University of Chicago
Trial Pipeline
Spiritual Care Intervention in Adult Patients Diagnosed With Acute Leukemia
NCT07405424
Study to Assess the Feasibility of Stopping Prostate Cancer Treatment Early in Elderly Patients
NCT06824818
Geriatric Assessment and Technology Evaluation in Prostate Cancer
NCT06215508
CApivasertib, Venetoclax And Low-intensity chemotheRapY for Adults With ALL/LBL
NCT07294677
Achieving Routine Intervention and Screening for Emotional Health
NCT06887049
Toripalimab in Combination With Standard Treatment for Human Papillomavirus (HPV) Positive Throat Cancer
NCT07290621
Partial Pleurectomy (Surgery) for Unresectable Pleural Mesothelioma
NCT07126509
Prospective Assessments Following Immediate Lymphatic Reconstruction
NCT07227467
SGLT2i in Kidney Stones
NCT07055282
PSMA PET for Surveillance After Focal Therapy
NCT07115914
STOP-UC: De-escalation of Therapy in Patients With Ulcerative Colitis With Histological Remission
NCT06693310
Type 1 Diabetes and Obstructive Sleep Apnea
NCT06915831
Response-Adaptive Treatment in Untreated Locoregional HPV-Negative Head and Neck Cancer
NCT07065630
Oxalate and Citrate in Humans - Response to Citrate
NCT06944223
Investigating Periprosthetic Fracture Cultures in Arthroplasty
NCT06952738
Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCC
NCT06912087
Phase II Study of the Effects of Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Gastric Cancer
NCT04107077
Hypofractionation (Radiation) Trial for Multiple Myeloma
NCT06270888
Investigating Patient Satisfaction With Smart Knee Implants
NCT06968143
The Microbiota Augmentation to Reestablish Commensal Organisms (MARCO) Trial
NCT06871111
Auricular Acupressure in Prehabilitation
NCT06516198
Lenvatinib and Pembrolizumab to Treat Patients With Anal or Rectum Cancer That Has Gotten Worse After Initial Treatment
NCT06669572
FITting Non-invasive Tests in Lynch Syndrome Surveillance
NCT06898996
Tibial IMN Vs. Tibial Micromotion IMN
NCT06976801
Drug Effects on Mood and Behavior - Expectancy
NCT07061886
Mood Effects of Serotonin Agonists: Depression
NCT07017478
A Bionic Breast Project Using Neuroprosthesis to Reduce Chronic Pain After Mastectomy
NCT06382272
Study of Nutrition and Exercise in Adults Hospitalized for Treatment of Acute Lymphoblastic Leukemia (ALL)
NCT06785324
Prostate Cancer Treatment Using Androgen Deprivation Therapy and Focal Prostate Ablation
NCT05790213
Genicular Artery Embolization for Reducing Pain in Medically Refractory Symptomatic Knee Osteoarthritis
NCT06859164
Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults
NCT06395415
New Strategies to Enhance Smoking Cessation
NCT06751927
Work2Prevent Plus: Structural Intervention to Promote HIV Care in Black Sexual Minority Men
NCT06894199
Semaglutide for Metabolic Intervention and Adipose Loss to Treat Atrial Fibrillation
NCT06499857
Does Ethyl Chloride Spray Work?
NCT06651788
Intravesical Bupivacaine on Post-Operative Ureteroscopy Pain
NCT06635889
Recovery Legal Care Clinical Trial
NCT06618794
Development of a Personalized, Psychosocial Intervention for Menopausal Individuals With Elevated Dementia Risk
NCT06965686
Piloting a Culturally Adapted Suicide Prevention for Black Students in Chicago
NCT07125144
Dysbiosis & Long COVID
NCT06825819
AYA OMGYES Sexual Health Study
NCT06868121
A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer
NCT05726292
Oxytocin Pharmacokinetics and Pharmacodynamics
NCT05488457
Pathobiomes in Gut of Critically Ill Patients
NCT06822465
Study to Test the Combination of Fulvestrant With Lu-DOTATATE for Advanced Pancreatic Neuroendocrine Tumors
NCT06663072
Hemodynamic ABI Monitor
NCT06725108
Objective Assessment of Outcomes Following Immediate Lymphatic Reconstruction / LYMPHA
NCT06650592
Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau
NCT06639503
Reducing Disparities in Urinary Control Symptoms for Minority Women
NCT06798311
Immune Status After Being on Call for 24 Hrs
NCT06636318
Hospital Implementation of a Stroke Protocol for Emergency Evaluation and Disposition
NCT06094478
Ivosidenib and Ruxolitinib in Patients With Advanced Myeloproliferative Neoplasms (MPNs) That Have an IDH1 Gene Mutation
NCT06291987
A Study to Investigate LP-118, Ponatinib, Vincristine and Dexamethasone in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL)
NCT06207123
A Novel Intervention for Weight Loss in Young Adults
NCT06230744
Dex +/- Caffeine Sedation in a Post-MRI Recovery in a Pediatric Population
NCT06538584
Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy
NCT06397456
Communication Bridge 3 Study
NCT06191198
J-RISE: Relevant Implementation Strategies to Eliminate the Social and Structural Barriers to HIV Services Among Justice-involved Black Men Who Have Sex With Men and Other Key Populations
NCT06477588
Comprehensive Geriatric Assessment (Tests) for Bladder Cancer Participants Undergoing Radical Cystectomy
NCT06427824
Brain Function Monitoring During Surgery
NCT06619730
Informing Pain Treatment Using Pharmacogenomic Analysis
NCT06511401
TheraT® Vectors (Vaccines) Combined With Chemotherapy to Treat HPV16 Head and Neck Cancers
NCT05108870
Patient Outcome Reporting for Timely Assessments of Life With Post-Traumatic Stress Disorder
NCT06479447
Let's E.A.T.! (Eating With Assistive Technology): An Intervention to Support Children With Feeding Tubes and Tracheostomies
NCT06525818
Dime La VerDAD: Verify, Debunk, and Disseminate
NCT06417762
Kidney Stone Inflammation
NCT06436235
Manipulation of the Gut Microbiome by a Standardized Preoperative Diet to Prevent Colorectal Cancer Recurrence and Metastasis Following Surgery
NCT06349590
Prostate Ablation Registry and Database for Information, Surveillance, and Evaluation (PARADISE)
NCT06705803
Posterior Rectus Sheath Hiatal Augmentation in Paraesophageal Hernia Repair
NCT06551077
Get Fit for Function
NCT06359652
Metabolic Endpoints for Obstructive Sleep Apnea Following Twelfth Cranial Nerve Stimulation
NCT06317701
Changes in Glucose Tolerance in Patients With Cirrhosis Peri-Liver Transplant
NCT06950788
Safety, Tolerability, and Efficacy of Immunomodulation With A Monoclonal Antibody Against CD40L in Combination With Transplanted Islet Cells in Adults With Brittle Type 1 Diabetes Mellitus (T1D)
NCT06305286
Feasibility of a Dog Training Therapy Program in UC Outpatient Youth Receiving Psychiatric Services
NCT05788783
Prevention of Postoperative Atrial Fibrillation (POAF) Using Intra-Pericardial Amiodarone
NCT06063538
Durometer for Measuring Uterine Tone
NCT06284421
Oxygenation in Vascular Lesions of the Colon
NCT06230731
Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues
NCT06171152
Quantitative Assessment of Autologous Fat Transfer
NCT06343831
Using MRI to Identify Areas to Receive Lower Doses of Radiation Treatment in Men With Prostate Cancerdose Mapping to Preserve Quality of Life
NCT06171269
Combining Biomarkers and Electronic Risk Scores to Predict AKI in Hospitalized Patients
NCT05988658
Video Training Supplementation for Patients Discharged on Home Parental Nutrition
NCT06169774
Personalized, Adaptive Treatment for Locally Advanced Head and Neck Cancer
NCT06005324
Biobank Cardiac Surgery
NCT06747806
Percutaneous Nerve Evaluation Trial Time
NCT06226220
Novel Outreach Methods to Increase Enrollment to Early Phase Clinical Trials
NCT05886764
Creation of a Prospective Data Collecting Registry for Genicular Artery Embolization for Arthritis
NCT06781463
Frameless Stereotactic Radiosurgery for Intact Brain Metastases
NCT02747303
Chicago Asthma School-Directed Child-Centered Assessment and Dissemination of Evidence
NCT06320210
PrEP Optimization Among Women to Enhance Retention and Uptake
NCT05626452
Tissue Destruction and Healing in Celiac Disease
NCT05680012
Cardiac Power Output in Cardiogenic Shock Patients
NCT05700617
A Pilot Clinical Evaluation of Astepro® Nasal Spray for Management of Early SARS-CoV-2 Infection
NCT06008860
Effect of Cooling Therapy for Post-Operative Pain in Open Carpal Tunnel Release
NCT05783245
Interactive Computer-adaptive Chronic Kidney Disease Education Program
NCT06364358
Study of Belantamab Mafodotin With Carfilzomib, Pomalidomide, and Dexamethasone in Relapsed Multiple Myeloma
NCT05789303
LH Canine Therapy Study
NCT05840198
MRI Risk Maps for Prostate Cancer Diagnosis Using Targeted Biopsy
NCT05710380
Tocilizumab for Acute Chest Syndrome
NCT05640271
Dosing Study of Radiation Combined With Tislelizumab and Pamiparib in Patients With Previously Treated Head and Neck Cancer
NCT05526924
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 217 |
| Phase 2 | 113 |
| Phase 3 | 4 |
| Phase 4 | 9 |
Therapeutic Areas
What the Pipeline for University of Chicago Shows
According to the ClinicalTrials.gov registry, University of Chicago is linked to 846 US clinical trials across every stage of research activity. Of those, 692 studies are currently recruiting — about 82% of the sponsor's indexed portfolio — and 94 are already marked complete, representing roughly 11% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for University of Chicago reports 13 late-stage studies (Phase 3 and Phase 4 combined) and 330 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for University of Chicago is Prostate Cancer with 11 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.