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NCT06172621 · ClinicalTrials.gov registry record · NA

Spinal Cord Associative Plasticity for ALS

A NA study of Amyotrophic Lateral Sclerosis, sponsored by VA Office of Research and Development.

Recruiting
Registry status
NA
Development phase
32
Enrollment target
1
Study location

NCT06172621 is a NA study of Amyotrophic Lateral Sclerosis that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 32 participants, below the 898-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06172621, a NA study of Amyotrophic Lateral Sclerosis, is actively recruiting participants, sponsored by VA Office of Research and Development.

RECRUITING
Registry status
NA
Development phase
32 participants
Enrollment target
1
Study location

Study Summary

Veterans are at higher risk than non-Veterans of falling ill with amyotrophic lateral sclerosis (ALS). The investigators have shown that synchronized stimulation over the brain and cervical spinal cord can temporarily strengthen weakened nerve circuits between the brain and hand muscles in people with ALS. The current proposal will take the next step of individualizing this intervention, then applying it repetitively in an attempt to achieve direct clinical benefit on hand strength and function. Following an initial 2-3 month period of optimizing the intervention for each individual, the investigators will compare the effects of two-week programs of paired brain-spinal stimulation with or without hand exercises.

Interventions

  • PROCEDURE Spinal Cord Associative Plasticity (SCAP)
  • PROCEDURE Upper extremity task-oriented exercise

Study Locations (1)

New York

  • James J. Peters VA Medical Center, Bronx, NY - The Bronx

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2024-04-01
Est. Completion 2028-02-29
Phase NA

Sponsor

VA Office of Research and Development

1,668 total trials

What the Registry Record Tells You About NCT06172621

The ClinicalTrials.gov registry entry for NCT06172621 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 898-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (96% lower). The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Amyotrophic Lateral Sclerosis appearing as the primary indexed condition, and to 2 interventions - of which Spinal Cord Associative Plasticity (SCAP) is the first listed.

NCT06172621 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT06172621 about?

NCT06172621 is a clinical study titled "Spinal Cord Associative Plasticity for ALS". Veterans are at higher risk than non-Veterans of falling ill with amyotrophic lateral sclerosis (ALS). The investigators have shown that synchronized stimulation over the brain and cervical spinal cord can temporarily strengthen weakened nerve circuits between the brain and hand muscles in people w...

What is the current status of trial NCT06172621?

This trial is currently recruiting. It is a NA study. The enrollment target is 32 participants. The study started on 2024-04-01. Estimated completion is 2028-02-29.

What conditions does trial NCT06172621 study?

This clinical trial studies the following conditions: Amyotrophic Lateral Sclerosis.

What interventions are being tested in trial NCT06172621?

The interventions under investigation include: Spinal Cord Associative Plasticity (SCAP) (PROCEDURE), Upper extremity task-oriented exercise (PROCEDURE).

Who is sponsoring clinical trial NCT06172621?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06172621 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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