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NCT05147909 · ClinicalTrials.gov registry record · NA

Impact of Dietary Phosphate Excess on Exercise Capacity and Visceral Adiposity

A NA study of Physical Inactivity and Visceral Obesity, sponsored by University of Texas Southwestern Medical Center.

Recruiting
Registry status
NA
Development phase
124
Enrollment target
1
Study location

NCT05147909: Recruiting NA study of Physical Inactivity and Visceral Obesity, sponsored by University of Texas Southwestern Medical Center.

NCT05147909 is a NA study of Physical Inactivity and Visceral Obesity that is actively recruiting participants, run by University of Texas Southwestern Medical Center. The registered enrollment target is 124 participants, below the 223-participant average among 59 other Physical Inactivity trials with a reported enrollment target (44% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05147909, a NA study of Physical Inactivity and Visceral Obesity, is actively recruiting participants, sponsored by University of Texas Southwestern Medical Center.

RECRUITING
Registry status
NA
Development phase
124 participants
Enrollment target
1
Study location

Study Summary

Studies in mice demonstrated that dietary phosphate (Pi) loading that mimic the level of US adult consumption leads to reduced spontaneous locomotor activity, exercise capacity, and reduced resting metabolic rate when in normal mice by impairing skeletal muscle mitochondrial function and fat oxidation. However, relevance of this findings in humans remains unknown.

Primary Outcome

VO2 (ml of oxygen consumed /min) will be measured using a metabolic cart (Medgraphics) during exercise in a stationary bicycle. Standard breath-by-breath respiratory gases (VO2) will be measured at rest and after 3 minutes of steady state exercise at both 20 and 40 Watts using a cycle ergometer (Lode). Then, the partcipants will be asked to perform exercise to maximal level to obtain peak VO2.

Interventions

  • DIETARY_SUPPLEMENT Sodium Phosphate
  • DIETARY_SUPPLEMENT Sodium Chloride

Study Locations (1)

Texas

  • University of Texas Southwestern - Dallas

Trial Details

FieldValue
Enrollment Target 124 participants
Start Date 2022-09-14
Est. Completion 2028-03-30
Phase NA

What NCT05147909 shows while recruiting

NCT05147909 is an interventional study that assigns participants to a tested intervention. The registered 124 participants enrollment target is mid-sized for trials with a published cap, below the 223-participant average among 59 other Physical Inactivity trials with a reported enrollment target (44% lower).

The record links to 3 conditions, with Physical Inactivity appearing as the primary indexed condition, and to 2 interventions - of which Sodium Phosphate is the first listed.

NCT05147909 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT05147909 about?

NCT05147909 is a clinical study titled "Impact of Dietary Phosphate Excess on Exercise Capacity and Visceral Adiposity". Studies in mice demonstrated that dietary phosphate (Pi) loading that mimic the level of US adult consumption leads to reduced spontaneous locomotor activity, exercise capacity, and reduced resting metabolic rate when in normal mice by impairing skeletal muscle mitochondrial function and fat oxidati...

What is the current status of trial NCT05147909?

This trial is currently recruiting. It is a NA study. The enrollment target is 124 participants. The study started on 2022-09-14. Estimated completion is 2028-03-30.

What conditions does trial NCT05147909 study?

This clinical trial studies the following conditions: Physical Inactivity, Visceral Obesity, Phosphate Overload.

What interventions are being tested in trial NCT05147909?

The interventions under investigation include: Sodium Phosphate (DIETARY_SUPPLEMENT), Sodium Chloride (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT05147909?

This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05147909 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Physical Inactivity

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05147909's enrollment target sits among peer trials

124 28th of 59 higher than 31 of 59 other Physical Inactivity trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Physical Inactivity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05147909, the US trial registry maintained by the National Library of Medicine. NCT05147909 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.