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ClinicalTrials.gov 6 recruiting now official registry

Hyperthermia clinical trials

Every US clinical trial registered for Hyperthermia — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

16 US clinical trials · 6 currently recruiting

The research picture

Hyperthermia has 16 registered US clinical trials, 6 of them open to new participants right now — about 38% of the total.

6
recruiting participants now
38%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
6
top sponsor: University of Texas Southwestern Medical Center

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING NA 100 participants

Heat Waves and the Elderly - Cooling Modalities

University of Texas Southwestern Medical Center

NCT05484739

RECRUITING NA 88 participants

IEEM-Heat and Heart Failure

University of Texas Southwestern Medical Center

NCT06961929

RECRUITING 70 participants

IEEM- Work:Rest Cycles in Burn Survivors- Humidity

University of Texas Southwestern Medical Center

NCT06966336

RECRUITING NA 50 participants

The Effectiveness of Emergency Room Protocols for Treating Hyperthermia

University of Colorado, Colorado Springs

NCT07433036

RECRUITING NA 24 participants

Predicting Responses to Exhausting, Prolonged, And Repeated Exercise Demands (PREPARED) for Heat

State University of New York at Buffalo

NCT06475339

RECRUITING 24 participants

Impact of Extreme Heat on Myocardial Blood Flow and Flow Reserve in Young and Older Adults

University of Texas Southwestern Medical Center

NCT06842784

ACTIVE NOT RECRUITING NA 9 participants

Skin Surface and Intradermal Temperature Responses to Heat Stress

University of Texas Southwestern Medical Center

NCT06593067

COMPLETED NA 245 participants

Genomic Medicine Risk Assessment Care for Everyone - Implementation Phase

Duke University

NCT06278883

COMPLETED NA 28 participants

Effect of Heat Stress on Global LV Function in Anesthetized Humans

University of California, San Diego

NCT04553900

COMPLETED NA 24 participants

Comparison of Bi-environmental Conditions During Occupational Related Activity

University of Connecticut

NCT05059730

COMPLETED NA 22 participants

Aging and Gastrointestinal Barrier Function

University of Texas Southwestern Medical Center

NCT05816551

COMPLETED NA 18 participants

Renal Considerations in the Heat Stress Recommendations (Aim2)

Indiana University

NCT05458843

COMPLETED NA 12 participants

Military Alerting System for Monitoring Body Temperature During Active Cooling

University of Connecticut

NCT04431596

COMPLETED NA 12 participants

Physiological and Thermoregulatory Responses of Body Cooling During Cycling in a Hot Environment

University of Connecticut

NCT04715711

COMPLETED NA 12 participants

Impact of Neck Cooling Collar on Exercise Performance in the Heat

University of Connecticut

NCT05135117

COMPLETED NA 12 participants

Impact of ICE on Exercise Performance in the Heat

University of Connecticut

NCT04596618

Phase Distribution

Phase data not available

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Hyperthermia Trial Landscape

ClinicalTrials.gov lists 16 US studies indexed under Hyperthermia, and 6 of those are currently open to recruitment — roughly 38% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Hyperthermia shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 0 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Hyperthermia is led by University of Texas Southwestern Medical Center with 6 indexed trials, alongside 6 other organizations in the top contributor list. The list on this page surfaces up to 16 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Hyperthermia?

PlainTrial tracks 16 US clinical trials for Hyperthermia, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Hyperthermia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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