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NCT01875588 · ClinicalTrials.gov registry record
Thinking and Memory Problems in People With HIV
A clinical trial of HIV Positive, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Recruiting
- Registry status
- 1,150
- Enrollment target
- 1
- Study location
NCT01875588 is a study of HIV Positive that is actively recruiting participants, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 1,150 participants, above the 292-participant average among 3 other HIV Positive trials with a reported enrollment target (294% higher). The trial reports 1 study location across 1 state.
The verdict
NCT01875588, a study of HIV Positive, is actively recruiting participants, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- RECRUITING
- Registry status
- 1,150 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: \- People with human immunodeficiency virus (HIV) can sometimes develop thinking and memory problems. These problems can vary widely, from few symptoms to severe problems with memory and concentration. It initially was thought that good HIV treatment could prevent almost all HIV-related memory problems. However, even people with low HIV viral loads can have these problems. It may be caused by HIV affecting the brain and spinal fluid. It is not yet clear why HIV causes these problems and why they may be worse in some people than others. Researchers want to study people with HIV and healthy volunteers to see how HIV may affect people with only small amounts of the virus in their blood. Objectives: \- To study thinking and memory problems in individuals with HIV that is otherwise controlled with medications. Eligibility: * Individuals between 18 of age or older whose HIV has been controlled with medications for at least 1 year. * Healthy volunteers between 18 of age or older. Design: * Participants will be screened with a physical exam and medical history. Blood and urine samples will be collected. A neurological test will also be given. Participants will have a baseline imaging study of the brain. * Within 12 weeks of the first visit, participants will have a second visit. Additional blood samples will be drawn. Another brain imaging study will be performed. * Within 8 weeks of the second visit, participants will have a third visit to collect more blood samples. They will also provide spinal fluid samples, either as a single visit or a longer procedure. * After this visit, participants will return every 12 months for up to 10 years. Blood samples will be collected as needed at these visits. Thinking and memory tests and imaging studies may also be given as needed. Spinal fluid may be collected at one visit a year.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,150 participants |
| Start Date | 2013-07-08 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01875588
The ClinicalTrials.gov registry entry for NCT01875588 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 1,150 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 292-participant average among 3 other HIV Positive trials with a reported enrollment target (294% higher). The listed sponsor is National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with HIV Positive appearing as the primary indexed condition, and to 0 interventions.
NCT01875588 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT01875588 about?
NCT01875588 is a clinical study titled "Thinking and Memory Problems in People With HIV". Background: \- People with human immunodeficiency virus (HIV) can sometimes develop thinking and memory problems. These problems can vary widely, from few symptoms to severe problems with memory and concentration. It initially was thought that good HIV treatment could prevent almost all HIV-related...
What is the current status of trial NCT01875588?
This trial is currently recruiting. The enrollment target is 1,150 participants. The study started on 2013-07-08.
What conditions does trial NCT01875588 study?
This clinical trial studies the following conditions: HIV Positive.
Who is sponsoring clinical trial NCT01875588?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01875588 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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