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NCT05932069 · ClinicalTrials.gov registry record · NA
Active AMD Study to Improve Function in Veterans
A NA study of Age-related Macular Degeneration (AMD), sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 70
- Enrollment target
- 1
- Study location
NCT05932069: Recruiting NA study of Age-related Macular Degeneration (AMD), sponsored by VA Office of Research and Development.
NCT05932069 is a NA study of Age-related Macular Degeneration (AMD) that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 70 participants, below the 101,912-participant average among 7 other Age-related Macular Degeneration (AMD) trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05932069, a NA study of Age-related Macular Degeneration (AMD), is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
Age Related Macular Degeneration (AMD) is the leading cause of vision loss among Veterans aged 50 years and older. AMD also adversely affects mortality, physical and cognitive functioning, and activities of daily living. These debilitations negatively impact quality of life for US Veterans. Unfortunately, there are no cures and few treatments. With the increase in the aging Veteran population and the increasing prevalence of AMD, it is imperative to identify and implement strategies to limit the functional burden of AMD. To address this growing challenge, the investigators propose to test the impact of a proven exercise intervention, stationary bicycling (spinning), on visual and non-visual negative health outcomes in AMD. The work in several retinal degeneration mouse models shows that aerobic exercise significantly preserves retinal morphology and function and visual acuity. Even more exciting, the investigators' preliminary work with older Veterans with and without AMD suggests that spin cycling modestly but significantly benefits visual acuity in aged Veterans. Based on this work, the investigators propose to implement a 6-month synchronous, online group spin cycling program for Veterans with AMD, evaluating effects on physical, cognitive, and visual outcomes.
Primary Outcome
1.Contrast Sensitivity (CS) will be determined using the CSV1000E Contrast Chart. This test provides for four rows ofsine-wave gratings. Subjects will view the chart from a distance of 2.5m. Subjects will view the chart monocularly while wearing their normal correction. CS thresholds will be assessed for both eyes individually.
Conditions Studied
Interventions
- BEHAVIORAL SPIN
- BEHAVIORAL Non-aerobic, stretching/balance intervention Control
Study Locations (1)
Georgia
- Atlanta VA Medical and Rehab Center, Decatur, GA - Decatur
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2024-03-01 |
| Est. Completion | 2028-08-31 |
| Phase | NA |
What NCT05932069 shows while recruiting
NCT05932069 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 101,912-participant average among 7 other Age-related Macular Degeneration (AMD) trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Age-related Macular Degeneration (AMD) appearing as the primary indexed condition, and to 2 interventions - of which SPIN is the first listed.
NCT05932069 reports a single indexed study location in Georgia.
Frequently Asked Questions
What is clinical trial NCT05932069 about?
NCT05932069 is a clinical study titled "Active AMD Study to Improve Function in Veterans". Age Related Macular Degeneration (AMD) is the leading cause of vision loss among Veterans aged 50 years and older. AMD also adversely affects mortality, physical and cognitive functioning, and activities of daily living. These debilitations negatively impact quality of life for US Veterans. Unfortun...
What is the current status of trial NCT05932069?
This trial is currently recruiting. It is a NA study. The enrollment target is 70 participants. The study started on 2024-03-01. Estimated completion is 2028-08-31.
What conditions does trial NCT05932069 study?
This clinical trial studies the following conditions: Age-related Macular Degeneration (AMD).
What interventions are being tested in trial NCT05932069?
The interventions under investigation include: SPIN (BEHAVIORAL), Non-aerobic, stretching/balance intervention Control (BEHAVIORAL).
Who is sponsoring clinical trial NCT05932069?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05932069 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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