University of Texas Southwestern Medical Center

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of Texas Southwestern Medical Center sits in the top decile of US sponsors by registered trial count (#39 of 15,742 sponsors by registered trial count).

837 total trials 162 currently recruiting 503 completed early-phase tilt top decile by trial count

University of Texas Southwestern Medical Center: 837 sponsored US clinical trials, 162 recruiting.

University of Texas Southwestern Medical Center sponsors 837 registered US clinical trials on ClinicalTrials.gov, 162 of them currently recruiting, and 503 completed. 126 of these trials are in Phase 3-4 (later-stage) and 228 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hypertension, with 9 trials.

Top-decile sponsor footprint

University of Texas Southwestern Medical Center ranks in the top decile of sponsors by registered trial count (#39 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 46/100

503 of 608 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (82.7%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

837 total, page 3 of 17

RECRUITING NA

Effectiveness of Repositioning and Cranial Remolding in Infants With Cranial Deformation

NCT05917678

RECRUITING NA

Bladder Cancer Screening Trial

NCT05646485

RECRUITING Phase 4

Safety, Efficacy, and Pharmacokinetics of Tafamidis in Patients With Transthyretin-mediated Amyloidosis Post Orthotopic Heart Transplantation

NCT05489523

RECRUITING Phase 2

Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History

NCT05446584

RECRUITING Phase 1

VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors

NCT04796012

RECRUITING NA

Multicomponent Intervention Study- Blood Donors With High Cholesterol

NCT05693701

RECRUITING NA

Heat Waves and the Elderly - Cooling Modalities

NCT05484739

RECRUITING

Outcomes of Focal Ablation for Prostate Cancer

NCT05478694

RECRUITING

Patients With and Without Phonotrauma

NCT05625191

RECRUITING Phase 2

Neoadjuvant Lenvatinib and Pembrolizumab for IVC Tumor Thrombus

NCT05319015

RECRUITING

Laryngeal Cryotherapy for Refractory Neurogenic Cough

NCT05665244

RECRUITING

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

NCT05489549

RECRUITING Phase 3

Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)

NCT05358535

RECRUITING NA

Impact of Dietary Phosphate Excess on Exercise Capacity and Visceral Adiposity

NCT05147909

RECRUITING NA

Assessing the Efficacy of Targeted Home Visits in the Management of Chronic Conditions

NCT05168605

RECRUITING

Cancer Clinical Trials Financial Reimbursement Program

NCT05402033

RECRUITING NA

Preventing Cognitive Decline by Reducing BP Target Trial

NCT05106036

RECRUITING

South Asians and Coronary Plaque Registry

NCT05367297

RECRUITING

Brain Metabolism Observed at 7 Tesla

NCT05085704

RECRUITING Phase 1

CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast Cancer

NCT05029999

RECRUITING Phase 4

CLOZAPINE Response in Biotype-1

NCT04580134

RECRUITING NA

Motor Network Physiology

NCT04957095

RECRUITING NA

Effects of Obesity in the Aged

NCT05028309

RECRUITING Phase 3

Gemcitabine Versus Water Irrigation in Upper Tract Urothelial Carcinoma

NCT04865939

RECRUITING Phase 4

Markers of Osteoporosis in Cystic Fibrosis

NCT03921060

RECRUITING Early Phase 1

Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)

NCT04838678

RECRUITING Phase 1

Ultra-fractionated Radiotherapy for Rectal Cancer

NCT04677413

RECRUITING

Non-Invasive Testing to Evaluate Wound Healing in Diabetes

NCT04232631

RECRUITING Phase 2

Single Cell Immune and Non-immune Correlates of Response to Neoadjuvant Abemaciclib

NCT04614194

RECRUITING Phase 4

POCUS: Hemostatic Potential and Joint Health in Patients With Severe Hemophilia A on Novel Replacement Therapies

NCT04690322

RECRUITING

The Modulatory Effect of Female Sex Hormones on Spinal Neuroplasticity

NCT06656819

RECRUITING NA

Hyperinflation Respiratory Therapies in Cardiac Surgery Patients

NCT04164173

RECRUITING Phase 2

Peri-Operative Immune Checkpoint Inhibition and Cryoablation in Women With Triple-negative Breast Cancer

NCT03546686

RECRUITING NA

An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy

NCT04623502

RECRUITING Early Phase 1

Pharmacological Modulation of Brain Oscillations in Memory Processing

NCT05594017

RECRUITING NA

Effect of Transcutaneous Electrical Nerve Stimulation on Post-stroke Patients

NCT06541015

RECRUITING NA

Cerebellar tDCS in Children With Autism Spectrum Disorder

NCT04446442

RECRUITING

Metabolic Characteristics of Brain Tumors Using Hyperpolarized Carbon-13 Magnetic Resonance Spectroscopic Imaging (MRSI)

NCT03067467

RECRUITING NA

Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial)

NCT03906435

RECRUITING

Facilitating Diagnostics and Prognostics of Parkinsonian Syndromes Using Neuroimaging

NCT03872102

RECRUITING Phase 3

Trial of Curcumin to Prevent Progression of Low-risk Prostate Cancer Under Active Surveillance

NCT03769766

RECRUITING NA

Multimodal Monitoring of Cerebral Autoregulation After Pediatric Brain Injury

NCT04242602

RECRUITING

Identification of Metabolic Phenotypes Associated With Melanoma Metastasis

NCT06400550

RECRUITING

Dystonia Genotype-Phenotype Correlation

NCT03428009

RECRUITING Phase 1

Neurocognitive Decline in Patients With Brain Metastases

NCT03508752

RECRUITING

Resilience in Adolescent Development

NCT03458936

RECRUITING

Dallas 2K: A Natural History Study of Depression

NCT02919280

RECRUITING

Multiple System Atrophy Multidisciplinary Clinic

NCT03811808

RECRUITING

Establishing Normative Data for Pupillometer Assessments in Neuro-Intensive Care

NCT02804438

RECRUITING Phase 3

JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer

NCT02468024

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Phase Distribution

PhaseTrial count
Phase 1 106
Phase 2 122
Phase 3 28
Phase 4 98

What is open in the University of Texas Southwestern Medical Center pipeline

162 recruiting of 837 indexed (19% open); 503 completed (60%).

Phase mix: 126 late (III/IV) vs 228 early (I/II) (early-phase heavy).

Top condition: Hypertension (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of Texas Southwestern Medical Center: open-pipeline peers nationwide

Peers matched on 837 registered trials and 19% open enrollment, not the therapeutic-area sidebar.

University of Texas Southwestern Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 14%16%18%20%22% Total trials Recruiting share University of Texas Southwestern Medical CenterUniversity of UtahUniversity of ChicagoIndiana UniversityDana-Farber Cancer InstituteCalifornia Polytechnic State University-San Luis ObispoPhoenix Children's HospitalAnn & Robert H Lurie Children's Hospital of ChicagoVanderbilt University Medical Center
University of Texas Southwestern Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of Texas Southwestern Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 837 trials (± recruiting share)

Sponsors near 19% open enrollment (± trial volume)

What to do with this University of Texas Southwestern Medical Center page

837 registered trials is a research-attention snapshot, not an endorsement of University of Texas Southwestern Medical Center or any single study.

  • 162 of University of Texas Southwestern Medical Center's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Hypertension is the condition University of Texas Southwestern Medical Center studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Hypertension trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

University of Texas Southwestern Medical Center pipeline card: 837 registered trials from official public datasets.Report a data error.