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NCT05665244 · ClinicalTrials.gov registry record

Laryngeal Cryotherapy for Refractory Neurogenic Cough

A clinical trial of Upper-Airway Cough Syndrome, sponsored by University of Texas Southwestern Medical Center.

Recruiting
Registry status
28
Enrollment target
1
Study location

NCT05665244: Recruiting study of Upper-Airway Cough Syndrome, sponsored by University of Texas Southwestern Medical Center.

NCT05665244 is a study of Upper-Airway Cough Syndrome that is actively recruiting participants, run by University of Texas Southwestern Medical Center. The registered enrollment target is 28 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05665244, a study of Upper-Airway Cough Syndrome, is actively recruiting participants, sponsored by University of Texas Southwestern Medical Center.

RECRUITING
Registry status
28 participants
Enrollment target
1
Study location

Study Summary

This study aims to evaluate the safety and efficacy of upper aerodigestive tract cryotherapy treatment in patients with refractory neurogenic cough in a prospective pilot study with a validated patient reported outcome measure

Primary Outcome

This is a validated patient reported outcome measure for chronic cough. This is a questionnaire of 10 questions about cough symptoms, each question is rated on a scale of 0-4 by the patient. The higher the CSI total score the worsen the cough symptoms are for the patient. The CSI will be compared across 5 time points (Pre-Laryngeal Cryotherapy, 1 week post cryotherapy, 1 month post cryotherapy, 3 months post cryotherapy and 6 months post cryotherapy) using repeated measures one-way ANOVA. Post-h

Interventions

  • PROCEDURE Laryngeal cryotherapy
  • DEVICE Cryoprobe

Study Locations (1)

Texas

  • UT Southwestern Medical Center - Dallas

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2022-12-26
Est. Completion 2027-02

What NCT05665244 shows while recruiting

NCT05665244 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 28 participants, a relatively small participant target.

The record links to 1 condition, with Upper-Airway Cough Syndrome appearing as the primary indexed condition, and to 2 interventions - of which Laryngeal cryotherapy is the first listed.

NCT05665244 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT05665244 about?

NCT05665244 is a clinical study titled "Laryngeal Cryotherapy for Refractory Neurogenic Cough". This study aims to evaluate the safety and efficacy of upper aerodigestive tract cryotherapy treatment in patients with refractory neurogenic cough in a prospective pilot study with a validated patient reported outcome measure

What is the current status of trial NCT05665244?

This trial is currently recruiting. The enrollment target is 28 participants. The study started on 2022-12-26. Estimated completion is 2027-02.

What conditions does trial NCT05665244 study?

This clinical trial studies the following conditions: Upper-Airway Cough Syndrome.

What interventions are being tested in trial NCT05665244?

The interventions under investigation include: Laryngeal cryotherapy (PROCEDURE), Cryoprobe (DEVICE).

Who is sponsoring clinical trial NCT05665244?

This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05665244 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Source: ClinicalTrials.gov NCT05665244, the US trial registry maintained by the National Library of Medicine. NCT05665244 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.