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NCT02919280 · ClinicalTrials.gov registry record
Dallas 2K: A Natural History Study of Depression
A clinical trial of Depression and Depression, Bipolar, sponsored by University of Texas Southwestern Medical Center.
- Recruiting
- Registry status
- 2,500
- Enrollment target
- 1
- Study location
NCT02919280: Recruiting study of Depression and Depression, Bipolar, sponsored by University of Texas Southwestern Medical Center.
NCT02919280 is a study of Depression and Depression, Bipolar that is actively recruiting participants, run by University of Texas Southwestern Medical Center. The registered enrollment target is 2,500 participants, above the 783-participant average among 679 other Depression trials with a reported enrollment target (219% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02919280, a study of Depression and Depression, Bipolar, is actively recruiting participants, sponsored by University of Texas Southwestern Medical Center.
- RECRUITING
- Registry status
- 2,500 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary objective of this initiative is to implement a prospective study that will allow us to identify and validate biosignatures of response to treatments for depression and depression outcome (using an integrated array of participant specific data: socio-demographic, lifestyle, clinical and behavioral assessments, fluid-based biomarkers, genomics, neuroimaging, EEG, and cell-based assays) in a longitudinal cohort of subjects with elevated symptoms of a depressive disorder. Symptom remission across various treatment options will be assessed using questionnaires for symptom changes, antidepressant treatment tolerability and overall quality of life. Other outcomes generated from this study will include rate of change in quantitative measures of brain function, of depression relevant brain regions correlated with systems-levels behavior and other functional neuro-circuitry MRI measures. Rate of change of specified biochemical biomarkers will also be assessed. Integration of these measures will provide an unmatched understanding into the mechanisms of depression and hold tremendous promise for better disease treatment and associated outcomes.
Primary Outcome
Assessment of changes in depressive symptom severity over time using PHQ- total scores in participants with non-psychotic depressive disorders.
Conditions Studied
Interventions
- OTHER Observational Study
Study Locations (1)
Texas
- University of Texas Southwestern Medical Center - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,500 participants |
| Start Date | 2016-06-14 |
| Est. Completion | 2036-09 |
What NCT02919280 shows while recruiting
NCT02919280 is an observational study that tracks outcomes without assigning an intervention. Its 2,500 participants enrollment target places it among the larger protocols in the corpus, above the 783-participant average among 679 other Depression trials with a reported enrollment target (219% higher).
The record links to 2 conditions, with Depression appearing as the primary indexed condition, and to 1 intervention - of which Observational Study is the first listed.
NCT02919280 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT02919280 about?
NCT02919280 is a clinical study titled "Dallas 2K: A Natural History Study of Depression". The primary objective of this initiative is to implement a prospective study that will allow us to identify and validate biosignatures of response to treatments for depression and depression outcome (using an integrated array of participant specific data: socio-demographic, lifestyle, clinical and b...
What is the current status of trial NCT02919280?
This trial is currently recruiting. The enrollment target is 2,500 participants. The study started on 2016-06-14. Estimated completion is 2036-09.
What conditions does trial NCT02919280 study?
This clinical trial studies the following conditions: Depression, Depression, Bipolar.
What interventions are being tested in trial NCT02919280?
The interventions under investigation include: Observational Study (OTHER).
Who is sponsoring clinical trial NCT02919280?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02919280 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02919280's enrollment target sits among peer trials
2,500 22nd of 679 higher than 657 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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