Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05974631 · ClinicalTrials.gov registry record · NA
Evaluating Treatments for Suicidal Veterans With PTSD
A NA study of Post Traumatic Stress Disorder (PTSD) and Self-directed Violence, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 125
- Enrollment target
- 4
- Study locations
NCT05974631 is a NA study of Post Traumatic Stress Disorder (PTSD) and Self-directed Violence that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 125 participants, above the 106-participant average among 13 other Post Traumatic Stress Disorder (PTSD) trials with a reported enrollment target (18% higher). The trial reports 4 study locations across 4 states.
The verdict
NCT05974631, a NA study of Post Traumatic Stress Disorder (PTSD) and Self-directed Violence, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 125 participants
- Enrollment target
- 4
- Study locations
Study Summary
Posttraumatic Stress Disorder (PTSD) is a significant driver of suicide risk among Veterans, but there is a critical knowledge gap about how to treat PTSD among people at elevated risk for suicide. Although evidence-based treatments for PTSD reduce suicide risk, Veterans at high risk for suicidal behavior rarely receive these potentially life-saving treatments. Prior research suggests that a treatment that combines Dialectical Behavior Therapy (DBT) with the DBT Prolonged Exposure protocol (DBT PE) for PTSD improves both PTSD and suicide-related outcomes. This study will evaluate whether DBT + DBT PE improves these outcomes more than Prolonged Exposure plus suicide risk management, the gold standard VA care for this population. The proposed study will also examine factors that make it easier and harder to implement these treatments in VA settings. The results will help to inform treatment guidelines for this high-priority Veteran population.
Conditions Studied
Interventions
- BEHAVIORAL Dialectical Behavior Therapy
- BEHAVIORAL Dialectical Behavior Therapy Prolonged Exposure protocol
- BEHAVIORAL Prolonged Exposure therapy
- BEHAVIORAL Suicide risk management
Study Locations (4)
Minnesota
- Minneapolis VA Health Care System, Minneapolis, MN - Minneapolis
North Carolina
- Durham VA Medical Center, Durham, NC - Durham
Texas
- South Texas Health Care System, San Antonio, TX - San Antonio
Washington
- VA Puget Sound Health Care System Seattle Division, Seattle, WA - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 125 participants |
| Start Date | 2024-07-08 |
| Est. Completion | 2027-08-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05974631
The ClinicalTrials.gov registry entry for NCT05974631 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 125 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 106-participant average among 13 other Post Traumatic Stress Disorder (PTSD) trials with a reported enrollment target (18% higher). The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Post Traumatic Stress Disorder (PTSD) appearing as the primary indexed condition, and to 4 interventions - of which Dialectical Behavior Therapy is the first listed.
NCT05974631 reports 4 study locations spanning 4 distinct geographic areas - top geographies include Minnesota, North Carolina, Texas.
Frequently Asked Questions
What is clinical trial NCT05974631 about?
NCT05974631 is a clinical study titled "Evaluating Treatments for Suicidal Veterans With PTSD". Posttraumatic Stress Disorder (PTSD) is a significant driver of suicide risk among Veterans, but there is a critical knowledge gap about how to treat PTSD among people at elevated risk for suicide. Although evidence-based treatments for PTSD reduce suicide risk, Veterans at high risk for suicidal be...
What is the current status of trial NCT05974631?
This trial is currently recruiting. It is a NA study. The enrollment target is 125 participants. The study started on 2024-07-08. Estimated completion is 2027-08-31.
What conditions does trial NCT05974631 study?
This clinical trial studies the following conditions: Post Traumatic Stress Disorder (PTSD), Self-directed Violence.
What interventions are being tested in trial NCT05974631?
The interventions under investigation include: Dialectical Behavior Therapy (BEHAVIORAL), Dialectical Behavior Therapy Prolonged Exposure protocol (BEHAVIORAL), Prolonged Exposure therapy (BEHAVIORAL), Suicide risk management (BEHAVIORAL).
Who is sponsoring clinical trial NCT05974631?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05974631 being conducted?
This trial has 4 study locations across Minnesota, North Carolina, Texas, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Post Traumatic Stress Disorder (PTSD)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Neuromodulation + Prolonged Exposure Therapy: Evaluation of a Technology-Enhanced, Integrated Treatment for Pain and PTSD
RECRUITING · NA
-
Targeted Accelerated TMS for Post-Traumatic Stress Disorder
RECRUITING · NA
-
Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans
RECRUITING · NA
-
NightWare and Cardiovascular Health in Veterans With PTSD
RECRUITING · NA
-
Shared Decision Making in PTSD Treatment
RECRUITING · NA
-
Occupational Therapy Driving Intervention for Returning Combat Veterans.
COMPLETED · NA
Explore more on PlainTrial
Post Traumatic Stress Disorder (PTSD)
All registered trials for this condition
Self-directed Violence
All registered trials for this condition
Minnesota
All trials with a study site in Minnesota
Recruiting now
Find trials open to new participants near you
Rankings
Top sponsors, conditions, and phases
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.