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NCT04838678 · ClinicalTrials.gov registry record · Early Phase 1
Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)
A Early Phase 1 study of Obesity and Hypertension, sponsored by University of Texas Southwestern Medical Center.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT04838678: Recruiting Early Phase 1 study of Obesity and Hypertension, sponsored by University of Texas Southwestern Medical Center.
NCT04838678 is a Early Phase 1 study of Obesity and Hypertension that is actively recruiting participants, run by University of Texas Southwestern Medical Center. The registered enrollment target is 100 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04838678, a Early Phase 1 study of Obesity and Hypertension, is actively recruiting participants, sponsored by University of Texas Southwestern Medical Center.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to understand how the nervous system communicates to blood vessels to increase blood pressure during stress. The study will also investigate how hypertension and obesity influence the nervous system and vascular function. The study will involve measuring sympathetic nervous system activity and blood flow during common laboratory physiological stress protocols (e.g. hypoxia, exercise), and in response to infusion of drugs that cause vasodilation or vasoconstriction.
Primary Outcome
brachial and femoral artery blood flow
Conditions Studied
Interventions
- DRUG Neuropeptide Y
Study Locations (1)
Texas
- University of Texas Southwestern Medical Center - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2021-07-18 |
| Est. Completion | 2026-08-31 |
| Phase | Early Phase 1 |
What NCT04838678 shows while recruiting
NCT04838678 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (88% lower).
The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 1 intervention - of which Neuropeptide Y is the first listed.
NCT04838678 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT04838678 about?
NCT04838678 is a clinical study titled "Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)". The purpose of this study is to understand how the nervous system communicates to blood vessels to increase blood pressure during stress. The study will also investigate how hypertension and obesity influence the nervous system and vascular function. The study will involve measuring sympathetic nerv...
What is the current status of trial NCT04838678?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 100 participants. The study started on 2021-07-18. Estimated completion is 2026-08-31.
What conditions does trial NCT04838678 study?
This clinical trial studies the following conditions: Obesity, Hypertension.
What interventions are being tested in trial NCT04838678?
The interventions under investigation include: Neuropeptide Y (DRUG).
Who is sponsoring clinical trial NCT04838678?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04838678 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04838678's enrollment target sits among peer trials
100 478th of 1053 higher than 555 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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