University of Texas Southwestern Medical Center

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of Texas Southwestern Medical Center sits in the top decile of US sponsors by registered trial count (#39 of 15,742 sponsors by registered trial count).

837 total trials 162 currently recruiting 503 completed early-phase tilt top decile by trial count

University of Texas Southwestern Medical Center: 837 sponsored US clinical trials, 162 recruiting.

University of Texas Southwestern Medical Center sponsors 837 registered US clinical trials on ClinicalTrials.gov, 162 of them currently recruiting, and 503 completed. 126 of these trials are in Phase 3-4 (later-stage) and 228 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hypertension, with 9 trials.

Top-decile sponsor footprint

University of Texas Southwestern Medical Center ranks in the top decile of sponsors by registered trial count (#39 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 46/100

503 of 608 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (82.7%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

837 total, page 4 of 17

RECRUITING

Genetic and Metabolic Disease in Children

NCT02650622

RECRUITING NA

DExterous Hand Control Through Fascicular Targeting (DEFT) - (Human Subjects)

NCT02994160

RECRUITING

Multiparametric Image Analysis and Correlation With Outcomes in Lung Cancer Screening and Early Stage Lung Cancer

NCT03563976

RECRUITING NA

Metabolic Biomarkers in Thoracic Cancers

NCT02095808

RECRUITING

Registry Study to Evaluate the Clinical Outcome of Cancer Patients and Benign Diseases Treated with Radiation

NCT03617237

RECRUITING NA

Intacs Prescription Inserts for Keratoconus Patients

NCT02138669

RECRUITING Phase 4

Vitamin D Homeostasis in Sarcoidosis

NCT03621553

RECRUITING

Collecting Tissue Samples From Patients With Cancer Undergoing Radiation Therapy and Healthy Participants

NCT00992303

RECRUITING NA

An Investigation of Brain Tumor Metabolism in Patients Undergoing Surgical Resection

NCT01668082

RECRUITING

Cutaneous Lupus Registry

NCT01266915

RECRUITING

Morphea in Adults and Children (MAC) Cohort Study: A Morphea Registry and DNA Repository

NCT01808937

RECRUITING

NARCOMS Registry: A Multiple Sclerosis Registry

NCT01018537

ACTIVE NOT RECRUITING Phase 2

Tirzepatide for Obesity and Meth Use Disorder

NCT06745128

ACTIVE NOT RECRUITING NA

Skin Surface and Intradermal Temperature Responses to Heat Stress

NCT06593067

ACTIVE NOT RECRUITING

Studying the Health of Asians to Advance Knowledge, Treatments, and Interventions for Depression

NCT06002204

ACTIVE NOT RECRUITING NA

Pedi-Cap CO2 Detector for Face-mask Ventilation in the Delivery Room

NCT06258187

ACTIVE NOT RECRUITING Phase 2

Clinical Trial of All-trans-retinoic Acid, Bevacizumab and Atezolizumab in Colorectal Cancer

NCT05999812

ACTIVE NOT RECRUITING Phase 4

DIALYSIS-TIR Study

NCT06042153

ACTIVE NOT RECRUITING Phase 2

Domvanalimab and Zimberelimab in Advanced Liver Cancers

NCT05724563

ACTIVE NOT RECRUITING Phase 3

Tofacitinib in Recurrent GBM Patients

NCT05326464

ACTIVE NOT RECRUITING Phase 2

Personalized Ultra-fractionated Stereotactic Adaptive Radiotherapy for Metastatic Cervical Cancer

NCT05021237

ACTIVE NOT RECRUITING NA

Alcohol Induced de Novo Lipogenesis in Women

NCT04829110

ACTIVE NOT RECRUITING Phase 2

Phase 2 Trial of Afatinib Plus Prednisone for Advanced Squamous NSCLC

NCT04497584

ACTIVE NOT RECRUITING Phase 2

Durvalumab and Stereotactic Radiotherapy for Advanced NSCLC

NCT04786093

ACTIVE NOT RECRUITING

Aging and Disease Course: Contributions to Lifespan Neurobiology of Schizophrenia

NCT04951700

ACTIVE NOT RECRUITING

FUVID Study: Functional Characterization of Children With Chronic Venous Thromboembolic Disease

NCT04583878

ACTIVE NOT RECRUITING Phase 1

HYPORT: A Phase I/II Study of Hypofractionated Post-operative Radiation Therapy for Head and Neck Cancer

NCT04403620

ACTIVE NOT RECRUITING Phase 2

INNATE: Immunotherapy During Neoadjuvant Therapy for Rectal Cancer

NCT04130854

ACTIVE NOT RECRUITING Phase 4

Cladribine Tablets After Treatment With Natalizumab (CLADRINA)

NCT04178005

ACTIVE NOT RECRUITING Phase 1

A Phase I Dose Escalation Study of Single Fraction Pre-operative Partial Breast (S-PBI) for Early Stage Breast Cancer

NCT04040569

ACTIVE NOT RECRUITING NA

Mechanisms of Exercise Intolerance in Heart Failure With Preserved Ejection Fraction

NCT04068844

ACTIVE NOT RECRUITING

Is There a Microbiome Associated With Poor Growth in Preterm Infants?

NCT03761498

ACTIVE NOT RECRUITING

ALTA TIPS: A 5-year Longitudinal Observational Study of Patients Undergoing TIPS Placement

NCT03973372

ACTIVE NOT RECRUITING

Extreme Lipids Repository

NCT04156997

ACTIVE NOT RECRUITING NA

Phase II Multi-center Trial Evaluating 5 Fraction Stereotactic Partial Breast Irradiation Using Gammapod

NCT03581136

ACTIVE NOT RECRUITING Phase 2

Neoadjuvant Her2-targeted Therapy and Immunotherapy With Pembrolizumab [IIT2018-04-MCARTHUR-NEOHP]

NCT03747120

ACTIVE NOT RECRUITING Phase 2

Study of Osimertinib and Stereotactic Ablative Radiation (SABR) in EGFR Mutant NSCLC

NCT03667820

ACTIVE NOT RECRUITING Phase 2

SAbR For Oligometastatic Renal Cell Carcinoma

NCT02956798

ACTIVE NOT RECRUITING Phase 2

Prostate Oncologic Therapy While Ensuring Neurovascular Conservation (POTEN-C)

NCT03525262

ACTIVE NOT RECRUITING Phase 2

Potential Therapeutic Role of Effervescent Calcium-Magnesium Citrate in Chronic Kidney Disease Stage V

NCT03565913

ACTIVE NOT RECRUITING

Acute Kidney Injury Genomics and Biomarkers in TAVR Study

NCT02791880

ACTIVE NOT RECRUITING Phase 1

Phase I Dose Escalation of Single Fraction Adjuvant Stereotactic Body Partial Breast Irradiation Early Stage Breast CA

NCT02685332

ACTIVE NOT RECRUITING NA

Stereotactic Radiosurgery (SRS) Dose-Escalation Study for Brain Metastasis

NCT02645487

ACTIVE NOT RECRUITING Phase 1

Stereotactic Ablative Radiotherapy (SABR) of Pelvis and Prostate Targets For High Risk Prostate Cancer

NCT02353819

ACTIVE NOT RECRUITING Phase 1

Neo-adjuvant SABR for IVC Tumor Thrombus in Newly Diagnosed RCC

NCT02473536

ACTIVE NOT RECRUITING

PET Avidity in Cachexia-Inducing Lung and Gastrointestinal Tumors

NCT03568019

ACTIVE NOT RECRUITING NA

PROSPR Project 1: Identifying and Tracking Personalized CRC Screening Regimens for Patients in Clinical Settings

NCT03705897

ACTIVE NOT RECRUITING Phase 2

Stereotactic Ablative Body Radiation Therapy for Patients With Primary Renal Cancer

NCT02141919

ACTIVE NOT RECRUITING

The Longitudinal CONQUER Study of Rare Neuroimmunologic Disorders

NCT01623076

ACTIVE NOT RECRUITING

Database Registry for Neural Network Biomarkers in Psychosis

NCT01409109

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Phase Distribution

PhaseTrial count
Phase 1 106
Phase 2 122
Phase 3 28
Phase 4 98

What is open in the University of Texas Southwestern Medical Center pipeline

162 recruiting of 837 indexed (19% open); 503 completed (60%).

Phase mix: 126 late (III/IV) vs 228 early (I/II) (early-phase heavy).

Top condition: Hypertension (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of Texas Southwestern Medical Center: open-pipeline peers nationwide

Peers matched on 837 registered trials and 19% open enrollment, not the therapeutic-area sidebar.

University of Texas Southwestern Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 14%16%18%20%22% Total trials Recruiting share University of Texas Southwestern Medical CenterUniversity of UtahUniversity of ChicagoIndiana UniversityDana-Farber Cancer InstituteCalifornia Polytechnic State University-San Luis ObispoPhoenix Children's HospitalAnn & Robert H Lurie Children's Hospital of ChicagoVanderbilt University Medical Center
University of Texas Southwestern Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of Texas Southwestern Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 837 trials (± recruiting share)

Sponsors near 19% open enrollment (± trial volume)

What to do with this University of Texas Southwestern Medical Center page

837 registered trials is a research-attention snapshot, not an endorsement of University of Texas Southwestern Medical Center or any single study.

  • 162 of University of Texas Southwestern Medical Center's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Hypertension is the condition University of Texas Southwestern Medical Center studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Hypertension trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

University of Texas Southwestern Medical Center pipeline card: 837 registered trials from official public datasets.Report a data error.