Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06068491 · ClinicalTrials.gov registry record · NA
Veteran-Centered Care for Advanced Liver Disease (Vet-CALD)
A NA study of Liver Diseases, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 450
- Enrollment target
- 8
- Study locations
NCT06068491: Recruiting NA study of Liver Diseases, sponsored by VA Office of Research and Development.
NCT06068491 is a NA study of Liver Diseases that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 450 participants, below the 61,145-participant average among 33 other Liver Diseases trials with a reported enrollment target (99% lower). The trial reports 8 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06068491, a NA study of Liver Diseases, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 450 participants
- Enrollment target
- 8
- Study locations
Study Summary
Advanced liver disease is a serious illness that disproportionately affects Veterans, many of whom hope for curative liver transplantation. However, too few receive a transplant and most continue to suffer from increasing symptoms and hospitalizations. The proposed project uses a whole person, Veteran-centered approach that identifies Veterans with advanced liver disease using a population-based health management system and integrates curative and early supportive care using a telemedicine-based nurse care counselor to (1) discuss patient's understanding of illness severity and prognosis, (2) identify priorities and care preferences and (3) align curative and supportive care options to achieve patient priorities. Study outcomes include changes in (1) rates of consideration for liver transplantation, and (2) completion of serious illness discussions. Findings will inform adaptations to the intervention and facilitators for its dissemination.
Primary Outcome
Consideration of Liver Transplantation will be measured dichotomously by assigning a value of 1 if the patient's EHR includes at least one clinician note that documents consideration of liver transplantation as a potential treatment option for the patient within 6 months and 12 months of enrollment, and a value of 0 otherwise.
Conditions Studied
Interventions
- OTHER Vet-CALD
Study Locations (8)
California
- VA Long Beach Healthcare System, Long Beach, CA - Long Beach
- VA Palo Alto Health Care System, Palo Alto, CA - Palo Alto
- VA Greater Los Angeles Healthcare System, West Los Angeles, CA - West Los Angeles
Texas
- VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX - Dallas
- Michael E. DeBakey VA Medical Center, Houston, TX - Houston
Arkansas
- Central Arkansas Veterans Healthcare System , Little Rock, AR - Little Rock
Connecticut
- VA Connecticut Healthcare System West Haven Campus, West Haven, CT - West Haven
Florida
- Miami VA Healthcare System, Miami, FL - Miami
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 450 participants |
| Start Date | 2024-10-01 |
| Est. Completion | 2027-09-30 |
| Phase | NA |
What NCT06068491 shows while recruiting
NCT06068491 is an interventional study that assigns participants to a tested intervention. The registered 450 participants enrollment target is mid-sized for trials with a published cap, below the 61,145-participant average among 33 other Liver Diseases trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Liver Diseases appearing as the primary indexed condition, and to 1 intervention - of which Vet-CALD is the first listed.
NCT06068491 lists 8 locations in 5 states (California, Texas, Arkansas).
Frequently Asked Questions
What is clinical trial NCT06068491 about?
NCT06068491 is a clinical study titled "Veteran-Centered Care for Advanced Liver Disease (Vet-CALD)". Advanced liver disease is a serious illness that disproportionately affects Veterans, many of whom hope for curative liver transplantation. However, too few receive a transplant and most continue to suffer from increasing symptoms and hospitalizations. The proposed project uses a whole person, Veter...
What is the current status of trial NCT06068491?
This trial is currently recruiting. It is a NA study. The enrollment target is 450 participants. The study started on 2024-10-01. Estimated completion is 2027-09-30.
What conditions does trial NCT06068491 study?
This clinical trial studies the following conditions: Liver Diseases.
What interventions are being tested in trial NCT06068491?
The interventions under investigation include: Vet-CALD (OTHER).
Who is sponsoring clinical trial NCT06068491?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06068491 being conducted?
This trial has 8 study locations across Arkansas, California, Connecticut, Florida, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Liver Diseases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06068491's enrollment target sits among peer trials
450 11th of 33 higher than 23 of 33 other Liver Diseases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Liver Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Enhancing Alcohol Treatment Engagement in Associated Liver Disease (ALD) Patients
RECRUITING · NA
-
Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial
RECRUITING · NA
-
A Trial of Post-Discharge Transitional Care for Patients With Chronic Liver Disease
RECRUITING · NA
-
Safety and Efficacy of Endoscopic Ultrasound-Guided Portal Pressure Gradient Measurement
RECRUITING · NA
-
Liver Cancer Prevention Randomized Control Trial
ACTIVE NOT RECRUITING · NA
-
Implementation of a Digital Clinic for Alcohol-associated Liver Disease and Alcohol Use Disorder (DALC)
ACTIVE NOT RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00515060 · 450 participants
Psychophysical Studies of Cancer Therapy Pain
- NCT01257269 · 450 participants
Genotype and Phenotype Correlation in Hereditary Thrombotic Thrombocytopenic Purpura (Upshaw-Schulman Syndrome)
- NCT03047161 · 450 participants
Electrophysiology of Fetal Arrhythmia
- NCT03269630 · 450 participants
New Orleans Pulmonary Hypertension Biobank
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI