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NCT04690322 · ClinicalTrials.gov registry record · Phase 4

POCUS: Hemostatic Potential and Joint Health in Patients With Severe Hemophilia A on Novel Replacement Therapies

A Phase 4 study of Hemophilia A and Factor VIII, sponsored by University of Texas Southwestern Medical Center.

Recruiting
Registry status
Phase 4
Development phase
28
Enrollment target
1
Study location

NCT04690322 is a Phase 4 study of Hemophilia A and Factor VIII that is actively recruiting participants, run by University of Texas Southwestern Medical Center. The registered enrollment target is 28 participants, below the 91-participant average among 42 other Hemophilia A trials with a reported enrollment target (69% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04690322, a Phase 4 study of Hemophilia A and Factor VIII, is actively recruiting participants, sponsored by University of Texas Southwestern Medical Center.

RECRUITING
Registry status
Phase 4
Development phase
28 participants
Enrollment target
1
Study location

Study Summary

This is a prospective, randomized control trial in which each patient will be randomly assigned to receive either extended half-life factor VIII based replacement therapy or non-FVIII based replacement therapy, which are both standard of care treatment for persons with Hemophilia A.

Conditions Studied

Interventions

  • DRUG Emicizumab
  • DRUG Eloctate
  • DRUG Adynovate

Study Locations (1)

Texas

  • The University of Texas Southwestern Medical Center - Dallas

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2021-04-15
Est. Completion 2027-07
Phase Phase 4

What the Registry Record Tells You About NCT04690322

The ClinicalTrials.gov registry entry for NCT04690322 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 91-participant average among 42 other Hemophilia A trials with a reported enrollment target (69% lower). The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Hemophilia A appearing as the primary indexed condition, and to 3 interventions - of which Emicizumab is the first listed.

NCT04690322 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT04690322 about?

NCT04690322 is a clinical study titled "POCUS: Hemostatic Potential and Joint Health in Patients With Severe Hemophilia A on Novel Replacement Therapies". This is a prospective, randomized control trial in which each patient will be randomly assigned to receive either extended half-life factor VIII based replacement therapy or non-FVIII based replacement therapy, which are both standard of care treatment for persons with Hemophilia A.

What is the current status of trial NCT04690322?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 28 participants. The study started on 2021-04-15. Estimated completion is 2027-07.

What conditions does trial NCT04690322 study?

This clinical trial studies the following conditions: Hemophilia A, Factor VIII.

What interventions are being tested in trial NCT04690322?

The interventions under investigation include: Emicizumab (DRUG), Eloctate (DRUG), Adynovate (DRUG).

Who is sponsoring clinical trial NCT04690322?

This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04690322 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.