

NCT05868421

RECRUITING NA

High Intensity Interval Training (HIIT) to Reduce Frailty and Enhance Resilience in Older Veterans

NCT05625204

RECRUITING Phase 2

Ca-Mg Butyrate in GWI

NCT05367245

RECRUITING NA

Randomized Clinical Trial of Re-Evaluating Suicidal Thoughts in Veterans

NCT05884476

RECRUITING NA

Quantifying Bone and Skin Movement in the Residual Limb of Individuals With Transtibial Amputation Using Dynamic Stereo X-Ray

NCT05287646

RECRUITING NA

The Effect of a Technology-Mediated Integrated Walking and Tai Chi Intervention on Physical Function in Veterans With COPD and Chronic Musculoskeletal Pain

NCT05701982

RECRUITING NA

Dialectical Behavior Therapy for Justice-Involved Veterans

NCT05974553

RECRUITING NA

Aging Well Through Interactions and Scientific Education - Action Plan (AgeWISE-AP)

NCT06006962

RECRUITING NA

Biomarkers of Reaction To HIIT Exercise

NCT06059872

RECRUITING NA

Pilot Study of Neurofeedback for Photosensitivity in Mild Traumatic Brain Injury

NCT06109909

RECRUITING Phase 1

Novel Cellular Therapy for the Treatment of Pain Associated With Chronic Pancreatitis

NCT05925036

RECRUITING Phase 2

Pimavanserin for Insomnia in Veterans With PTSD

NCT05441280

RECRUITING Phase 2

Randomized Phase II Trial of Targeted Radiation With no Castration for Mcrpc

NCT06084338

RECRUITING NA

Orthotic Treatment of Diabetic Foot Ulcers

NCT05094037

RECRUITING NA

PTSD Treatment for Veterans With Serious Mental Illness to Improve Functional Outcomes

NCT05674617

RECRUITING NA

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

NCT05486572

RECRUITING NA

Somatosensory Tinnitus RCT

NCT05434637

RECRUITING Phase 2

Neuroimaging Correlates and Feasibility of Transcranial Magnetic Stimulation (TMS) to Improve Smoking Cessation Outcomes in Veterans With Comorbid PTSD

NCT05723588

RECRUITING NA

Mechanisms of Gulf War Illness

NCT05972291

RECRUITING NA

Effectiveness of Remote Foot Temperature Monitoring

NCT05728411

RECRUITING NA

Problem-Solving Training for Concussion

NCT05837676

RECRUITING NA

Oxygen-guided Supervised Exercise Therapy

NCT06003855

RECRUITING

Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study

NCT05994482

RECRUITING NA

Group-Based Psychological Treatments Over Video Conference for Older Veterans With Chronic Pain

NCT06004804

RECRUITING

Neurophysiologic Biomarkers for Cognitive Rehabilitation

NCT05945602

RECRUITING NA

MOTIVATE to Improve Outcomes for Older Veterans With Musculoskeletal Pain and Depression

NCT05220202

RECRUITING NA

A Novel Peer-Delivered Recovery-Focused Suicide Prevention Intervention for Veterans With Serious Mental Illness

NCT05537376

RECRUITING NA

Impact of Improving Footwear Options

NCT05601869

RECRUITING NA

Adjunctive Motivational Alcohol Intervention to Prevent IPV

NCT05287711

RECRUITING NA

A Brief Values Intervention to Support Veterans in Early Buprenorphine Treatment

NCT05189223

RECRUITING NA

Impacts of Nicotinamide Riboside on Functional Capacity and Muscle Physiology in Older Veterans

NCT04691986

RECRUITING Phase 4

The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial

NCT05618353

RECRUITING Phase 4

Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits

NCT04419272

RECRUITING NA

Autonomic Effects of Stimulation in SCI

NCT05664646

RECRUITING

Brain Connectivity Changes With Spinal Cord Stimulation and Treatment of Chronic Pain: A Resting State NIRS/EEG Study

NCT05811312

RECRUITING NA

Improving Prosthetic Provision in Rural Communities: Limb Scanning With Caregiver Assistance

NCT05884203

RECRUITING NA

Home-Based Exercise Tele-Rehabilitation After COVID-19

NCT05425264

RECRUITING Phase 2

Proof of Concept Trial of Cannabis Derivatives in Neuropathic Pain

NCT05351801

RECRUITING NA

Treatments in Women Veterans With Insomnia and PTSD

NCT05683132

RECRUITING NA

Non-Inferiority Trial of TrIGR for PTSD

NCT05789329

RECRUITING NA

Brief Behavioral Treatment for Insomnia in Veterans With Posttraumatic Stress Disorder

NCT05780177

RECRUITING Phase 2

Repetitive Transcranial Magnetic Stimulation, a Form of Non-invasive Brain Stimulation, as a Possible Treatment for Post-stroke Fatigue.

NCT05584124

RECRUITING Phase 4

Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

NCT02915198

RECRUITING NA

Incremental Hemodialysis for Veterans in the First Year of Dialysis (IncHVets)

NCT05465044

RECRUITING NA

Expanding Exercise Programming for Veterans Through Telehealth

NCT05666167

RECRUITING Phase 2

Thyroid Hormone for Treatment of Nonalcoholic Steatohepatitis in Veterans

NCT05526144

RECRUITING Phase 2

Virtual Care Strategies to Improve Participation in Cardiac Rehabilitation Among Veterans

NCT05423158

RECRUITING Phase 2

Dynamic Treatment Regiments for Glucocorticoid Tapering

NCT06072768

RECRUITING NA

Integrated CBT to Improve Functioning in Veterans With Anxiety and Substance Use

NCT04871100

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: PTSD (28 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.