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NCT05974631 · ClinicalTrials.gov registry record · NA
Evaluating Treatments for Suicidal Veterans With PTSD
A NA study of Posttraumatic Stress Disorder (PTSD) and Self-directed Violence, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 125
- Enrollment target
- 4
- Study locations
NCT05974631: Recruiting NA study of Posttraumatic Stress Disorder (PTSD) and Self-directed Violence, sponsored by VA Office of Research and Development.
NCT05974631 is a NA study of Posttraumatic Stress Disorder (PTSD) and Self-directed Violence that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 125 participants, above the 108-participant average among 31 other Posttraumatic Stress Disorder (PTSD) trials with a reported enrollment target (16% higher). The trial reports 4 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05974631, a NA study of Posttraumatic Stress Disorder (PTSD) and Self-directed Violence, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 125 participants
- Enrollment target
- 4
- Study locations
Study Summary
Posttraumatic Stress Disorder (PTSD) is a significant driver of suicide risk among Veterans, but there is a critical knowledge gap about how to treat PTSD among people at elevated risk for suicide. Although evidence-based treatments for PTSD reduce suicide risk, Veterans at high risk for suicidal behavior rarely receive these potentially life-saving treatments. Prior research suggests that a treatment that combines Dialectical Behavior Therapy (DBT) with the DBT Prolonged Exposure protocol (DBT PE) for PTSD improves both PTSD and suicide-related outcomes. This study will evaluate whether DBT + DBT PE improves these outcomes more than Prolonged Exposure plus suicide risk management, the gold standard VA care for this population. The proposed study will also examine factors that make it easier and harder to implement these treatments in VA settings. The results will help to inform treatment guidelines for this high-priority Veteran population.
Primary Outcome
Number of self-directed violence episodes
Conditions Studied
Interventions
- BEHAVIORAL Dialectical Behavior Therapy
- BEHAVIORAL Dialectical Behavior Therapy Prolonged Exposure protocol
- BEHAVIORAL Prolonged Exposure therapy
- BEHAVIORAL Suicide risk management
Study Locations (4)
Minnesota
- Minneapolis VA Health Care System, Minneapolis, MN - Minneapolis
North Carolina
- Durham VA Medical Center, Durham, NC - Durham
Texas
- South Texas Health Care System, San Antonio, TX - San Antonio
Washington
- VA Puget Sound Health Care System Seattle Division, Seattle, WA - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 125 participants |
| Start Date | 2024-07-08 |
| Est. Completion | 2027-08-31 |
| Phase | NA |
What NCT05974631 shows while recruiting
NCT05974631 is an interventional study that assigns participants to a tested intervention. The registered 125 participants enrollment target is mid-sized for trials with a published cap, above the 108-participant average among 31 other Posttraumatic Stress Disorder (PTSD) trials with a reported enrollment target (16% higher).
The record links to 2 conditions, with Posttraumatic Stress Disorder (PTSD) appearing as the primary indexed condition, and to 4 interventions - of which Dialectical Behavior Therapy is the first listed.
NCT05974631 reports a single indexed study location in Minnesota, North Carolina, Texas.
Frequently Asked Questions
What is clinical trial NCT05974631 about?
NCT05974631 is a clinical study titled "Evaluating Treatments for Suicidal Veterans With PTSD". Posttraumatic Stress Disorder (PTSD) is a significant driver of suicide risk among Veterans, but there is a critical knowledge gap about how to treat PTSD among people at elevated risk for suicide. Although evidence-based treatments for PTSD reduce suicide risk, Veterans at high risk for suicidal be...
What is the current status of trial NCT05974631?
This trial is currently recruiting. It is a NA study. The enrollment target is 125 participants. The study started on 2024-07-08. Estimated completion is 2027-08-31.
What conditions does trial NCT05974631 study?
This clinical trial studies the following conditions: Posttraumatic Stress Disorder (PTSD), Self-directed Violence.
What interventions are being tested in trial NCT05974631?
The interventions under investigation include: Dialectical Behavior Therapy (BEHAVIORAL), Dialectical Behavior Therapy Prolonged Exposure protocol (BEHAVIORAL), Prolonged Exposure therapy (BEHAVIORAL), Suicide risk management (BEHAVIORAL).
Who is sponsoring clinical trial NCT05974631?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05974631 being conducted?
This trial has 4 study locations across Minnesota, North Carolina, Texas, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Posttraumatic Stress Disorder (PTSD)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05974631's enrollment target sits among peer trials
125 12th of 31 higher than 19 of 31 other Posttraumatic Stress Disorder (PTSD) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Posttraumatic Stress Disorder (PTSD) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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