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NCT03428009 · ClinicalTrials.gov registry record
Dystonia Genotype-Phenotype Correlation
A clinical trial of Dystonia and Dystonia Disorder, sponsored by University of Texas Southwestern Medical Center.
- Recruiting
- Registry status
- 200
- Enrollment target
- 1
- Study location
NCT03428009: Recruiting study of Dystonia and Dystonia Disorder, sponsored by University of Texas Southwestern Medical Center.
NCT03428009 is a study of Dystonia and Dystonia Disorder that is actively recruiting participants, run by University of Texas Southwestern Medical Center. The registered enrollment target is 200 participants, below the 533-participant average among 28 other Dystonia trials with a reported enrollment target (62% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03428009, a study of Dystonia and Dystonia Disorder, is actively recruiting participants, sponsored by University of Texas Southwestern Medical Center.
- RECRUITING
- Registry status
- 200 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to (1) investigate the effect of known dystonia-causing mutations on brain structure and function, to (2) identify structural brain changes that differ between clinical phenotypes of dystonia, and to (3) collect DNA, detailed family history, and clinical phenotypes from patients with idiopathic dystonia with the goal of identifying new dystonia-related genes. Investigators will be recruiting both healthy control subjects and subjects with any form of dystonia. For this study there will be a maximum of two study visit involving a clinical assessment, collection of medical and family history, task training session, an MRI using the learned tasks, and finally a blood draw for genetic analysis. In total, these visits will take 3-5 hours. If the dystonia subjects receive botulinum toxin injections for treatment, the participants and their matched controls will be asked to come for a second visit.
Primary Outcome
Identify structural or functional imaging measures that distinguish (a) dystonia patients from matched controls, (b) between clinically-defined forms of dystonia
Conditions Studied
Interventions
- OTHER Magnetic Resonance Imaging
Study Locations (1)
Texas
- University of Texas Southwestern Medical Center - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2018-03-01 |
| Est. Completion | 2027-09 |
What NCT03428009 shows while recruiting
NCT03428009 is an observational study that tracks outcomes without assigning an intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 533-participant average among 28 other Dystonia trials with a reported enrollment target (62% lower).
The record links to 10 conditions, with Dystonia appearing as the primary indexed condition, and to 1 intervention - of which Magnetic Resonance Imaging is the first listed.
NCT03428009 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT03428009 about?
NCT03428009 is a clinical study titled "Dystonia Genotype-Phenotype Correlation". The purpose of this study is to (1) investigate the effect of known dystonia-causing mutations on brain structure and function, to (2) identify structural brain changes that differ between clinical phenotypes of dystonia, and to (3) collect DNA, detailed family history, and clinical phenotypes from ...
What is the current status of trial NCT03428009?
This trial is currently recruiting. The enrollment target is 200 participants. The study started on 2018-03-01. Estimated completion is 2027-09.
What conditions does trial NCT03428009 study?
This clinical trial studies the following conditions: Dystonia, Dystonia Disorder, Dystonia, Secondary, Dystonia; Idiopathic, Dystonia, Primary.
What interventions are being tested in trial NCT03428009?
The interventions under investigation include: Magnetic Resonance Imaging (OTHER).
Who is sponsoring clinical trial NCT03428009?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03428009 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Dystonia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03428009's enrollment target sits among peer trials
200 7th of 28 higher than 21 of 28 other Dystonia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Dystonia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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