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ClinicalTrials.gov 275 recruiting now early-phase tilt #4 of 28,963 conditions

Prostate Cancer: early-phase trial registry

275 of 749 indexed Prostate Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #4 of 28,963 conditions by registered trial count.

749 US clinical trials · 275 currently recruiting · #4 of 28,963 conditions by registered trial count

Prostate Cancer: 749 US clinical trials tracked, 275 recruiting.

Prostate Cancer is the subject of 749 registered US clinical trials on ClinicalTrials.gov, 275 of them currently open to new participants. 75 are in Phase 3-4 (later-stage) and 344 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 53 of these trials.

Open enrollment, early-phase tilt

Prostate Cancer has 749 registered US clinical trials, 275 of them open to new participants right now, about 37% of the total.

275
recruiting participants now
37%
of trials open to enrollment
75
in Phase 3-4 (later-stage)
53
top sponsor: Memorial Sloan Kettering Cancer Center

Corpus placement: #4 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Prostate Cancer on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Prostate Cancer recruits in line with its size-band peers.

    275 of 749 indexed trials (36.7%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Prostate Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 53 of 749 trials (7.1%). 283 distinct sponsors appear on at least one study for this condition label.

  3. Typical Prostate Cancer enrolment sits around 82 participants.

    Median target enrolment is 82 among the 736 trials that report a genuine target (sentinel values excluded). 389 of those (52.9%) plan for fewer than 100 participants.

  4. Prostate Cancer research is mostly interventional.

    628 interventional and 121 observational studies make up this index (83.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1156Phase 2188Phase 362Phase 413

Open and recent trials

749 total, page 1 of 15

RECRUITING NA 40,000 participants

Impact of an Electronic Health Record Maintenance Alert on PSA Screening Rates in a 10-Hospital Integrated Health System

Washington University School of Medicine

NCT07109427

RECRUITING 10,000 participants

Profiling of Radiological Factors in Treatment and Outcomes in Prostate Cancer

National Cancer Institute (NCI)

NCT03354416

RECRUITING 9,600 participants

Sample Collection for Ongoing Research and Product Evaluation Study

Natera

NCT07318051

RECRUITING 8,000 participants

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

UMC Utrecht

NCT04075305

RECRUITING NA 6,000 participants

A RAndomizeD Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients

McMaster University

NCT03127631

RECRUITING 5,000 participants

International Registry for Men With Advanced Prostate Cancer (IRONMAN)

Prostate Cancer Clinical Trials Consortium

NCT03151629

RECRUITING NA 5,000 participants

The Prostate Cancer, Genetic Risk, and Equitable Screening Study (ProGRESS)

VA Office of Research and Development

NCT05926102

RECRUITING 3,000 participants

Care of the Prostate Cancer Patient and Prospective Procurement of Prostate Cancer Tissue

National Cancer Institute (NCI)

NCT02594202

RECRUITING 3,000 participants

Prostate Ablation Registry and Database for Information, Surveillance, and Evaluation (PARADISE)

University of Chicago

NCT06705803

RECRUITING 2,000 participants

Precision-Based Genomics in Prostate Cancer

National Cancer Institute (NCI)

NCT04706663

RECRUITING NA 1,800 participants

Prospective Evaluation of Pencil Beam Scanning Proton Therapy for Previously Irradiated Tumors

The New York Proton Center

NCT05313191

RECRUITING 1,750 participants

Collection of Blood From Patients With Cancer

National Cancer Institute (NCI)

NCT00034216

RECRUITING NA 1,750 participants

MATCH-UP: MAking Telehealth-Delivery of Cancer Care at Home Effective and Safe-Upscaled: A Pragmatic Cluster Randomized Trial

Memorial Sloan Kettering Cancer Center

NCT06954337

RECRUITING NA 1,500 participants

Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer

Adam S. Kibel, MD

NCT06398639

RECRUITING 1,500 participants

African Cancer Genome: GMD

Fox Chase Cancer Center

NCT05754658

RECRUITING Phase 3 1,440 participants

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

Merck Sharp & Dohme

NCT06925737

RECRUITING NA 1,306 participants

Fusion or Cognitive Ultrasound-guided Biopsy to Detect Prostate Cancer

Albany Medical College

NCT06517901

RECRUITING 1,100 participants

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

National Cancer Institute (NCI)

NCT01441089

RECRUITING NA 1,020 participants

Video Education With Result Dependent dIsclosure

Dana-Farber Cancer Institute

NCT05225428

RECRUITING 1,000 participants

Performance of Inherited Risk Assessment for Predicting Prostate Cancer From Prostate Biopsy

Endeavor Health

NCT05295407

RECRUITING 1,000 participants

Real World Prostate Cancer Registry

Cincinnati Cancer Advisors

NCT06355336

RECRUITING 1,000 participants

Customized TULSA-PRO Ablation Registry

Profound Medical

NCT05001477

RECRUITING 1,000 participants

Collection of Blood From Patients With Prostate Cancer

National Cancer Institute (NCI)

NCT00923221

RECRUITING 1,000 participants

Prospective Database of Clinical Outcomes Following Cryotherapy for Ablation of Clinically Localized Prostate Cancer

NYU Langone Health

NCT07184957

RECRUITING NA 1,000 participants

Improving Nutrition and Physical Activity for Cancer Survivors (Tools To Be Fit)

University of California, San Francisco

NCT05056077

RECRUITING Phase 3 1,000 participants

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Pfizer

NCT07028853

RECRUITING 950 participants

EDRN Prostate MRI Biomarker Study

University of Michigan

NCT03784924

RECRUITING Phase 3 940 participants

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

Novartis Pharmaceuticals

NCT06855277

RECRUITING Phase 2 900 participants

A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study

Astellas Pharma Global Development

NCT02960022

RECRUITING NA 900 participants

Genomics in Michigan to AdJust Outcomes in Prostate canceR (G-MAJOR) for Men With Newly Diagnosed Favorable Risk Prostate Cancer

University of Michigan Rogel Cancer Center

NCT04396808

RECRUITING Phase 3 800 participants

Stereotactic Ablative Radiotherapy (SABR) for the Treatment of Patients With Metastatic Cancer, ID-COMET Trial

Roswell Park Cancer Institute

NCT06563388

RECRUITING NA 800 participants

Cleveland African American Prostate Cancer Project

Case Comprehensive Cancer Center

NCT05469269

RECRUITING 800 participants

Hybrid Intelligence for Trustable Diagnosis and Patient Management of Prostate Cancer (HIT-PIRADS)

Northwestern University

NCT06804785

RECRUITING Phase 3 800 participants

A Study of Changes to Prostate Procedures

Memorial Sloan Kettering Cancer Center

NCT06986083

RECRUITING 750 participants

Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies

National Cancer Institute (NCI)

NCT00451022

RECRUITING Phase 3 710 participants

Androgen Suppression Combined With Nodal Irradiation and Dose Escalated Prostate Treatment

Canadian Cancer Trials Group

NCT06235697

RECRUITING Phase 3 700 participants

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

AstraZeneca

NCT06952803

RECRUITING Phase 4 700 participants

Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

Novartis Pharmaceuticals

NCT05803941

RECRUITING NA 644 participants

Diversity and Inclusion in Research Underpinning Prevention and Therapy Trials

Icahn School of Medicine at Mount Sinai

NCT05146297

RECRUITING Phase 3 608 participants

Adjuvant Curcumin to Assess Recurrence Free Survival in Patients Who Have Had a Radical Prostatectomy

yair lotan

NCT02064673

RECRUITING NA 600 participants

Clinical Trial of Approaches to Prostate Cancer Surgery

Weill Medical College of Cornell University

NCT05155501

RECRUITING 550 participants

Upright MRI for Prostate Cancer Screening

Icahn School of Medicine at Mount Sinai

NCT03474913

RECRUITING NA 510 participants

Evaluation of an Online Prostate Cancer Screening Decision Aid

David Siegel

NCT06610474

RECRUITING NA 508 participants

Multiparametric Magnetic Resonance Imaging of the Prostate to Assess Disease Progression and Genomics in Patients Undergoing Active Surveillance for Prostate Cancer

National Cancer Institute (NCI)

NCT04692675

RECRUITING NA 500 participants

Diffusion Basis Spectrum Imaging of the Prostate

Washington University School of Medicine

NCT04420702

RECRUITING 500 participants

Focal Therapy for Localized Prostate Cancer

University of California, San Diego

NCT06270043

RECRUITING NA 500 participants

Reduction of Gastrointestinal Toxicity in Prostate Cancer by Proton Spot Placement

Covenant Health Cancer Center

NCT06200259

RECRUITING 500 participants

PROMISE Registry: A Prostate Cancer Registry of Outcomes and Germline Mutations for Improved Survival and Treatment Effectiveness

Prostate Cancer Clinical Trials Consortium

NCT04995198

RECRUITING 500 participants

ART-Pro: Clinical Trial Evaluating Biparametric MRI and Advanced, Quantitative Diffusion MRI for Detection of Prostate Cancer

University of California, San Diego

NCT06579417

RECRUITING NA 483 participants

Transrectal Ultrasound Robot-Assisted Prostate Biopsy

Johns Hopkins University

NCT02871726

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Phase Distribution

PhaseTrial count
Phase 1 156
Phase 2 188
Phase 3 62
Phase 4 13

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Prostate Cancer right now

275 recruiting of 749 indexed (37% open).

Phase mix: 75 late (III/IV) vs 344 early (I/II) (early-phase heavy).

Top sponsor: Memorial Sloan Kettering Cancer Center (53 trials), 9 others listed. 50 shown below, recruiting first. #4 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Prostate Cancer?

PlainTrial tracks 749 US clinical trials for Prostate Cancer, of which 275 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Prostate Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.