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NCT02919280 · ClinicalTrials.gov registry record

Dallas 2K: A Natural History Study of Depression

A clinical trial of Depression and Depression, Bipolar, sponsored by University of Texas Southwestern Medical Center.

Recruiting
Registry status
2,500
Enrollment target
1
Study location

NCT02919280 is a study of Depression and Depression, Bipolar that is actively recruiting participants, run by University of Texas Southwestern Medical Center. The registered enrollment target is 2,500 participants, above the 783-participant average among 679 other Depression trials with a reported enrollment target (219% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT02919280, a study of Depression and Depression, Bipolar, is actively recruiting participants, sponsored by University of Texas Southwestern Medical Center.

RECRUITING
Registry status
2,500 participants
Enrollment target
1
Study location

Study Summary

The primary objective of this initiative is to implement a prospective study that will allow us to identify and validate biosignatures of response to treatments for depression and depression outcome (using an integrated array of participant specific data: socio-demographic, lifestyle, clinical and behavioral assessments, fluid-based biomarkers, genomics, neuroimaging, EEG, and cell-based assays) in a longitudinal cohort of subjects with elevated symptoms of a depressive disorder. Symptom remission across various treatment options will be assessed using questionnaires for symptom changes, antidepressant treatment tolerability and overall quality of life. Other outcomes generated from this study will include rate of change in quantitative measures of brain function, of depression relevant brain regions correlated with systems-levels behavior and other functional neuro-circuitry MRI measures. Rate of change of specified biochemical biomarkers will also be assessed. Integration of these measures will provide an unmatched understanding into the mechanisms of depression and hold tremendous promise for better disease treatment and associated outcomes.

Interventions

  • OTHER Observational Study

Study Locations (1)

Texas

  • University of Texas Southwestern Medical Center - Dallas

Trial Details

FieldValue
Enrollment Target 2,500 participants
Start Date 2016-06-14
Est. Completion 2036-09

What the Registry Record Tells You About NCT02919280

The ClinicalTrials.gov registry entry for NCT02919280 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 2,500 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 783-participant average among 679 other Depression trials with a reported enrollment target (219% higher). The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Depression appearing as the primary indexed condition, and to 1 intervention - of which Observational Study is the first listed.

NCT02919280 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT02919280 about?

NCT02919280 is a clinical study titled "Dallas 2K: A Natural History Study of Depression". The primary objective of this initiative is to implement a prospective study that will allow us to identify and validate biosignatures of response to treatments for depression and depression outcome (using an integrated array of participant specific data: socio-demographic, lifestyle, clinical and b...

What is the current status of trial NCT02919280?

This trial is currently recruiting. The enrollment target is 2,500 participants. The study started on 2016-06-14. Estimated completion is 2036-09.

What conditions does trial NCT02919280 study?

This clinical trial studies the following conditions: Depression, Depression, Bipolar.

What interventions are being tested in trial NCT02919280?

The interventions under investigation include: Observational Study (OTHER).

Who is sponsoring clinical trial NCT02919280?

This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02919280 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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