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NCT06217198 · ClinicalTrials.gov registry record · NA
A Computerized Depression Intervention in Veterans
A NA study of Depression, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 152
- Enrollment target
- 1
- Study location
NCT06217198: Recruiting NA study of Depression, sponsored by VA Office of Research and Development.
NCT06217198 is a NA study of Depression that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 152 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06217198, a NA study of Depression, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 152 participants
- Enrollment target
- 1
- Study location
Study Summary
Depressive symptoms are common among Veterans and associated with significant impairment. Timely intervention has the potential to improve mental health outcomes and restore functioning. Interventions delivered through the internet can be completed remotely at any time, and thus minimize burden on Veterans, however the research examining their utility in Veterans is limited. This proposed project will examine Deprexis, a self-guided internet-delivered intervention, which targets depressive symptoms and associated functional impairments. Interviews will be conducted to gain insight into Veterans' perceptions, needs, and preferences vis-a-vis Deprexis, with results informing a randomized controlled trial. Here an 8-week course of Deprexis will be compared to a treatment-as-usual (TAU) control condition to establish if Deprexis is acceptable and effective for Veterans with mild to moderate depressive symptoms. Veterans engaged in Deprexis are hypothesized to show improvements on measures of functioning and decreases in depressive symptoms compared to the TAU control group. The proposed work has great clinical utility, as it could provide a readily accessible, high-quality intervention for the many Veterans suffering from depressive symptoms, with the potential to improve functioning and long-term outcomes.
Primary Outcome
The Quick Inventory of Depressive Symptomatology (Self-Report; QIDS-SR-16) is a 16-item self-report measure of depressive symptom severity. This brief measure assesses the 9 DSM-IV symptom criterion domains for depression and has been shown to be highly reliable, internally consistent and sensitive to symptom change. QIDS-SR-16 scores range from 0 to 27, with higher scores indicating more severe depressive symptoms.
Conditions Studied
Interventions
- BEHAVIORAL Deprexis
Study Locations (1)
Texas
- Central Texas Veterans Health Care System Waco VA Medical Center, Waco, TX - Waco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 152 participants |
| Start Date | 2024-05-01 |
| Est. Completion | 2029-04-30 |
| Phase | NA |
What NCT06217198 shows while recruiting
NCT06217198 is an interventional study that assigns participants to a tested intervention. The registered 152 participants enrollment target is mid-sized for trials with a published cap, below the 786-participant average among 679 other Depression trials with a reported enrollment target (81% lower).
The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 1 intervention - of which Deprexis is the first listed.
NCT06217198 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT06217198 about?
NCT06217198 is a clinical study titled "A Computerized Depression Intervention in Veterans". Depressive symptoms are common among Veterans and associated with significant impairment. Timely intervention has the potential to improve mental health outcomes and restore functioning. Interventions delivered through the internet can be completed remotely at any time, and thus minimize burden on V...
What is the current status of trial NCT06217198?
This trial is currently recruiting. It is a NA study. The enrollment target is 152 participants. The study started on 2024-05-01. Estimated completion is 2029-04-30.
What conditions does trial NCT06217198 study?
This clinical trial studies the following conditions: Depression.
What interventions are being tested in trial NCT06217198?
The interventions under investigation include: Deprexis (BEHAVIORAL).
Who is sponsoring clinical trial NCT06217198?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06217198 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06217198's enrollment target sits among peer trials
152 248th of 679 higher than 432 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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