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NCT06656819 · ClinicalTrials.gov registry record

The Modulatory Effect of Female Sex Hormones on Spinal Neuroplasticity

A clinical trial of Healthy, sponsored by University of Texas Southwestern Medical Center.

Recruiting
Registry status
50
Enrollment target
1
Study location

NCT06656819 is a study of Healthy that is actively recruiting participants, run by University of Texas Southwestern Medical Center. The registered enrollment target is 50 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06656819, a study of Healthy, is actively recruiting participants, sponsored by University of Texas Southwestern Medical Center.

RECRUITING
Registry status
50 participants
Enrollment target
1
Study location

Study Summary

The goal of this project is to test our central hypothesis that the spinal cord neuroplasticity in females will be modulated by the level of estradiol concentration. under aim 1 we will determine the influence of estradiol fluctuations on spinal circuit excitability post afferent (sensory) mediated subthreshold motor priming in young healthy females and males. We will use an established repetitive peripheral nerve electrical stimulation with a stimulation intensity below the motor threshold to prime the spinal motor circuits. under aim 2 we seek to characterize the input output property of spinal circuit excitability after descending drive (motor) mediated priming in young healthy male participants. in aim 3 we will examine the influence of estradiol fluctuations on descending drive mediated motor priming in young healthy females.

Conditions Studied

Interventions

  • DEVICE Magstim Rapid2

Study Locations (1)

Texas

  • University of Texas Southwestern Medical Center - Dallas

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2020-07-01
Est. Completion 2025-12-31

What the Registry Record Tells You About NCT06656819

The ClinicalTrials.gov registry entry for NCT06656819 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (92% lower). The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 1 intervention - of which Magstim Rapid2 is the first listed.

NCT06656819 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT06656819 about?

NCT06656819 is a clinical study titled "The Modulatory Effect of Female Sex Hormones on Spinal Neuroplasticity". The goal of this project is to test our central hypothesis that the spinal cord neuroplasticity in females will be modulated by the level of estradiol concentration. under aim 1 we will determine the influence of estradiol fluctuations on spinal circuit excitability post afferent (sensory) mediated ...

What is the current status of trial NCT06656819?

This trial is currently recruiting. The enrollment target is 50 participants. The study started on 2020-07-01. Estimated completion is 2025-12-31.

What conditions does trial NCT06656819 study?

This clinical trial studies the following conditions: Healthy.

What interventions are being tested in trial NCT06656819?

The interventions under investigation include: Magstim Rapid2 (DEVICE).

Who is sponsoring clinical trial NCT06656819?

This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06656819 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.