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NCT03428009 · ClinicalTrials.gov registry record

Dystonia Genotype-Phenotype Correlation

A clinical trial of Dystonia and Dystonia Disorder, sponsored by University of Texas Southwestern Medical Center.

Recruiting
Registry status
200
Enrollment target
1
Study location

NCT03428009 is a study of Dystonia and Dystonia Disorder that is actively recruiting participants, run by University of Texas Southwestern Medical Center. The registered enrollment target is 200 participants, below the 533-participant average among 28 other Dystonia trials with a reported enrollment target (62% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03428009, a study of Dystonia and Dystonia Disorder, is actively recruiting participants, sponsored by University of Texas Southwestern Medical Center.

RECRUITING
Registry status
200 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to (1) investigate the effect of known dystonia-causing mutations on brain structure and function, to (2) identify structural brain changes that differ between clinical phenotypes of dystonia, and to (3) collect DNA, detailed family history, and clinical phenotypes from patients with idiopathic dystonia with the goal of identifying new dystonia-related genes. Investigators will be recruiting both healthy control subjects and subjects with any form of dystonia. For this study there will be a maximum of two study visit involving a clinical assessment, collection of medical and family history, task training session, an MRI using the learned tasks, and finally a blood draw for genetic analysis. In total, these visits will take 3-5 hours. If the dystonia subjects receive botulinum toxin injections for treatment, the participants and their matched controls will be asked to come for a second visit.

Interventions

  • OTHER Magnetic Resonance Imaging

Study Locations (1)

Texas

  • University of Texas Southwestern Medical Center - Dallas

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2018-03-01
Est. Completion 2027-09

What the Registry Record Tells You About NCT03428009

The ClinicalTrials.gov registry entry for NCT03428009 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 533-participant average among 28 other Dystonia trials with a reported enrollment target (62% lower). The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.

The record links to 10 conditions, with Dystonia appearing as the primary indexed condition, and to 1 intervention - of which Magnetic Resonance Imaging is the first listed.

NCT03428009 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT03428009 about?

NCT03428009 is a clinical study titled "Dystonia Genotype-Phenotype Correlation". The purpose of this study is to (1) investigate the effect of known dystonia-causing mutations on brain structure and function, to (2) identify structural brain changes that differ between clinical phenotypes of dystonia, and to (3) collect DNA, detailed family history, and clinical phenotypes from ...

What is the current status of trial NCT03428009?

This trial is currently recruiting. The enrollment target is 200 participants. The study started on 2018-03-01. Estimated completion is 2027-09.

What conditions does trial NCT03428009 study?

This clinical trial studies the following conditions: Dystonia, Dystonia Disorder, Dystonia, Secondary, Dystonia; Idiopathic, Dystonia, Primary.

What interventions are being tested in trial NCT03428009?

The interventions under investigation include: Magnetic Resonance Imaging (OTHER).

Who is sponsoring clinical trial NCT03428009?

This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03428009 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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